Barkley Women's Reproductive Health Practice
ACTUAL EXAM ALL QUESTIONS AND ANSWERS
ALREADY GRADED A+. 100% VERIFIED
SOLUTIONS | UPDATED PER LATEST
GUIDELINES | GRADED A+
Section 1: Well-Woman Care & Preventive Screening
Question 1
A 24-year-old female requests routine cervical cancer screening. According to ASCCP guidelines,
what is the standard protocol for her age group?
A. Cytology alone every 3 years
B. Primary HPV testing every 5 years
C. Cytology with HPV co-testing every 3 years
D. Co-testing every 5 years
Correct Answer: A
Rationale: ASCCP guidelines mandate cytology alone for ages 21-29. Primary HPV testing and
co-testing are avoided in this age group due to high transient viral clearance rates, which could
lead to unnecessary procedures and patient anxiety .
Question 2
A 35-year-old female presents for a routine checkup. What is the preferred cervical cancer
screening strategy for her age group?
A. Cytology alone every 3 years
B. Primary HPV testing every 5 years
C. Cytology with HPV co-testing every 10 years
D. Cytology every 5 years
Correct Answer: B
,Rationale: For ages 30-65, screening with primary HPV testing every 5 years or co-testing
(cytology + HPV) every 5 years provides optimal reassurance and sensitivity. Primary HPV testing
is preferred due to its high sensitivity for detecting high-grade cervical lesions .
Question 3
A 22-year-old female's Pap result shows ASC-US (Atypical Squamous Cells of Undetermined
Significance). What is the next step?
A. Immediate colposcopy
B. Repeat cytology in 12 months
C. Perform reflex HPV testing
D. Perform LEEP procedure
Correct Answer: B
Rationale: In patients aged 21-24, low-grade lesions frequently regress spontaneously. Repeat
cytology in 12 months minimizes unnecessary cervical procedures. Reflex HPV testing is not
recommended for this age group due to the high prevalence of transient HPV infection .
Question 4
A 27-year-old female presents with LSIL and a positive HPV test. What is the appropriate next
step?
A. Repeat Pap in 12 months
B. Immediate colposcopy
C. Perform LEEP procedure
D. Repeat Pap in 6 months
Correct Answer: B
Rationale: For women age 25 and older with LSIL and positive HPV, immediate colposcopy is
required to check for underlying high-grade dysplasia. The combination of LSIL and positive HPV
indicates a higher risk of CIN 2+ lesions that requires evaluation .
Question 5
A 40-year-old woman has a Pap smear showing HSIL. What is the next best step?
A. Repeat Pap smear in one year
B. Colposcopy with directed biopsy
, C. Loop electrosurgical excision procedure (LEEP)
D. Hysterectomy
Correct Answer: B
Rationale: HSIL on cervical cytology requires colposcopy with directed biopsy to obtain
histologic confirmation and rule out invasive cancer. Treatment decisions should be based on
biopsy results, not cytology alone .
Question 6
A 30-year-old woman has a Pap test with HPV co-testing showing NILM and HPV negative. What
is the recommended follow-up?
A. Repeat co-testing in 1 year
B. Repeat co-testing in 3 years
C. Repeat co-testing in 5 years
D. Colposcopy
Correct Answer: C
Rationale: For women aged 30-65 with a negative co-test (NILM and HPV negative), routine
screening is recommended no sooner than every 5 years. This extended interval reflects the low
risk of developing high-grade disease in this group .
Question 7
Which of the following is a known risk factor for cervical cancer?
A. Multiparity
B. Persistent infection with high-risk HPV types 16 and 18
C. Early menopause
D. Endometriosis
Correct Answer: B
Rationale: Persistent infection with oncogenic (high-risk) HPV types, especially 16 and 18, is the
primary cause of cervical cancer. The vast majority of cervical cancers are associated with
persistent HPV infection, making it the most significant risk factor .
Question 8
The quadrivalent HPV vaccine (Gardasil) protects against which HPV types?
ACTUAL EXAM ALL QUESTIONS AND ANSWERS
ALREADY GRADED A+. 100% VERIFIED
SOLUTIONS | UPDATED PER LATEST
GUIDELINES | GRADED A+
Section 1: Well-Woman Care & Preventive Screening
Question 1
A 24-year-old female requests routine cervical cancer screening. According to ASCCP guidelines,
what is the standard protocol for her age group?
A. Cytology alone every 3 years
B. Primary HPV testing every 5 years
C. Cytology with HPV co-testing every 3 years
D. Co-testing every 5 years
Correct Answer: A
Rationale: ASCCP guidelines mandate cytology alone for ages 21-29. Primary HPV testing and
co-testing are avoided in this age group due to high transient viral clearance rates, which could
lead to unnecessary procedures and patient anxiety .
Question 2
A 35-year-old female presents for a routine checkup. What is the preferred cervical cancer
screening strategy for her age group?
A. Cytology alone every 3 years
B. Primary HPV testing every 5 years
C. Cytology with HPV co-testing every 10 years
D. Cytology every 5 years
Correct Answer: B
,Rationale: For ages 30-65, screening with primary HPV testing every 5 years or co-testing
(cytology + HPV) every 5 years provides optimal reassurance and sensitivity. Primary HPV testing
is preferred due to its high sensitivity for detecting high-grade cervical lesions .
Question 3
A 22-year-old female's Pap result shows ASC-US (Atypical Squamous Cells of Undetermined
Significance). What is the next step?
A. Immediate colposcopy
B. Repeat cytology in 12 months
C. Perform reflex HPV testing
D. Perform LEEP procedure
Correct Answer: B
Rationale: In patients aged 21-24, low-grade lesions frequently regress spontaneously. Repeat
cytology in 12 months minimizes unnecessary cervical procedures. Reflex HPV testing is not
recommended for this age group due to the high prevalence of transient HPV infection .
Question 4
A 27-year-old female presents with LSIL and a positive HPV test. What is the appropriate next
step?
A. Repeat Pap in 12 months
B. Immediate colposcopy
C. Perform LEEP procedure
D. Repeat Pap in 6 months
Correct Answer: B
Rationale: For women age 25 and older with LSIL and positive HPV, immediate colposcopy is
required to check for underlying high-grade dysplasia. The combination of LSIL and positive HPV
indicates a higher risk of CIN 2+ lesions that requires evaluation .
Question 5
A 40-year-old woman has a Pap smear showing HSIL. What is the next best step?
A. Repeat Pap smear in one year
B. Colposcopy with directed biopsy
, C. Loop electrosurgical excision procedure (LEEP)
D. Hysterectomy
Correct Answer: B
Rationale: HSIL on cervical cytology requires colposcopy with directed biopsy to obtain
histologic confirmation and rule out invasive cancer. Treatment decisions should be based on
biopsy results, not cytology alone .
Question 6
A 30-year-old woman has a Pap test with HPV co-testing showing NILM and HPV negative. What
is the recommended follow-up?
A. Repeat co-testing in 1 year
B. Repeat co-testing in 3 years
C. Repeat co-testing in 5 years
D. Colposcopy
Correct Answer: C
Rationale: For women aged 30-65 with a negative co-test (NILM and HPV negative), routine
screening is recommended no sooner than every 5 years. This extended interval reflects the low
risk of developing high-grade disease in this group .
Question 7
Which of the following is a known risk factor for cervical cancer?
A. Multiparity
B. Persistent infection with high-risk HPV types 16 and 18
C. Early menopause
D. Endometriosis
Correct Answer: B
Rationale: Persistent infection with oncogenic (high-risk) HPV types, especially 16 and 18, is the
primary cause of cervical cancer. The vast majority of cervical cancers are associated with
persistent HPV infection, making it the most significant risk factor .
Question 8
The quadrivalent HPV vaccine (Gardasil) protects against which HPV types?
