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NR 293 ACID-CONTROLLING DRUGS CHAPTER 50 | COMPREHENSIVE PHARMACOLOGY STUDY GUIDE, PRACTICE QUESTIONS & ANSWERS 2026/2027

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NR 293 ACID-CONTROLLING DRUGS CHAPTER 50 | COMPREHENSIVE PHARMACOLOGY STUDY GUIDE, PRACTICE QUESTIONS & ANSWERS 2026/2027

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NR 293 ACID-CONTROLLING DRUGS CHAPTER 50 | COMPREHENSIVE
PHARMACOLOGY STUDY GUIDE, PRACTICE QUESTIONS & ANSWERS 2026/2027

What are the functions of antacids? - correct answer ✔✔Neutralize acid secretions (decrease acidity,
decrease pain)

*Do not prevent* overproduction of acid.

Promote gastric mucosal defensive mechanisms.

Stimulate secretion of mucus, bicarbonate and prostaglandins.

What are the indications for antacids? - correct answer ✔✔Acute relief of symptoms (ie pain) associated
with acid-related disorders (peptic ulcers, gastritis, gastric hyperacidity and heart burn)

What are the contraindications of antacids? - correct answer ✔✔Allergy

Severe RF

Electrolyte disturbance

GI obstruction

Pregnancy (usually safe, consult HCP first)

What are the adverse effects of antacids? - correct answer ✔✔Product specific

May mask symptoms of serious underlying disease.

What are the interactions with antacids? - correct answer ✔✔Chelation (binds and inactivates other
drug)

Adsorption (decreased absorption of other drug)

*Do not give antacids within 1-2 hours of other medications.*

What are the functions of histamine 2 receptor antagonists? - correct answer ✔✔"tidine"

Antihistamine: Suppresses acid secretion by blocking the H2 receptors on acid-producing parietal cells.

What are the indications for histamine 2 receptor antagonists? - correct answer ✔✔Treatment of GERD,
PUD, erosive esophagitis, adjunct therapy to control upper GI bleeding, Zollinger-Ellison syndrome.

Prophylaxis of stress ulcers

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