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1. A healthcare provider (HCP) has a patient beginning pramipexole for
Parkinson's disease. Which lab test requires monitoring?
A. Liver function
B. CPK (creatine phosphokinase)
C. Blood glucose
D. Platelet count
Rationale: Pramipexole has been associated with rhabdomyolysis in rare cases, so
CPK levels are monitored to detect muscle breakdown.
2. A patient is taking selegiline (Eldepryl) for Parkinson's disease. A drug
interaction between selegiline and meperidine can result in:
A. Severe hypotension
B. Muscle rigidity
C. Hyperglycemia
D. Bradycardia
Rationale: Selegiline is an MAO-B inhibitor; combined with meperidine, it can
trigger a dangerous serotonergic/excitatory reaction, including muscle rigidity,
hyperthermia, and altered consciousness.
3. When teaching a patient about baclofen (Lioresal), the nurse should include
which instruction?
, A. Take the medication with food only
B. Avoid driving until the drug's effects are evident
C. Increase fluid intake significantly
D. Discontinue the drug abruptly if drowsy
Rationale: Baclofen commonly causes sedation and dizziness, especially when
starting therapy, making driving unsafe until effects are known.
4. The HCP monitors for which effect in a patient taking donepezil for
Alzheimer's disease?
A. Constipation
B. Nausea
C. Hypertension
D. Weight gain
Rationale: Donepezil is a cholinesterase inhibitor; GI effects like nausea (and
vomiting/diarrhea) are common due to increased cholinergic activity.
5. Which of the following is recommended for patients beginning to take
carbamazepine?
A. Start at the highest effective dose immediately
B. Begin taking the drug at a low dosage
C. Take the drug only as needed for symptoms
D. Avoid all lab monitoring once therapy starts
Rationale: Carbamazepine is typically titrated upward gradually from a low
starting dose to minimize adverse effects and assess tolerance.
6. A patient is taking dantrolene for muscle spasms. Which lab test should be
monitored?