1000 Flashcards Pharmacy Technician Certification Board (PTCB)
What is the generic name for Lipitor®, and what drug Lipitor® is the brand name for atorvastatin, which belongs to the HMG-CoA
class does it belong to? reductase inhibitor class (statins). It is used primarily to lower LDL cholesterol
and reduce cardiovascular risk.
A prescription is written for "metoprolol succinate ER." ER means extended-release. It should not be substituted with immediate-
What is the importance of the "ER" designation? release metoprolol tartrate because the dosage form, release characteristics,
and dosing schedule differ significantly.
The generic name for Coumadin® is ________. Warfarin. It is an anticoagulant with many serious drug and food interactions.
A patient taking warfarin starts taking TMP-SMX may increase warfarin levels and INR, greatly increasing bleeding
trimethoprim/sulfamethoxazole. Why is this interaction risk. This is considered a major drug-drug interaction.
dangerous?
What classification does albuterol belong to, and what Albuterol is a short-acting beta2 agonist (SABA) used for rapid
is its primary use? bronchodilation in asthma or COPD.
Page 1 of 123
,1000 Flashcards Pharmacy Technician Certification Board (PTCB)
Omeprazole and pantoprazole are therapeutically False. Both are proton pump inhibitors, but exact therapeutic equivalence
equivalent in all situations. Explain. depends on dose conversion, patient response, insurance formularies, and
prescriber intent.
What is the generic name of Synthroid®, and what Levothyroxine. Patients should take it on an empty stomach and avoid
counseling point is critical? switching manufacturers without provider knowledge because bioavailability
may vary.
A patient taking sildenafil is prescribed nitroglycerin. This combination is contraindicated because it may cause severe hypotension
What should the technician recognize? due to additive vasodilatory effects.
What class of medication is lisinopril, and what major Lisinopril is an ACE inhibitor. Major adverse effects include cough,
adverse effect should be monitored? hyperkalemia, angioedema, and hypotension.
Januvia® is the brand name for ________. Sitagliptin. It is a DPP-4 inhibitor used for type 2 diabetes.
A patient allergic to sulfa drugs asks whether Hydrochlorothiazide contains a sulfonamide component and may pose a
hydrochlorothiazide is safe. What should be cross-sensitivity risk in some patients. The pharmacist should evaluate severity
considered? of allergy history.
What is the difference between therapeutic Pharmaceutical equivalents contain the same active ingredient, dosage form,
equivalence and pharmaceutical equivalence? strength, and route. Therapeutic equivalents are expected to produce the
same clinical effect and safety profile.
Page 2 of 123
,1000 Flashcards Pharmacy Technician Certification Board (PTCB)
What does the Orange Book primarily identify? FDA-approved drug products and therapeutic equivalence evaluations
between brand and generic medications.
Why is grapefruit juice contraindicated with certain Grapefruit inhibits CYP3A4 metabolism, increasing statin concentration and
statins like simvastatin? risk of rhabdomyolysis and liver toxicity.
What drug class does sertraline belong to? Sertraline is an SSRI antidepressant used for depression, anxiety, PTSD, and
OCD.
A patient taking MAOIs eats aged cheese and Tyramine interaction. MAOIs prevent tyramine breakdown, causing dangerous
develops severe hypertension. What caused this? hypertensive crises.
The brand name for apixaban is ________. Eliquis®. It is an oral anticoagulant factor Xa inhibitor.
What major interaction exists between opioids and Combined CNS depression may cause respiratory depression, sedation, coma,
benzodiazepines? or death.
What class is metformin, and what serious adverse Metformin is a biguanide antidiabetic. Rare but serious adverse effect: lactic
effect is associated with it? acidosis.
Page 3 of 123
, 1000 Flashcards Pharmacy Technician Certification Board (PTCB)
Why should isotretinoin never be used during It is highly teratogenic and may cause severe birth defects. Patients must
pregnancy? follow strict REMS/iPLEDGE requirements.
What is the generic name of Keppra®, and what is its Levetiracetam. It is an anticonvulsant used for seizure disorders.
use?
A patient takes digoxin and develops nausea and Possible digoxin toxicity, which may be life-threatening and requires
yellow vision. What may this indicate? immediate evaluation.
What is the primary purpose of therapeutic Replacing a prescribed drug with a chemically different but therapeutically
substitution? similar drug, usually under formulary guidelines or pharmacist authority.
All AB-rated generics are therapeutically equivalent to True. AB-rated drugs in the FDA Orange Book are considered therapeutically
their reference brand products. Explain. equivalent and bioequivalent.
What drug class does prednisone belong to? Corticosteroids. They reduce inflammation and suppress immune responses.
Page 4 of 123
What is the generic name for Lipitor®, and what drug Lipitor® is the brand name for atorvastatin, which belongs to the HMG-CoA
class does it belong to? reductase inhibitor class (statins). It is used primarily to lower LDL cholesterol
and reduce cardiovascular risk.
A prescription is written for "metoprolol succinate ER." ER means extended-release. It should not be substituted with immediate-
What is the importance of the "ER" designation? release metoprolol tartrate because the dosage form, release characteristics,
and dosing schedule differ significantly.
The generic name for Coumadin® is ________. Warfarin. It is an anticoagulant with many serious drug and food interactions.
A patient taking warfarin starts taking TMP-SMX may increase warfarin levels and INR, greatly increasing bleeding
trimethoprim/sulfamethoxazole. Why is this interaction risk. This is considered a major drug-drug interaction.
dangerous?
What classification does albuterol belong to, and what Albuterol is a short-acting beta2 agonist (SABA) used for rapid
is its primary use? bronchodilation in asthma or COPD.
Page 1 of 123
,1000 Flashcards Pharmacy Technician Certification Board (PTCB)
Omeprazole and pantoprazole are therapeutically False. Both are proton pump inhibitors, but exact therapeutic equivalence
equivalent in all situations. Explain. depends on dose conversion, patient response, insurance formularies, and
prescriber intent.
What is the generic name of Synthroid®, and what Levothyroxine. Patients should take it on an empty stomach and avoid
counseling point is critical? switching manufacturers without provider knowledge because bioavailability
may vary.
A patient taking sildenafil is prescribed nitroglycerin. This combination is contraindicated because it may cause severe hypotension
What should the technician recognize? due to additive vasodilatory effects.
What class of medication is lisinopril, and what major Lisinopril is an ACE inhibitor. Major adverse effects include cough,
adverse effect should be monitored? hyperkalemia, angioedema, and hypotension.
Januvia® is the brand name for ________. Sitagliptin. It is a DPP-4 inhibitor used for type 2 diabetes.
A patient allergic to sulfa drugs asks whether Hydrochlorothiazide contains a sulfonamide component and may pose a
hydrochlorothiazide is safe. What should be cross-sensitivity risk in some patients. The pharmacist should evaluate severity
considered? of allergy history.
What is the difference between therapeutic Pharmaceutical equivalents contain the same active ingredient, dosage form,
equivalence and pharmaceutical equivalence? strength, and route. Therapeutic equivalents are expected to produce the
same clinical effect and safety profile.
Page 2 of 123
,1000 Flashcards Pharmacy Technician Certification Board (PTCB)
What does the Orange Book primarily identify? FDA-approved drug products and therapeutic equivalence evaluations
between brand and generic medications.
Why is grapefruit juice contraindicated with certain Grapefruit inhibits CYP3A4 metabolism, increasing statin concentration and
statins like simvastatin? risk of rhabdomyolysis and liver toxicity.
What drug class does sertraline belong to? Sertraline is an SSRI antidepressant used for depression, anxiety, PTSD, and
OCD.
A patient taking MAOIs eats aged cheese and Tyramine interaction. MAOIs prevent tyramine breakdown, causing dangerous
develops severe hypertension. What caused this? hypertensive crises.
The brand name for apixaban is ________. Eliquis®. It is an oral anticoagulant factor Xa inhibitor.
What major interaction exists between opioids and Combined CNS depression may cause respiratory depression, sedation, coma,
benzodiazepines? or death.
What class is metformin, and what serious adverse Metformin is a biguanide antidiabetic. Rare but serious adverse effect: lactic
effect is associated with it? acidosis.
Page 3 of 123
, 1000 Flashcards Pharmacy Technician Certification Board (PTCB)
Why should isotretinoin never be used during It is highly teratogenic and may cause severe birth defects. Patients must
pregnancy? follow strict REMS/iPLEDGE requirements.
What is the generic name of Keppra®, and what is its Levetiracetam. It is an anticonvulsant used for seizure disorders.
use?
A patient takes digoxin and develops nausea and Possible digoxin toxicity, which may be life-threatening and requires
yellow vision. What may this indicate? immediate evaluation.
What is the primary purpose of therapeutic Replacing a prescribed drug with a chemically different but therapeutically
substitution? similar drug, usually under formulary guidelines or pharmacist authority.
All AB-rated generics are therapeutically equivalent to True. AB-rated drugs in the FDA Orange Book are considered therapeutically
their reference brand products. Explain. equivalent and bioequivalent.
What drug class does prednisone belong to? Corticosteroids. They reduce inflammation and suppress immune responses.
Page 4 of 123
