ONS ONCC
Chemotherapy Immunotherapy Certificate Renewal 2026/2027
| Practice Questions, Answers & Detailed Rationales
Resource Features
➢ ONS/ONCC renewal-focused practice questions
➢ Answers for self-assessment
➢ Detailed rationales
➢ Oncology clinical scenarios
➢ Chemotherapy review
➢ Immunotherapy review
, ONS ONCC Chemotherapy Immunotherapy
Certificate Renewal 2026/2027 | Practice
Questions, Answers & Detailed Rationales
Item 1
Question: What is the main benefit of neoadjuvant chemotherapy
in breast cancer patients?
A) It significantly increases overall survival compared to adjuvant
therapy.
B) It eliminates the need for any surgical intervention.
C) It can shrink the tumor enough to allow lumpectomy instead of
mastectomy.
D) It reduces the total number of chemotherapy cycles needed.
Correct Answer: C
Rationale: The document clearly states that neoadjuvant therapy
does not increase survival compared to adjuvant therapy. Its
primary benefit is changing surgical options; if the tumor shrinks
enough, the patient may only require a lumpectomy plus
radiation instead of a mastectomy.
,Item 2
Question: A comprehensive geriatric assessment (CGA) covers all
of the following EXCEPT:
A) Functional status and comorbidities.
B) Cognitive function and nutritional status.
C) Genetic mutation testing and tumor markers.
D) Polypharmacy and medication review.
Correct Answer: C
Rationale: According to the NCCN Older Adult Oncology
Guidelines, a CGA includes functional status, socioeconomic
issues, psychosocial distress, comorbidities, cognitive function,
nutritional status, polypharmacy, and medication review. Genetic
mutation testing and tumor markers are not components of a
CGA.
Item 3
Question: According to the NCCN Older Adult Oncology
Guidelines (version 1.2015), more than 60% of cancers in the
United States occur in people age _____ and older.
, A) 55
B) 60
C) 65
D) 70
Correct Answer: C
Rationale: The document explicitly states the threshold is age 65.
This age cutoff is used to define the older adult population for
cancer care guidelines, reflecting the demographic shift where
nearly half (46%) of cancer survivors are 70 or older.
Item 4
Question: A patient is receiving docetaxel and carboplatin
through a port. What is the best explanation for why a port was
placed rather than using a peripheral IV?
A) Both agents are classified as vesicants requiring central access.
B) The patient's age makes peripheral IVs unsafe.
C) Docetaxel is an irritant that can cause significant extravasation
reactions.
D) Carboplatin must be infused through a port to be effective.
Correct Answer: C
Chemotherapy Immunotherapy Certificate Renewal 2026/2027
| Practice Questions, Answers & Detailed Rationales
Resource Features
➢ ONS/ONCC renewal-focused practice questions
➢ Answers for self-assessment
➢ Detailed rationales
➢ Oncology clinical scenarios
➢ Chemotherapy review
➢ Immunotherapy review
, ONS ONCC Chemotherapy Immunotherapy
Certificate Renewal 2026/2027 | Practice
Questions, Answers & Detailed Rationales
Item 1
Question: What is the main benefit of neoadjuvant chemotherapy
in breast cancer patients?
A) It significantly increases overall survival compared to adjuvant
therapy.
B) It eliminates the need for any surgical intervention.
C) It can shrink the tumor enough to allow lumpectomy instead of
mastectomy.
D) It reduces the total number of chemotherapy cycles needed.
Correct Answer: C
Rationale: The document clearly states that neoadjuvant therapy
does not increase survival compared to adjuvant therapy. Its
primary benefit is changing surgical options; if the tumor shrinks
enough, the patient may only require a lumpectomy plus
radiation instead of a mastectomy.
,Item 2
Question: A comprehensive geriatric assessment (CGA) covers all
of the following EXCEPT:
A) Functional status and comorbidities.
B) Cognitive function and nutritional status.
C) Genetic mutation testing and tumor markers.
D) Polypharmacy and medication review.
Correct Answer: C
Rationale: According to the NCCN Older Adult Oncology
Guidelines, a CGA includes functional status, socioeconomic
issues, psychosocial distress, comorbidities, cognitive function,
nutritional status, polypharmacy, and medication review. Genetic
mutation testing and tumor markers are not components of a
CGA.
Item 3
Question: According to the NCCN Older Adult Oncology
Guidelines (version 1.2015), more than 60% of cancers in the
United States occur in people age _____ and older.
, A) 55
B) 60
C) 65
D) 70
Correct Answer: C
Rationale: The document explicitly states the threshold is age 65.
This age cutoff is used to define the older adult population for
cancer care guidelines, reflecting the demographic shift where
nearly half (46%) of cancer survivors are 70 or older.
Item 4
Question: A patient is receiving docetaxel and carboplatin
through a port. What is the best explanation for why a port was
placed rather than using a peripheral IV?
A) Both agents are classified as vesicants requiring central access.
B) The patient's age makes peripheral IVs unsafe.
C) Docetaxel is an irritant that can cause significant extravasation
reactions.
D) Carboplatin must be infused through a port to be effective.
Correct Answer: C
