PANCE ACTUAL EXAM 2026/2027 TEST | WITH COMPREHENSIVE
QUESTIONS AND VERIFIED ANSWERS | GRADED A+
What lab tests would you monitor in a patient with medullary thyroid cancer after treatment? -
ANSWER Calcitonin.
Patients with medullary thyroid cancer secrets calcitonin and CEA. After complete treatment, the
labs should show low levels of calcitoin or CEA
Testing for calcitonin and CEA can be use to diagnose and monitor medullary cancer
What antibodies will be seen in patients with hoshimoto's autoimmune disease? - ANSWER Anti-
thyroglobulin antibodies
What is the radionuclide imaging pattern noted during a thyroid scan in patients with subacute
thyroiditis? - ANSWER Low uptake of radioactive iodine
Acute inflammation is occurring during subacute thyroiditis, causing leakage of stored thyroid
hormone into the circulation. The thyroid is not metabolically active, and therefore there is low
radioactive iodine uptake on scan.
In patients with Pagets disease, what will happens to serum calcium, phosphorus, and alkaline
phosphate? - ANSWER Serum calcium and phosphorus are in normal range
Alkaline phosphate levels are elevated
What is the treatment of choice for pagets disease? - ANSWER Bisphophates**
New drug, that seems to be effective in the treatmen of paget is Tiludronate orally for 3months
Name the three cancers that are known to cause diabetes insipidus - ANSWER Metastatic lung and
breast cancer
cranipharyngiomas
Nephrogenic diabetes insipidus and central diabetes insipidus typically present in what type of
patients? - ANSWER young patients
The leision for pheochromocytoma is typically seen where? - ANSWER Adrenal medulla
,What you on the lab of a patient with pheochromocytoma? - ANSWER Elevated catecholamine
What is the best medication to use to treat hyperlipidemial during pregnancy? - ANSWER
Colesevelam (WelChol)
Its pregnancy category B
What is the most common cause of hypothyroidism? - ANSWER Autoimmune thyroiditis
With the use of Statins how much do u reduce LDL by doubling of the dose? - ANSWER 6%
What lipid drug is good for lowering LDL the most - ANSWER Enzetimide
What is faticious hypoglycemia - ANSWER This occurs when patients accidentally or on purpose self-
administer insulin or an insulin secretagogue. This occurs most commonly among health care
personnel, patients with diabetes or family members of those with diabetes, and people with a
history of other factitious diseases.
What lab sign will patient's with faticious hypoglycemia present? - ANSWER Increase insulin but
decrease in C-peptide
What labs will a patient with hypoglycemia due to beta insulinoma present - ANSWER Increase
insulin and increase C-peptide
unlike patients with faticious hypoglycemia
What tests can best determine whether the polyuria is resulting from primary polydipsia or some
form of diabetes insipidus? - ANSWER Water deprivation test
This test helps the practitioner determine if the patient can concentrate his/her urine with or
without becoming hyperosmolar. The patient is restricted from liquids and food during the test,
which must be done in a controlled environment.
What is the difference between the result of Water Deprivation Test in differentiating between
primary polydipsia or diabetes insipidus? - ANSWER A patient with PRIMARY POLYDIPSIA will be able
, to concentrate his/her urine without becoming hyperosmolar WHILE A patient with DIABETICS
INSIPIDUS will become hyperosmolar without concentrating the urine.
What genetic testing is done in family member to determine medullary thyroid carcinoma, multiple
endocrine neoplasias type 2A and 2B, phaeochromocytoma and parathyroid hyperplasia - ANSWER
ret proto-oncogene
this genetic test can also be done in patients with pheochromocytoma
Ret proto-oncogene genetic testing can be done in the family members of patients with what
diseases? - ANSWER Medullary thyroid cancer and/or Pheochromocytoma
Most patients require approximately ------- of glargine to reach therapeutic goals. - ANSWER 45 units
What is somogyi effect? - ANSWER It is when too much intermediate insulin is given at dinnertime.
Nocturnal hypoglycemia results in counter-regulatory hormones producing hyperglycemia.
Amiodarone is use to tx what? - ANSWER Atril fibrillation
What are the common unpleasant side effect of amiodarone? - ANSWER Hypo/ hyperthyroidism
What causes acromegaly? - ANSWER Pituitary adenoma secreting growth hormone
What are the symptoms of acromegaly? - ANSWER Coarse facial features, prognathism, widely
spaced teeth, and sleep apnea.
What are the lab finding of patient with hypothyroidism (Hoshimoto)? - ANSWER High serum TSH,
low serum total T4, low serum total T3, high thyroidal peroxidase antibodies, thyroglobulin, and TSH
receptor blocking autoantibodies
What are the lab findings of patient with hyperthyroidism (Graves disease)? - ANSWER Low serum
TSH, high serum total T4, and high thyroid stimulating antibodies
QUESTIONS AND VERIFIED ANSWERS | GRADED A+
What lab tests would you monitor in a patient with medullary thyroid cancer after treatment? -
ANSWER Calcitonin.
Patients with medullary thyroid cancer secrets calcitonin and CEA. After complete treatment, the
labs should show low levels of calcitoin or CEA
Testing for calcitonin and CEA can be use to diagnose and monitor medullary cancer
What antibodies will be seen in patients with hoshimoto's autoimmune disease? - ANSWER Anti-
thyroglobulin antibodies
What is the radionuclide imaging pattern noted during a thyroid scan in patients with subacute
thyroiditis? - ANSWER Low uptake of radioactive iodine
Acute inflammation is occurring during subacute thyroiditis, causing leakage of stored thyroid
hormone into the circulation. The thyroid is not metabolically active, and therefore there is low
radioactive iodine uptake on scan.
In patients with Pagets disease, what will happens to serum calcium, phosphorus, and alkaline
phosphate? - ANSWER Serum calcium and phosphorus are in normal range
Alkaline phosphate levels are elevated
What is the treatment of choice for pagets disease? - ANSWER Bisphophates**
New drug, that seems to be effective in the treatmen of paget is Tiludronate orally for 3months
Name the three cancers that are known to cause diabetes insipidus - ANSWER Metastatic lung and
breast cancer
cranipharyngiomas
Nephrogenic diabetes insipidus and central diabetes insipidus typically present in what type of
patients? - ANSWER young patients
The leision for pheochromocytoma is typically seen where? - ANSWER Adrenal medulla
,What you on the lab of a patient with pheochromocytoma? - ANSWER Elevated catecholamine
What is the best medication to use to treat hyperlipidemial during pregnancy? - ANSWER
Colesevelam (WelChol)
Its pregnancy category B
What is the most common cause of hypothyroidism? - ANSWER Autoimmune thyroiditis
With the use of Statins how much do u reduce LDL by doubling of the dose? - ANSWER 6%
What lipid drug is good for lowering LDL the most - ANSWER Enzetimide
What is faticious hypoglycemia - ANSWER This occurs when patients accidentally or on purpose self-
administer insulin or an insulin secretagogue. This occurs most commonly among health care
personnel, patients with diabetes or family members of those with diabetes, and people with a
history of other factitious diseases.
What lab sign will patient's with faticious hypoglycemia present? - ANSWER Increase insulin but
decrease in C-peptide
What labs will a patient with hypoglycemia due to beta insulinoma present - ANSWER Increase
insulin and increase C-peptide
unlike patients with faticious hypoglycemia
What tests can best determine whether the polyuria is resulting from primary polydipsia or some
form of diabetes insipidus? - ANSWER Water deprivation test
This test helps the practitioner determine if the patient can concentrate his/her urine with or
without becoming hyperosmolar. The patient is restricted from liquids and food during the test,
which must be done in a controlled environment.
What is the difference between the result of Water Deprivation Test in differentiating between
primary polydipsia or diabetes insipidus? - ANSWER A patient with PRIMARY POLYDIPSIA will be able
, to concentrate his/her urine without becoming hyperosmolar WHILE A patient with DIABETICS
INSIPIDUS will become hyperosmolar without concentrating the urine.
What genetic testing is done in family member to determine medullary thyroid carcinoma, multiple
endocrine neoplasias type 2A and 2B, phaeochromocytoma and parathyroid hyperplasia - ANSWER
ret proto-oncogene
this genetic test can also be done in patients with pheochromocytoma
Ret proto-oncogene genetic testing can be done in the family members of patients with what
diseases? - ANSWER Medullary thyroid cancer and/or Pheochromocytoma
Most patients require approximately ------- of glargine to reach therapeutic goals. - ANSWER 45 units
What is somogyi effect? - ANSWER It is when too much intermediate insulin is given at dinnertime.
Nocturnal hypoglycemia results in counter-regulatory hormones producing hyperglycemia.
Amiodarone is use to tx what? - ANSWER Atril fibrillation
What are the common unpleasant side effect of amiodarone? - ANSWER Hypo/ hyperthyroidism
What causes acromegaly? - ANSWER Pituitary adenoma secreting growth hormone
What are the symptoms of acromegaly? - ANSWER Coarse facial features, prognathism, widely
spaced teeth, and sleep apnea.
What are the lab finding of patient with hypothyroidism (Hoshimoto)? - ANSWER High serum TSH,
low serum total T4, low serum total T3, high thyroidal peroxidase antibodies, thyroglobulin, and TSH
receptor blocking autoantibodies
What are the lab findings of patient with hyperthyroidism (Graves disease)? - ANSWER Low serum
TSH, high serum total T4, and high thyroid stimulating antibodies
