TEST BANK
CLINICAL IMMUNOLOGY
AND SEROLOGY
Linda E. Miller, Christine Dorresteyn Stevens. (2021), Clinical immunology and serology.
,Table of Contents
I. Nature of the Immune System
1. Introduction to Immunity and the Immune System
2. Innate Immunity
3. Nature of Antigens and the Major Histocompatibility Complex
4. Adaptive Immunity
5. Antibody Structure and Function
6. Cytokines
7. The Complement System
II. Basic Immunological Procedures
8. Safety and Quality Management
9. Principles of Serological Testing
10. Precipitation and Agglutination Reactions
11. Labeled Immunoassays
12. Molecular Diagnostic Techniques
13. Flow Cytometry and Laboratory Automation
III. Immune Disorders
14. Hypersensitivity
15. Autoimmunity
16. Transplantation Immunology
17. Tumor Immunology
18. Immunoproliferative Diseases
19. Immunodeficiency Diseases
IV. Serological and Molecular Diagnosis of Infectious Disease
20. Serological and Molecular Detection of Bacterial Infections
21. Spirochete Diseases
22. Serological and Molecular Diagnosis of Parasitic and Fungal Infections
23. Serology and Molecular Detection of Viral Infections
24. Laboratory Diagnosis of HIV Infection
25. Immunization and Vaccines
Linda E. Miller, Christine Dorresteyn Stevens. (2021), Clinical immunology and serology.
,TEST BANK FOR CLINICAL IMMUNOLOGY AND
SEROLOGY A LABORATORY PERSPECTIVE, 5TH EDITION,
CHRISTINE DORRESTEYN STEVENS, LINDA E. MILLER
COMPLETE CHAPTERS
Chapter 1. Introduction to Immunity and the Immune System
Multiple Choice
1. Eosinophils are involved in the immune response against:
A. viruses.
B. intracellular bacteria.
C. parasites that cannot be phagocytized.
D. extracellular bacteria.
ANS: C
2. Which of the following are components of both innate and adaptive immune responses?
A. Immunoglobulins
B. T helper cells
C. Macrophages
D. B cells
ANS: C
3. The process by which leukocytes are attracted to a specific area by chemical messengers
is called: A. diapedesis.
B. degranulation.
C. chemotaxis.
D. opsonization.
Linda E. Miller, Christine Dorresteyn Stevens. (2021), Clinical immunology and serology.
,ANS: C
4. Which of the following is a characteristic of natural killer cells? A. They mature in the
thymus.
B. They are smaller than B and T cells.
C. They are a type of lymphocyte.
D. They are part of the adaptive immune system.
ANS: C
5. Which of the following best describes diapedesis?
A. Movement toward increasing concentrations of a cytokine
B. Attachment of immunoglobulin to target cells
C. Movement through blood vessel walls as cells exit the circulation
D. Engulfment of target cells ANS: C
6. The most effective phagocytic and antigen-presenting cell is the: A. neutrophil.
B. monocyte.
C. dendritic cell.
D. macrophage.
ANS: C
Linda E. Miller, Christine Dorresteyn Stevens. (2021), Clinical immunology and serology.
,7. Which of the following is characteristic of natural immunity? A. It involves memory.
B. T lymphocytes play a major role.
C. It involves specificity.
D. Mechanisms are always present and fully functional. ANS: D
8. All of the following cells are considered part of natural immunity EXCEPT: A.
eosinophils.
B. B lymphocytes.
C. monocytes.
D. neutrophils.
ANS: B
9. Where does the specific immune response to a foreign antigen mainly occur?
A. Lymph nodes
B. Blood
C. Bone marrow
D. Skin
ANS: A
10. Which white cell in the peripheral blood migrates into tissue to become a
macrophage? A. Eosinophil
B. Basophil
C. Neutrophil
D. Monocyte
Linda E. Miller, Christine Dorresteyn Stevens. (2021), Clinical immunology and serology.
,ANS: D
11. A white blood cell that is 16 to 18 micrometers in diameter, has a horseshoe-shaped
nucleus, and is capable of phagocytosis is a: A. neutrophil.
B. eosinophil.
C. basophil.
D. monocyte.
ANS: D
12. Pasteur's discovery that older bacterial cultures would not cause disease in chickens but
would protect them from subsequent infection with more virulent strains is an example of:
A. attenuated vaccine.
B. natural immunity.
C. passive immunity.
D. cross-immunity.
ANS: A
13. Antibodies are secreted by: A. plasma cells.
Linda E. Miller, Christine Dorresteyn Stevens. (2021), Clinical immunology and serology.
,B. B cells.
C. T cells.
D. dendritic cells.
ANS: A
14. Which of the following is characteristic of mucosal-associated lymphoid tissue? A.
It is one of the primary lymphoid organs.
B. It clears pathogens from the bloodstream.
C. It includes the tonsils and the appendix.
D. It includes the liver and spleen.
ANS: C
15. Acquired (adaptive) immunity can be characterized as: A. nonspecifically
activated.
B. immediately responsive.
C. neutrophil dependent.
D. involving memory.
ANS: D
Linda E. Miller, Christine Dorresteyn Stevens. (2021), Clinical immunology and serology.
, 16. Which of the following is NOT a characteristic of neutrophils?
A. Congregate in the marginating pool in blood vessels
B. Capable of diapedesis
C. Granules that become bright orange with Wright stain
D. Segmented nucleus ANS:
C
17. The function of NK cells is to: A. produce antibody.
B. phagocytize bacteria.
C. present antigen to T cells.
D. kill target cells such as tumor and virally infected cells. ANS: D
18. All of the following are involved in adaptive immunity EXCEPT: A. memory.
B. lymphocytes.
C. specificity.
D. neutrophils.
Linda E. Miller, Christine Dorresteyn Stevens. (2021), Clinical immunology and serology.
CLINICAL IMMUNOLOGY
AND SEROLOGY
Linda E. Miller, Christine Dorresteyn Stevens. (2021), Clinical immunology and serology.
,Table of Contents
I. Nature of the Immune System
1. Introduction to Immunity and the Immune System
2. Innate Immunity
3. Nature of Antigens and the Major Histocompatibility Complex
4. Adaptive Immunity
5. Antibody Structure and Function
6. Cytokines
7. The Complement System
II. Basic Immunological Procedures
8. Safety and Quality Management
9. Principles of Serological Testing
10. Precipitation and Agglutination Reactions
11. Labeled Immunoassays
12. Molecular Diagnostic Techniques
13. Flow Cytometry and Laboratory Automation
III. Immune Disorders
14. Hypersensitivity
15. Autoimmunity
16. Transplantation Immunology
17. Tumor Immunology
18. Immunoproliferative Diseases
19. Immunodeficiency Diseases
IV. Serological and Molecular Diagnosis of Infectious Disease
20. Serological and Molecular Detection of Bacterial Infections
21. Spirochete Diseases
22. Serological and Molecular Diagnosis of Parasitic and Fungal Infections
23. Serology and Molecular Detection of Viral Infections
24. Laboratory Diagnosis of HIV Infection
25. Immunization and Vaccines
Linda E. Miller, Christine Dorresteyn Stevens. (2021), Clinical immunology and serology.
,TEST BANK FOR CLINICAL IMMUNOLOGY AND
SEROLOGY A LABORATORY PERSPECTIVE, 5TH EDITION,
CHRISTINE DORRESTEYN STEVENS, LINDA E. MILLER
COMPLETE CHAPTERS
Chapter 1. Introduction to Immunity and the Immune System
Multiple Choice
1. Eosinophils are involved in the immune response against:
A. viruses.
B. intracellular bacteria.
C. parasites that cannot be phagocytized.
D. extracellular bacteria.
ANS: C
2. Which of the following are components of both innate and adaptive immune responses?
A. Immunoglobulins
B. T helper cells
C. Macrophages
D. B cells
ANS: C
3. The process by which leukocytes are attracted to a specific area by chemical messengers
is called: A. diapedesis.
B. degranulation.
C. chemotaxis.
D. opsonization.
Linda E. Miller, Christine Dorresteyn Stevens. (2021), Clinical immunology and serology.
,ANS: C
4. Which of the following is a characteristic of natural killer cells? A. They mature in the
thymus.
B. They are smaller than B and T cells.
C. They are a type of lymphocyte.
D. They are part of the adaptive immune system.
ANS: C
5. Which of the following best describes diapedesis?
A. Movement toward increasing concentrations of a cytokine
B. Attachment of immunoglobulin to target cells
C. Movement through blood vessel walls as cells exit the circulation
D. Engulfment of target cells ANS: C
6. The most effective phagocytic and antigen-presenting cell is the: A. neutrophil.
B. monocyte.
C. dendritic cell.
D. macrophage.
ANS: C
Linda E. Miller, Christine Dorresteyn Stevens. (2021), Clinical immunology and serology.
,7. Which of the following is characteristic of natural immunity? A. It involves memory.
B. T lymphocytes play a major role.
C. It involves specificity.
D. Mechanisms are always present and fully functional. ANS: D
8. All of the following cells are considered part of natural immunity EXCEPT: A.
eosinophils.
B. B lymphocytes.
C. monocytes.
D. neutrophils.
ANS: B
9. Where does the specific immune response to a foreign antigen mainly occur?
A. Lymph nodes
B. Blood
C. Bone marrow
D. Skin
ANS: A
10. Which white cell in the peripheral blood migrates into tissue to become a
macrophage? A. Eosinophil
B. Basophil
C. Neutrophil
D. Monocyte
Linda E. Miller, Christine Dorresteyn Stevens. (2021), Clinical immunology and serology.
,ANS: D
11. A white blood cell that is 16 to 18 micrometers in diameter, has a horseshoe-shaped
nucleus, and is capable of phagocytosis is a: A. neutrophil.
B. eosinophil.
C. basophil.
D. monocyte.
ANS: D
12. Pasteur's discovery that older bacterial cultures would not cause disease in chickens but
would protect them from subsequent infection with more virulent strains is an example of:
A. attenuated vaccine.
B. natural immunity.
C. passive immunity.
D. cross-immunity.
ANS: A
13. Antibodies are secreted by: A. plasma cells.
Linda E. Miller, Christine Dorresteyn Stevens. (2021), Clinical immunology and serology.
,B. B cells.
C. T cells.
D. dendritic cells.
ANS: A
14. Which of the following is characteristic of mucosal-associated lymphoid tissue? A.
It is one of the primary lymphoid organs.
B. It clears pathogens from the bloodstream.
C. It includes the tonsils and the appendix.
D. It includes the liver and spleen.
ANS: C
15. Acquired (adaptive) immunity can be characterized as: A. nonspecifically
activated.
B. immediately responsive.
C. neutrophil dependent.
D. involving memory.
ANS: D
Linda E. Miller, Christine Dorresteyn Stevens. (2021), Clinical immunology and serology.
, 16. Which of the following is NOT a characteristic of neutrophils?
A. Congregate in the marginating pool in blood vessels
B. Capable of diapedesis
C. Granules that become bright orange with Wright stain
D. Segmented nucleus ANS:
C
17. The function of NK cells is to: A. produce antibody.
B. phagocytize bacteria.
C. present antigen to T cells.
D. kill target cells such as tumor and virally infected cells. ANS: D
18. All of the following are involved in adaptive immunity EXCEPT: A. memory.
B. lymphocytes.
C. specificity.
D. neutrophils.
Linda E. Miller, Christine Dorresteyn Stevens. (2021), Clinical immunology and serology.
