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ANCC AGACNP BARKLEY REVIEW EXAM STUDY GUIDE 2026 COMPLETE QUESTIONS WITH CORRECT DETAILED ANSWERS || 100% GUARANTEED PASS RECENT VERSION

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ANCC AGACNP BARKLEY REVIEW EXAM STUDY GUIDE 2026 COMPLETE QUESTIONS WITH CORRECT DETAILED ANSWERS || 100% GUARANTEED PASS RECENT VERSION

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8/26/26, 11:01 PM ANCC AGACNP Barkley Review Flashcards | Quizlet



ANCC AGACNP Barkley Review
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Hemoglobin (Hgb) Main component of RBC's and the essential protein that combines with and
transports O2 to the body.


Males: 14-18 g/100 mL
Females: 12-16 g/100 mL


Hematocrit (Hct) Measures the percentage of a given volume of whole blood that is occupied by
erythrocytes: the amount of plasma to total RBC mass (RBC concentration).


Females: 37-47%
Males: 40-54%


Total Iron Binding Capacity (TIBC) Increased levels indicate iron deficiency (the greater their TIBC, the greater their
need for iron).; Decreased levels may indicate anemia, hemorrhage, hemolysis.


Normal: 250-450 mcg/dL


Serum iron Normal: 50-150 ug/dL


Mean Corpuscular Volume (MCV) Expression of the average volume and size of individual erythrocytes.


Normal: 80-100 um3
Microcytic = < 80, Normocytic = 80-100, and Macrocytic = > 100.


Mean Corpuscular Hemoglobin (MCH) Expression of the average amount and weight of Hgb contained in a single
erythrocyte.


Normal: 26-34 pg




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, 8/26/26, 11:01 PM ANCC AGACNP Barkley Review Flashcards | Quizlet


Mean Corpuscular Hemoglobin Concentration (MCHC) Expression of the average Hgb concentration or proportion of each RBC
occupied by Hgb as a percentage; more accurate measure than MCH.


Normal: 32-36%
Hypochromic < 32%, normochromic 32-36%, hyperchromic > 36%


Differential for low mean corpuscular volume (MCV) Iron deficiency anemia and thalassemia.


Differential for high mean corpuscular volume (MCV) B12 or folate deficiency (Megaloblastic anemia), alcoholism, liver failure, and drug
effects.


Differential for normal mean corpuscular volume (MCV) Anemia of chronic disease, sickle cell, renal failure, blood loss, and hemolysis.


Iron deficiency anemia is what type if anemia? Microcytic, Hypochromic.


Iron deficiency anemia A microcytic-hypochromic type of anemia characterized by iron deficiency that
affects the production of hemoglobin and is characterized by small red blood
cells containing low amounts of hemoglobin.


Signs and symptoms of iron deficiency anemia Usually few symptoms if Hct is greater than 30. As Hct decreases, symptoms
present: pica, dyspnea and mild fatigue with exercise, HA, palpitations, weakness,
tachycardia, postural hypotension, and pallor.


Laboratory findings in iron deficiency anemia Low Hgb, low Hct, low MCV, low MCHC, low RBC, low serum iron, low serum
ferritin (iron storage), high TIBC , *high RDW (red cell distribution width.


*Indicates there is a large difference in size from the largest to smallest RBC.


How is iron deficiency anemia treated Ferrous sulfate orally 300-325 mg 1-3 hour after meals. Do not take iron
supplements with antacids, it can interfere with absorption. Take with vitamin C
containing juices.


Increase iron intake: Raisins, green leafy vegetables, red meats, citrus products,
and iron-fortified bread and cereals.


What type of anemia is thalassemia Microcytic, hypochromic.


Thalassemia Genetic inherited disorders resulting in abnormal Hgb production and microcytic,
hypochromic anemia. Mostly found in Mediterranean, African American, Middle
Eastern, Indian, and Asian populations.


Etiology of thalassemia There is a decreased production of adult hemoglobin (Hb A); The global part of
Hb A has 4 protein sections called polypeptide chains - (1) two of these chains are
called alpha chains and are identical, (2) the other two are identical but different
from the alpha chains, called beta chains.


What is the most common type of thalassemia Beta thalassemia


What is the cause of beta thalassemia There is a reduction or absent production of beta globin chains.




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