Comprehensive Exam 2026 | Practice Questions, Answers & Detailed
x x x x x x x x
Rationales | Complete Nursing Study Guide
x x x x x x
Resource Features x
➢ Comprehensive final practice questions x x x
➢ Answers for self-assessment
x x
➢ Detailed rationales
x
➢ NCLEX-style questions x
➢ Clinical judgment practice
x x
➢ Prioritization questions x
, HESI Comprehensive Exam 2026 | Practice
x x x x x
Questions, Answers & Detailed Rationales |
x x x x x x
x Complete Nursing Study Guide x x x
Question 1 x
Enalapril maleate is prescribed for a hospitalized client. Which assessment
x x x x x x x x x
does the nurse perform as a priority before administering the medication?
x x x x x x x x x x x
A) Checking the client's blood pressure
x x x x x
B) Checking the client's peripheral pulses
x x x x x
C) Checking the most recent potassium level
x x x x x x
D) Checking the client's intake-and-output record for the last 24 hours
x x x x x x x x x x
Correct Answer: A x x
Rationale: Enalapril maleate is an angiotensin-converting enzyme (ACE)
x x x x x x x
inhibitor used to treat hypertension. One common side effect is postural
x x x x x x x x x x x
hypotension. Therefore the nurse would check the client's blood pressure
x x x x x x x x x x
immediately before administering each dose. Checking the client's
x x x x x x x x
peripheral pulses, the results of the most recent potassium level, and the
x x x x x x x x x x x x
intake and output for the previous 24 hours are not specifically associated
x x x x x x x x x x x x
with this medication.
x x x
Question 2 x
,A client is scheduled to undergo an upper gastrointestinal (GI) series, and the
x x x x x x x x x x x x
nurse provides instructions to the client about the test. Which statement by
x x x x x x x x x x x x
the client indicates a need for further instruction?
x x x x x x x x
A) "The test will take about 30 minutes."
x x x x x x x
B) "I need to fast for 8 hours before the test."
x x x x x x x x x x
C) "I need to drink citrate of magnesia the night before the test and give
x x x x x x x x x x x x x x
myself a Fleet enema on the morning of the test."
x x x x x x x x x x
D) "I need to take a laxative after the test is completed, because the liquid
x x x x x x x x x x x x x x
that I'll have to drink for the test can be constipating."
x x x x x x x x x x x
Correct Answer: C x x
Rationale: No special preparation is necessary before a GI series, except that
x x x x x x x x x x x
NPO (nothing by mouth) status must be maintained for 8 hours before the
x x x x x x x x x x x x x
test. An upper GI series involves visualization of the esophagus, duodenum,
x x x x x x x x x x x
and upper jejunum by means of the use of a contrast medium. It involves
x x x x x x x x x x x x x x
swallowing a contrast medium (usually barium), which is administered in a
x x x x x x x x x x x
flavored milkshake. Films are taken at intervals during the test, which takes
x x x x x x x x x x x x
about 30 minutes. After an upper GI series, the client is prescribed a laxative
x x x x x x x x x x x x x x
to hasten elimination of the barium. Barium that remains in the colon may
x x x x x x x x x x x x x
become hard and difficult to expel, leading to fecal impaction.
x x x x x x x x x x
Question 3 x
A nurse on the evening shift checks a primary health care provider's
x x x x x x x x x x x
prescriptions and notes that the dose of a prescribed medication is higher
x x x x x x x x x x x x
than the normal dose. The nurse calls the primary health care provider's
x x x x x x x x x x x x
, answering service and is told that the primary health care provider is off for
x x x x x x x x x x x x x x
the night and will be available in the morning. What should the nurse do
x x x x x x x x x x x x x x
next?
x
A) Call the nursing supervisor
x x x x
B) Ask the answering service to contact the on-call primary health care
x x x x x x x x x x x
provider
x
C) Withhold the medication until the primary health care provider can be
x x x x x x x x x x x
reached in the morning
x x x x
D) Administer the medication but consult the primary health care provider
x x x x x x x x x x
when he becomes available
x x x x
Correct Answer: B x x
Rationale: The nurse has a duty to protect the client from harm. A nurse who
x x x x x x x x x x x x x x
believes that a primary health care provider's prescription may be in error is
x x x x x x x x x x x x x
responsible for clarifying the prescription before carrying it out. Therefore
x x x x x x x x x x
the nurse would not administer the medication; instead, the nurse would
x x x x x x x x x x x
withhold the medication until the dose can be clarified. The nurse would not
x x x x x x x x x x x x x
wait until the next morning to obtain clarification. It is premature to call the
x x x x x x x x x x x x x x
nursing supervisor.
x x
Question 4 x
An emergency department (ED) nurse is monitoring a client with suspected
x x x x x x x x x x
acute myocardial infarction (MI) who is awaiting transfer to the coronary
x x x x x x x x x x x
intensive care unit. The nurse notes the sudden onset of premature
x x x x x x x x x x x
ventricular contractions (PVCs) on the monitor, checks the client's carotid
x x x x x x x x x x