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NU 150 - Galen - Pharm Test 3 Questions with Verified Correct Answers

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NU 150 - Galen - Pharm Test 3 Questions with
Verified Correct Answers
NSAIDs (actions)

Actions: Does not belong to steroid group of drugs Inhibit prostaglandin synthesis by

inhibiting an enzyme that triggers pain and inflammation.

NSAIDs (Therapeutic class)

Anti-inflammatory, Antipyretic, Analgesic

NSAIDs (examples)

ibuprofen (Motrin, Advil) indomethacin (Indocin) ketorolac (Toradol) naproxen (Naprosyn)

piroxicam (Feldene) celecoxib (Celebrex)

NSAIDs (uses)

Mild to moderate pain Rheumatoid Arthritis Osteoarthritis Dysmenorrhea

Morphine (uses)

Prototype or "model" opioid

Effective for moderately severe to severe pain Relief of severe cough (codeine) Pulmonary

Edema (morphine) Obstetric Analgesia (nubain) Pre-operative to lessen anxiety and sedate

Morphone (actions)

Actions on organs:

CNS: drowsiness, euphoria, sedation, mental clouding

Eye: pupil constriction (pinpoint pupil) (miosis)

Resp: depressed rate/depth of respirations and aggravation of asthma: suppress cough reflex

(codeine)

,GIT = ↓peristalsis in stomach & intestines; gastric, ↓pancreas/bile secretions; gallbladder

spasm (morphine) GUT = bladder contraction/spasm (urinary retention)

Skin: itching and rash

Morphone (adverse reactions)

Adverse reactions:

Physical dependence

Possible withdrawal symptoms upon discontinuing.

Opioid tolerance

Need to address the patient's pain because it takes priority over concerns about drug addiction

or physical dependence.

Symptoms of opioid withdrawal

Early signs

Yawning, perspiring, tearing, nasal drainage

Followed by:

Gooseflesh (goosebumps) • Abdominal cramps • Bone and muscle pain (rebound pain) • N/V,

diarrhea • Mydriasis (pupil dilation) • Intense craving for drug • Agitation • Elevated BP,

tachycardia • Seizures

Morphone (precautions)

Use cautiously in individuals with head injury, morbid obesity, and sleep apnea.

Precautions: Elderly: extreme confusion and hallucinations; smaller doses than younger adult

Undiagnosed abdominal pain Liver disease



Home use: Drug may cause drowsiness, dizziness • Caution with driving • Avoid alcohol •

Take med as directed • Explain how-to put-on patch

, Patient education on PCA machine:

Location of buttons • Regulation of dose and time interval • Assure machine will not deliver

dose until correct time • Pain relief should occur shortly after pushing button • Inform nurse if

pain not relieved after two doses

Naloxone (Narcan) (Use)

Complete or partial reverse of opioid effects after surgery or overdose

Naloxone (Narcan) (adverse reaction)

n/v, tachycardia, hypertension, return of postoperative pain, fever and dizziness

Hydrocodone (use)

severe pain

Hydrocodone (adverse reaction)

Sedation, sweating, headache, vertigo, lethargy, confusion, lightheadedness, nausea, vomiting

Meperidine (Demerol) opioid (use)

Acute moderate to severe pain, preoperative sedation, anesthetic adjunct

Meperidine (Demerol) opioid (adverse reaction)

Lightheadedness, constipation, dizziness, N/V, respiratory depression

Anticholinergic (glycopyrrolate) cholinergic blocking drug (uses)

Parasympathetic drug (rest and digestion)

Oral: peptic ulcer

Parenteral: in conjunction with anesthesia to reduce bronchial and oral secretions, to block

cardiac vagal

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