WGU D027 - Pathopharmacology
WGU D027 - Pathopharmacology
Study online at https://quizlet.com/_gx5is4
1. What is an indication for Alpha 1 Ag- Nasal congestion
onists?
2. What suffix is commonly associated -phrine
with Alpha 1 Agonists?
3. What is the mechanism of action Vasoconstricts blood vessels in the nostrils, leading
(MOA) of Alpha 1 Agonists? to increased air movement
4. What are some adverse effects Increased heart rate, increased blood pressure, in-
(ADRs) of Alpha 1 Agonists? creased alertness, insomnia
5. In which patients may Alpha 1 Ago- Patients with a cardiac history
nists cause exacerbation?
6. Alpha 1 and Beta 2 Receptor Sites Smooth muscle tissue of blood vessels, heart,
ureters, uterus, bronchioles, throughout nervous
system, and muscles that control pupil size.
7. Where are Alpha 2 receptor sites lo- Heart, smooth muscle tissue of blood vessels, and
cated? nervous system.
8. Where are Beta 1 receptor sites lo- Heart and juxtaglomerular cells of kidneys.
cated?
9. What is the indication for Alpha 2 Indicated for use as a reversal for alpha 2 agonists.
Antagonist?
10. What is the mechanism of action Inhibits norepi from binding with alpha 2 receptors,
(MOA) of Alpha 2 Antagonists? leading to an adrenergic response.
11. What is the suffix for Alpha 2 Antag- -ezole
onist drugs?
1 of 38
, WGU D027 - Pathopharmacology
WGU D027 - Pathopharmacology
Study online at https://quizlet.com/_gx5is4
12. What is an example of an Alpha 2 Atipamezole
Antagonist drug?
13. What are some adverse drug reac- Increased heart rate, central nervous stimulation,
tions (ADRs) of Alpha 2 Antagonists? tremors, insomnia.
14. How should Alpha 2 Antagonists be Administer slowly; if given too quickly as a reversal
administered? agent for dex, cardiac collapse can occur.
15. What is the drug name for Beta 1 Dobutamine
Agonists?
16. What condition are Beta 1 Agonists Cardiogenic shock
indicated for?
17. What is the mechanism of action Improves cardiac output by adrenergic effects
(MOA) of Beta 1 Agonists?
18. What effect do Beta 1 Agonists have Increased blood pressure due to arterial constriction
on blood pressure?
19. What effect do Beta 1 Agonists have Increased heart rate
on heart rate?
20. What are common adverse reac- Increased heart rate and blood pressure, tach-
tions (ADR) of Beta 1 Agonists? yarrhythmias
21. What is the drug name for Beta 2 Albuterol
Agonist?
22. What conditions are Beta 2 Agonists Chronic pulmonary conditions such as asthma and
indicated for? COPD.
23.
2 of 38
, WGU D027 - Pathopharmacology
WGU D027 - Pathopharmacology
Study online at https://quizlet.com/_gx5is4
What is the mechanism of action Relaxes smooth muscles within the airway, leading to
(MOA) of Beta 2 Agonists? bronchodilation.
24. What are some common adverse Increased heart rate, chest palpitations, tremors, and
drug reactions (ADRs) of Beta 2 Ag- restlessness.
onists?
25. In which conditions are Beta 2 Ago- Underlying chronic cardiac conditions such as hyper-
nists contraindicated? tension.
26. What is a key instruction for using Wait 1 minute between Albuterol MDI puffs and 5
Albuterol MDI? minutes between Albuterol and other medications.
27. Adrenergic State S/S Brain/CNS in heightened state: Pupils constrict, di-
gestive processes halted (decreased salivation/peri-
stalsis), Increased HR/BP, bronchodilation, bladder
relaxes, urinary sphincter contracts.
28. Cholinergic State S/S Parasympathetic = Neurological system in more
somnolent state: Pupils constrict, digestive process-
es occur (increased salivation/peristalsis), decreased
HR/BP, bronchoconstriction, bladder contraction,
urinary retention.
29. What is the suffix for Alpha 1 Antag- -osin
onists?
30. What is the drug name for an Alpha Tamsulosin
1 Antagonist?
31. What are the indications for Alpha 1 BPH, Insomnia, PTSD, HTN
Antagonists?
32. Cholinergic response triggered
3 of 38
, WGU D027 - Pathopharmacology
WGU D027 - Pathopharmacology
Study online at https://quizlet.com/_gx5is4
What is the mechanism of action
(MOA) for Alpha 1 Antagonists?
33. What are common adverse drug re- Decreased BP, dizziness, HA,
actions (ADR) of Alpha 1 Antago-
nists?
34. What is the drug name for the Alpha Clonidine
2 Agonist indicated for ADHD?
35. What are the indications for Alpha 2 ADHD, ETOH/Opiate withdrawal, chronic pain
Agonists?
36. What is the mechanism of action Cholinergic response triggered
(MOA) for Alpha 2 Agonists?
37. What are the adverse drug reactions Decreased HR/BP, Sedation
(ADRs) of Alpha 2 Agonists?
38. Beta 1 Antagonists A - N - Heart. Ex: Atenolol, Metoprolol.
39. Beta 2 Antagonist O - Z -Heart and lungs. Ex: Propanolol, Sotalol.
40. What type of medication is War- Vitamin K Antagonist
farin/Coumadin?
41. What is the goal INR range for pa- 2-4
tients on Warfarin?
42. What is the normal INR range? 0.8 - 1.2
43. Which antibiotic enhances the anti- Doxycycline
coagulant effect of Warfarin?
44. What is the antidote for Warfarin? Vitamin K
4 of 38
WGU D027 - Pathopharmacology
Study online at https://quizlet.com/_gx5is4
1. What is an indication for Alpha 1 Ag- Nasal congestion
onists?
2. What suffix is commonly associated -phrine
with Alpha 1 Agonists?
3. What is the mechanism of action Vasoconstricts blood vessels in the nostrils, leading
(MOA) of Alpha 1 Agonists? to increased air movement
4. What are some adverse effects Increased heart rate, increased blood pressure, in-
(ADRs) of Alpha 1 Agonists? creased alertness, insomnia
5. In which patients may Alpha 1 Ago- Patients with a cardiac history
nists cause exacerbation?
6. Alpha 1 and Beta 2 Receptor Sites Smooth muscle tissue of blood vessels, heart,
ureters, uterus, bronchioles, throughout nervous
system, and muscles that control pupil size.
7. Where are Alpha 2 receptor sites lo- Heart, smooth muscle tissue of blood vessels, and
cated? nervous system.
8. Where are Beta 1 receptor sites lo- Heart and juxtaglomerular cells of kidneys.
cated?
9. What is the indication for Alpha 2 Indicated for use as a reversal for alpha 2 agonists.
Antagonist?
10. What is the mechanism of action Inhibits norepi from binding with alpha 2 receptors,
(MOA) of Alpha 2 Antagonists? leading to an adrenergic response.
11. What is the suffix for Alpha 2 Antag- -ezole
onist drugs?
1 of 38
, WGU D027 - Pathopharmacology
WGU D027 - Pathopharmacology
Study online at https://quizlet.com/_gx5is4
12. What is an example of an Alpha 2 Atipamezole
Antagonist drug?
13. What are some adverse drug reac- Increased heart rate, central nervous stimulation,
tions (ADRs) of Alpha 2 Antagonists? tremors, insomnia.
14. How should Alpha 2 Antagonists be Administer slowly; if given too quickly as a reversal
administered? agent for dex, cardiac collapse can occur.
15. What is the drug name for Beta 1 Dobutamine
Agonists?
16. What condition are Beta 1 Agonists Cardiogenic shock
indicated for?
17. What is the mechanism of action Improves cardiac output by adrenergic effects
(MOA) of Beta 1 Agonists?
18. What effect do Beta 1 Agonists have Increased blood pressure due to arterial constriction
on blood pressure?
19. What effect do Beta 1 Agonists have Increased heart rate
on heart rate?
20. What are common adverse reac- Increased heart rate and blood pressure, tach-
tions (ADR) of Beta 1 Agonists? yarrhythmias
21. What is the drug name for Beta 2 Albuterol
Agonist?
22. What conditions are Beta 2 Agonists Chronic pulmonary conditions such as asthma and
indicated for? COPD.
23.
2 of 38
, WGU D027 - Pathopharmacology
WGU D027 - Pathopharmacology
Study online at https://quizlet.com/_gx5is4
What is the mechanism of action Relaxes smooth muscles within the airway, leading to
(MOA) of Beta 2 Agonists? bronchodilation.
24. What are some common adverse Increased heart rate, chest palpitations, tremors, and
drug reactions (ADRs) of Beta 2 Ag- restlessness.
onists?
25. In which conditions are Beta 2 Ago- Underlying chronic cardiac conditions such as hyper-
nists contraindicated? tension.
26. What is a key instruction for using Wait 1 minute between Albuterol MDI puffs and 5
Albuterol MDI? minutes between Albuterol and other medications.
27. Adrenergic State S/S Brain/CNS in heightened state: Pupils constrict, di-
gestive processes halted (decreased salivation/peri-
stalsis), Increased HR/BP, bronchodilation, bladder
relaxes, urinary sphincter contracts.
28. Cholinergic State S/S Parasympathetic = Neurological system in more
somnolent state: Pupils constrict, digestive process-
es occur (increased salivation/peristalsis), decreased
HR/BP, bronchoconstriction, bladder contraction,
urinary retention.
29. What is the suffix for Alpha 1 Antag- -osin
onists?
30. What is the drug name for an Alpha Tamsulosin
1 Antagonist?
31. What are the indications for Alpha 1 BPH, Insomnia, PTSD, HTN
Antagonists?
32. Cholinergic response triggered
3 of 38
, WGU D027 - Pathopharmacology
WGU D027 - Pathopharmacology
Study online at https://quizlet.com/_gx5is4
What is the mechanism of action
(MOA) for Alpha 1 Antagonists?
33. What are common adverse drug re- Decreased BP, dizziness, HA,
actions (ADR) of Alpha 1 Antago-
nists?
34. What is the drug name for the Alpha Clonidine
2 Agonist indicated for ADHD?
35. What are the indications for Alpha 2 ADHD, ETOH/Opiate withdrawal, chronic pain
Agonists?
36. What is the mechanism of action Cholinergic response triggered
(MOA) for Alpha 2 Agonists?
37. What are the adverse drug reactions Decreased HR/BP, Sedation
(ADRs) of Alpha 2 Agonists?
38. Beta 1 Antagonists A - N - Heart. Ex: Atenolol, Metoprolol.
39. Beta 2 Antagonist O - Z -Heart and lungs. Ex: Propanolol, Sotalol.
40. What type of medication is War- Vitamin K Antagonist
farin/Coumadin?
41. What is the goal INR range for pa- 2-4
tients on Warfarin?
42. What is the normal INR range? 0.8 - 1.2
43. Which antibiotic enhances the anti- Doxycycline
coagulant effect of Warfarin?
44. What is the antidote for Warfarin? Vitamin K
4 of 38
