NR507 Advanced Pathophysiology,
NR507 Advanced Pathophysiology
Study online at https://quizlet.com/_9c8fu7
1. How does blood flow Deoxygenated venous blood ’Sup. Vena Cava ’Right Atrium ’Tricuspid (AV)
through the heart? ’Empties into R. Ventricle (& it contracts) ’Blood ejected through Pulmonary
Valve ’Pulmonary Artery ’Lungs to be Oxygenated ’Pulmonary Veins ’L. Atrium
’Mitral (AV) ’L. Ventricle (pumps with each contraction) ’Aortic Valve ’Aorta ’
Body
2. What is systole? Contraction of the heart which pumps blood
3. Diastole Relaxation of the heart
4. What produces S1 closing of the heart valves
and S2 sound?
5. What produces S1? The mitral and tricuspid valves which close in systole
6. What produces S2 The closing of the aortic and pulmonic valves in diastole
sound?
7. What is cardiac out- the volume of blood pumped out by each ventricle per minute
put?
8. What is stroke vol- amount of blood pumped out by each ventricle with contraction
ume?
9. What determines stroke volume and heart rate
cardiac output?
10. What is preload? the degree of stretch on the heart before it contracts, related to ventricular
filling, end diastolic pressure, amount of blood entering the ventricle during
diastole
11. What is afterload? resistance left ventricle must overcome to circulate blood
12. What is contractility?
1 of 12
, NR507 Advanced Pathophysiology,
NR507 Advanced Pathophysiology
Study online at https://quizlet.com/_9c8fu7
Normal ability of muscle to contract at a given force for a given stretch. It is
independent of preload/afterload
13. Will sustained tachy- Decreased
cardia result in in-
creased or decreased
stroke volume?
14. What conditions can Ischemia, acidosis, cardiomyopathy
result in decreased
contractility?
15. What can cause in- HTN, pulmonary disease, damage to the aortic valve
crease afterload?
16. What has the most HTN
immediate effect on
afterload?
17. Why would hemor- Decreased volume of blood creates less resistance
rhaging cause de-
creased afterload?
18. What does increased Increases stroke volume, over time the body will be unable to compensate
preload do to stroke however
volume?
19. What can cause a de- Hemorrhage, dehydration...anything that causes reduced blood volume
creased preload?
20. What side of the Right (AKA Right sided HF)
heart is affected by
cor-pulmonale?
2 of 12
NR507 Advanced Pathophysiology
Study online at https://quizlet.com/_9c8fu7
1. How does blood flow Deoxygenated venous blood ’Sup. Vena Cava ’Right Atrium ’Tricuspid (AV)
through the heart? ’Empties into R. Ventricle (& it contracts) ’Blood ejected through Pulmonary
Valve ’Pulmonary Artery ’Lungs to be Oxygenated ’Pulmonary Veins ’L. Atrium
’Mitral (AV) ’L. Ventricle (pumps with each contraction) ’Aortic Valve ’Aorta ’
Body
2. What is systole? Contraction of the heart which pumps blood
3. Diastole Relaxation of the heart
4. What produces S1 closing of the heart valves
and S2 sound?
5. What produces S1? The mitral and tricuspid valves which close in systole
6. What produces S2 The closing of the aortic and pulmonic valves in diastole
sound?
7. What is cardiac out- the volume of blood pumped out by each ventricle per minute
put?
8. What is stroke vol- amount of blood pumped out by each ventricle with contraction
ume?
9. What determines stroke volume and heart rate
cardiac output?
10. What is preload? the degree of stretch on the heart before it contracts, related to ventricular
filling, end diastolic pressure, amount of blood entering the ventricle during
diastole
11. What is afterload? resistance left ventricle must overcome to circulate blood
12. What is contractility?
1 of 12
, NR507 Advanced Pathophysiology,
NR507 Advanced Pathophysiology
Study online at https://quizlet.com/_9c8fu7
Normal ability of muscle to contract at a given force for a given stretch. It is
independent of preload/afterload
13. Will sustained tachy- Decreased
cardia result in in-
creased or decreased
stroke volume?
14. What conditions can Ischemia, acidosis, cardiomyopathy
result in decreased
contractility?
15. What can cause in- HTN, pulmonary disease, damage to the aortic valve
crease afterload?
16. What has the most HTN
immediate effect on
afterload?
17. Why would hemor- Decreased volume of blood creates less resistance
rhaging cause de-
creased afterload?
18. What does increased Increases stroke volume, over time the body will be unable to compensate
preload do to stroke however
volume?
19. What can cause a de- Hemorrhage, dehydration...anything that causes reduced blood volume
creased preload?
20. What side of the Right (AKA Right sided HF)
heart is affected by
cor-pulmonale?
2 of 12
