ADVANCED PATHOPHYSIOLOGY Midterm REVIEW NR507
ADVANCED PATHOPHYSIOLOGY Midterm REVIEW NR507
Study online at https://quizlet.com/_88cwza
1. Glomeru- The glomerular-capillaries can trap blood-borne Ab & Ag-Ab complexes
lonephritis - Causes: PRIMARY: infection, drugs, toxins, vascular disorders, ischemia, immuno-
logic responses, free radicals. SECONDARY: DM, CHF, HIV, Lupus
Triggering event (infection)- Ag-Ab complex formation & deposition in glomerulus-
Activation of complement system & WBC infiltration- Glomerular injury & leakage-
Proteinuria/hematuria- edema, increase creat, azotemia, oliguria
OR
after glomerular injury & leakage- Coagulation cascade activation & FIbrin de-
position- Decreased capillary perfusion- decreased GFR- edema, increase creat,
azotemia, oliguria
2. S1 -Closing of mitral and tricuspid valve
- Beginning of systole
3. S2 - Closure of the aortic and pulmonic valve
- End of systole
4. Valvular stenosis the valve orifice is constricted and narrowed, impeding the forward flow of blood
and increasing the workload of the cardiac chamber proximal to the diseased valve.
Intraventricular or atrial pressure increases in the chamber to overcome resistance
to flow through the valve. Increased pressure causes the myocardium to work
harder, causing myocardial hypertrophy.
5. Aortic stenosis - LV hypertrophy
- L heart failure
- Pulmonary edema
- Exertional dyspnea
-Syncope
-Angina pectoris
- Systolic murmur
6. Mitral Stenosis
2026/08/25
, ADVANCED PATHOPHYSIOLOGY Midterm REVIEW NR507
ADVANCED PATHOPHYSIOLOGY Midterm REVIEW NR507
Study online at https://quizlet.com/_88cwza
- LA hypertrophy
-R ventricular failure
- Pulmonary edema
- Orthopnea
- Respiratory infections
- PH
-Edema
-Atypical chest pain
- Diastolic murmur
7. Stroke volume The volume of blood ejected per bear during systole
8. Cor Pulmonale right ventricular hypertrophy and heart failure due to pulmonary hypertension
9. Cardiac output HR x SV
-Normal= 5Lpm
-Preload, afterload, contractility, heart rate
10. Preload The volume inside the ventricle at the end of diastole
Determined by:
- Amount of venous blood returning to the ventricle during diastole
- The amount of blood in the ventricle after systole
11. Afterload The resistance to ejection of blood from the ventricle
total peripheral resistance (TPR)
Systemic vascular resistance (SVR)
12. Contractility sympathetic nervous system, epi and norepi) + inotropes
Acetylcholine released from vagus nerve - inotrope
2026/08/25
ADVANCED PATHOPHYSIOLOGY Midterm REVIEW NR507
Study online at https://quizlet.com/_88cwza
1. Glomeru- The glomerular-capillaries can trap blood-borne Ab & Ag-Ab complexes
lonephritis - Causes: PRIMARY: infection, drugs, toxins, vascular disorders, ischemia, immuno-
logic responses, free radicals. SECONDARY: DM, CHF, HIV, Lupus
Triggering event (infection)- Ag-Ab complex formation & deposition in glomerulus-
Activation of complement system & WBC infiltration- Glomerular injury & leakage-
Proteinuria/hematuria- edema, increase creat, azotemia, oliguria
OR
after glomerular injury & leakage- Coagulation cascade activation & FIbrin de-
position- Decreased capillary perfusion- decreased GFR- edema, increase creat,
azotemia, oliguria
2. S1 -Closing of mitral and tricuspid valve
- Beginning of systole
3. S2 - Closure of the aortic and pulmonic valve
- End of systole
4. Valvular stenosis the valve orifice is constricted and narrowed, impeding the forward flow of blood
and increasing the workload of the cardiac chamber proximal to the diseased valve.
Intraventricular or atrial pressure increases in the chamber to overcome resistance
to flow through the valve. Increased pressure causes the myocardium to work
harder, causing myocardial hypertrophy.
5. Aortic stenosis - LV hypertrophy
- L heart failure
- Pulmonary edema
- Exertional dyspnea
-Syncope
-Angina pectoris
- Systolic murmur
6. Mitral Stenosis
2026/08/25
, ADVANCED PATHOPHYSIOLOGY Midterm REVIEW NR507
ADVANCED PATHOPHYSIOLOGY Midterm REVIEW NR507
Study online at https://quizlet.com/_88cwza
- LA hypertrophy
-R ventricular failure
- Pulmonary edema
- Orthopnea
- Respiratory infections
- PH
-Edema
-Atypical chest pain
- Diastolic murmur
7. Stroke volume The volume of blood ejected per bear during systole
8. Cor Pulmonale right ventricular hypertrophy and heart failure due to pulmonary hypertension
9. Cardiac output HR x SV
-Normal= 5Lpm
-Preload, afterload, contractility, heart rate
10. Preload The volume inside the ventricle at the end of diastole
Determined by:
- Amount of venous blood returning to the ventricle during diastole
- The amount of blood in the ventricle after systole
11. Afterload The resistance to ejection of blood from the ventricle
total peripheral resistance (TPR)
Systemic vascular resistance (SVR)
12. Contractility sympathetic nervous system, epi and norepi) + inotropes
Acetylcholine released from vagus nerve - inotrope
2026/08/25
