Exam 3 Supplemental - Neuropathophysiology
Study online at https://quizlet.com/_hpl266
1. What condition is usually preceded by an Guillain-Barre
influenza-like illness where the affected in-
dividual has recovered prior to the onset of
symptoms?
2. Ascending paralysis is a clinical feature of Guillain-Barre
what condition?
3. What condition can be life threatening if Guillain-Barre
the intercostal muscles or the ANS is affect-
ed, usually causing respiratory paralysis?
4. What condition is characterized by recur- Chronic Inflammatory Demyelinating
ring periods of demyelinating and remyeli- Poly(radiculo)neuropathy
nating of peripheral neurons?
5. How long must symptoms be present for 2 months
a patient to be diagnosed with Chronic
Inflammatory Demyelinating Poly(radicu-
lo)neuropathy?
6. What PNS demyelinating condition will Chronic Inflammatory Demyelinating
have a positive response to steroids? Poly(radiculo)neuropathy
-Guillain Barre will not
7. Is Charcot-Marie-Tooth hereditary or an au- Hereditary
toimmune disorder?
8. Is Chronic Inflammatory Demyelinating Autoimmune
Poly(radiculo)neuropathy hereditary or an -T cells attack Schwann cells
autoimmune disorder?
9.
, Exam 3 Supplemental - Neuropathophysiology
Study online at https://quizlet.com/_hpl266
Is Guillain Barre Syndrome hereditary or an Autoimmune
autoimmune disorder? -T cells attack Schwann cells
10. What is the most common hereditary pe- Charcot-Marie-Tooth
ripheral neuropathy?
11. What is the most common type of CMT? CMT 1
12. Which PNS demyelinating disorder is a CMT
hereditary sensorimotor neuropathy?
13. Which autosomal dominant disorder is CMT 1
caused by a mutation of myelin protein
zero causing the Schwann cells to unravel?
14. Which two conditions form "onion-bulb" CMT (1) & Chronic Inflammatory Demyeli-
appearance of layers of Schwann cells nating Polyneuropathy
around the axon?
15. Which two conditions show histopatholog- CMT (1) & Chronic Inflammatory Demyeli-
ical evidence of recurrent demyelination nating Polyneuropathy
and remyelination of Schwann cells?
16. What is the classic sign of CMT 1? Inverted champagne bottle appearance
17. Distal muscle atrophy, sensory loss, and CMT 1
foot deformities are clinical features of
what disorder?
18. What autosomal dominant disorder is CMT 2
characterized by a mutation of the mito-
chondria leading to axonal damage/injury?
19. Which CMT is demyelinating? CMT 1
Study online at https://quizlet.com/_hpl266
1. What condition is usually preceded by an Guillain-Barre
influenza-like illness where the affected in-
dividual has recovered prior to the onset of
symptoms?
2. Ascending paralysis is a clinical feature of Guillain-Barre
what condition?
3. What condition can be life threatening if Guillain-Barre
the intercostal muscles or the ANS is affect-
ed, usually causing respiratory paralysis?
4. What condition is characterized by recur- Chronic Inflammatory Demyelinating
ring periods of demyelinating and remyeli- Poly(radiculo)neuropathy
nating of peripheral neurons?
5. How long must symptoms be present for 2 months
a patient to be diagnosed with Chronic
Inflammatory Demyelinating Poly(radicu-
lo)neuropathy?
6. What PNS demyelinating condition will Chronic Inflammatory Demyelinating
have a positive response to steroids? Poly(radiculo)neuropathy
-Guillain Barre will not
7. Is Charcot-Marie-Tooth hereditary or an au- Hereditary
toimmune disorder?
8. Is Chronic Inflammatory Demyelinating Autoimmune
Poly(radiculo)neuropathy hereditary or an -T cells attack Schwann cells
autoimmune disorder?
9.
, Exam 3 Supplemental - Neuropathophysiology
Study online at https://quizlet.com/_hpl266
Is Guillain Barre Syndrome hereditary or an Autoimmune
autoimmune disorder? -T cells attack Schwann cells
10. What is the most common hereditary pe- Charcot-Marie-Tooth
ripheral neuropathy?
11. What is the most common type of CMT? CMT 1
12. Which PNS demyelinating disorder is a CMT
hereditary sensorimotor neuropathy?
13. Which autosomal dominant disorder is CMT 1
caused by a mutation of myelin protein
zero causing the Schwann cells to unravel?
14. Which two conditions form "onion-bulb" CMT (1) & Chronic Inflammatory Demyeli-
appearance of layers of Schwann cells nating Polyneuropathy
around the axon?
15. Which two conditions show histopatholog- CMT (1) & Chronic Inflammatory Demyeli-
ical evidence of recurrent demyelination nating Polyneuropathy
and remyelination of Schwann cells?
16. What is the classic sign of CMT 1? Inverted champagne bottle appearance
17. Distal muscle atrophy, sensory loss, and CMT 1
foot deformities are clinical features of
what disorder?
18. What autosomal dominant disorder is CMT 2
characterized by a mutation of the mito-
chondria leading to axonal damage/injury?
19. Which CMT is demyelinating? CMT 1
