NR 546 Week 2 Neurotransmitters Midterm 1 | Agnes Jakes
2026 | Questions & Verified Answers | Latest Update |
Graded A+
1. What are some examples of client factors that can affect drug metabolism?
Age, genetics, liver function, and concurrent medications.
Diet, exercise, and hydration levels.
Mental health history and therapy type.
Only age and genetics.
2. A relative of a client diagnosed with depression asks the nurse about the
cause of the client's disorder. In responding, the nurse should be aware that
according to the biogenic amine theory, an individual with depression has a
deficiency in which neurotransmitters?
Dopamine and GABA
Aldosterone and Cortisone
Serotonin and Norepinephrine
Acetylcholine and Epinephrine
3. If a patient who smokes cigarettes is prescribed a medication metabolized by
CYP 1A2, what potential effect might this have on their treatment?
Increased metabolism of the medication, potentially reducing its
effectiveness.
No effect on the medication's metabolism.
Decreased metabolism of the medication, enhancing its effects.
Increased side effects due to slower metabolism.
,4. In the context of alcohol's mechanism of action, identify an effect of alcohol
on gamma-aminobutyric acid, or GABA.
Alcohol enhances the inhibitory effects of GABA at the GABA-A
receptor.
Only opioid drugs can enhance the effect of alcohol on GABA
Alcohol's effects on GABA are different from that of barbiturates
Only high doses of alcohol have an effect on GABA
5. If a patient taking Bupropion reports increased anxiety and insomnia, what
might be a recommended course of action?
Advise the patient to stop taking Bupropion immediately.
Switch to a medication that only affects serotonin.
Adjust the dosage or consider an alternative medication.
Increase the dosage to enhance effects.
6. Serotonin is responsible for:
Improving our mood
Regulating the gut
Regulating sleep
All of the above
7. Describe the potential psychological effects of low GABA levels in
individuals.
Low GABA levels enhance cognitive function.
Low GABA levels can lead to increased anxiety and mood disorders.
, Low GABA levels have no significant effects on mental health.
Low GABA levels improve sleep quality.
8. Describe the role of acetylcholine in the nervous system and its significance
in mental health.
Acetylcholine regulates mood and anxiety levels.
Acetylcholine is primarily responsible for the metabolism of
psychotropic medications.
Acetylcholine influences the levels of serotonin and dopamine.
Acetylcholine is crucial for muscle activation and plays a role in
memory and learning.
9. Serotonin is an important regulator of
learning
diurnal rhythms
mood
all of the above
10. What is the term used to describe the process of chemical transmission of
information between neurons?
Signal propagation
Synaptic transmission
Neurotransmission
Cellular communication
11. Some of the main side effects of Tricyclic Anti-depressants includes
, HTN, pain, confusion, HA, dizziness
orthostatic hypotension, increased risk of suicide, anticholinergic
effects
insomnia, weight loss, palpitations, HTN, arrhythmias
sexual dysfunction, weight gain, increased risk of suicide, serotonin
syndrome
12. If a patient presents with symptoms of anxiety and has been identified with
elevated norepinephrine levels, what would be the most appropriate initial
treatment approach?
Prescribe a norepinephrine reuptake inhibitor.
Suggest cognitive behavioral therapy only.
Prescribe a selective serotonin reuptake inhibitor.
Recommend lifestyle changes without medication.
13. The enzyme system responsible for the metabolism of most drugs is
alkaline phosphatase
cytochrome P450
active substrate
P-glycoprotein
14. What could too much dopamine in areas of the brain result in?
psychosis
delusions
blunted affect
hallucinations
2026 | Questions & Verified Answers | Latest Update |
Graded A+
1. What are some examples of client factors that can affect drug metabolism?
Age, genetics, liver function, and concurrent medications.
Diet, exercise, and hydration levels.
Mental health history and therapy type.
Only age and genetics.
2. A relative of a client diagnosed with depression asks the nurse about the
cause of the client's disorder. In responding, the nurse should be aware that
according to the biogenic amine theory, an individual with depression has a
deficiency in which neurotransmitters?
Dopamine and GABA
Aldosterone and Cortisone
Serotonin and Norepinephrine
Acetylcholine and Epinephrine
3. If a patient who smokes cigarettes is prescribed a medication metabolized by
CYP 1A2, what potential effect might this have on their treatment?
Increased metabolism of the medication, potentially reducing its
effectiveness.
No effect on the medication's metabolism.
Decreased metabolism of the medication, enhancing its effects.
Increased side effects due to slower metabolism.
,4. In the context of alcohol's mechanism of action, identify an effect of alcohol
on gamma-aminobutyric acid, or GABA.
Alcohol enhances the inhibitory effects of GABA at the GABA-A
receptor.
Only opioid drugs can enhance the effect of alcohol on GABA
Alcohol's effects on GABA are different from that of barbiturates
Only high doses of alcohol have an effect on GABA
5. If a patient taking Bupropion reports increased anxiety and insomnia, what
might be a recommended course of action?
Advise the patient to stop taking Bupropion immediately.
Switch to a medication that only affects serotonin.
Adjust the dosage or consider an alternative medication.
Increase the dosage to enhance effects.
6. Serotonin is responsible for:
Improving our mood
Regulating the gut
Regulating sleep
All of the above
7. Describe the potential psychological effects of low GABA levels in
individuals.
Low GABA levels enhance cognitive function.
Low GABA levels can lead to increased anxiety and mood disorders.
, Low GABA levels have no significant effects on mental health.
Low GABA levels improve sleep quality.
8. Describe the role of acetylcholine in the nervous system and its significance
in mental health.
Acetylcholine regulates mood and anxiety levels.
Acetylcholine is primarily responsible for the metabolism of
psychotropic medications.
Acetylcholine influences the levels of serotonin and dopamine.
Acetylcholine is crucial for muscle activation and plays a role in
memory and learning.
9. Serotonin is an important regulator of
learning
diurnal rhythms
mood
all of the above
10. What is the term used to describe the process of chemical transmission of
information between neurons?
Signal propagation
Synaptic transmission
Neurotransmission
Cellular communication
11. Some of the main side effects of Tricyclic Anti-depressants includes
, HTN, pain, confusion, HA, dizziness
orthostatic hypotension, increased risk of suicide, anticholinergic
effects
insomnia, weight loss, palpitations, HTN, arrhythmias
sexual dysfunction, weight gain, increased risk of suicide, serotonin
syndrome
12. If a patient presents with symptoms of anxiety and has been identified with
elevated norepinephrine levels, what would be the most appropriate initial
treatment approach?
Prescribe a norepinephrine reuptake inhibitor.
Suggest cognitive behavioral therapy only.
Prescribe a selective serotonin reuptake inhibitor.
Recommend lifestyle changes without medication.
13. The enzyme system responsible for the metabolism of most drugs is
alkaline phosphatase
cytochrome P450
active substrate
P-glycoprotein
14. What could too much dopamine in areas of the brain result in?
psychosis
delusions
blunted affect
hallucinations
