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CRCM BSA AML FRAUD DETECTION REPORTING REQUIREMENTS SAR CTR FILING PROCEDURES PRACTICE TEST PAPER

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CRCM BSA AML FRAUD DETECTION REPORTING REQUIREMENTS SAR CTR FILING PROCEDURES PRACTICE TEST PAPER

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CRCM BSA AML FRAUD DETECTION
REPORTING REQUIREMENTS SAR CTR
FILING PROCEDURES PRACTICE TEST
PAPER

●● What is required for the diagnosis of ALL/AML?
Answer: bone marrow biopsy


●● What are some poor prognosis risk factors for ALL?
Answer: - Philadelphia chromosome
- age <1 or >10 years old
- t(4:11)
- TP53
- monosomy of chromosome 7


●● What defines remission in ALL?
Answer: continuous complete response for >5 years


●● What ALL patients will receive CNS prophylaxis?
Answer: all of the patients will get it

, ●● What are the options for CNS therapy for ALL?
Answer: - cranial irradiation
- intrathecal therapy (MTX, cytarabine, corticosteroid)**
- high dose systemic chemotherapy


●● What is the backbone of induction therapy for ALL?
Answer: - vincristine
- cyclophosphamide
- anthracycline
- steroids


●● What chemotherapy agent should never be given intrathecally
because it can be fatal (always dispensed in IV minibag)?
Answer: vincristine


●● What are the common ADE associated with vincristine?
Answer: - neurotoxicity
- neuropathy
- extravasation (warm compress)


●● What are the toxicities associated with cyclophosphamide?
Answer: - myelosuppression

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