TEST BANK FOR BASIC AND CLINICAL PHARMACOLOGY 16TH EDITION KATZUNG’S TESTBANK /ALL CHS 1- 66/COMPLETE GUIDE

TEST BANK FOR BASIC AND CLINICAL PHARMACOLOGY
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16TH EDITION KATZUNG’S TESTBANK /ALL CHS 1-
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66/COMPLETE GUIDE 2024-2025
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,CH 1. Introduction: The Nature of Drugs & Drug Development & Regulation
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1. A nurse working in radiology administers iodine to a hospital client who is
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having a computed tomography (CT) scan. The nursing attendant working
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on the oncology unit administers chemotherapy to hospital clients who have
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cancer. At the Public Health Department, a nursing attendant administers a
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measles-mumps-rubella (MMR) vaccine to a 14-month-old child as a
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routine immunization. Which branch of pharmacology best describes the
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actions of all three
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nursing attendants? bg




A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
ACCURATE CHOICE:- bg B
Reasoning :->>>>>> bg




Pharmacology is the study of the biologic effects of chemicals. Nursing bg bg bg bg bg bg bg bg bg bg




attendants are involved with clinical pharmacology or pharmacotherapeutics,
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which is a branch of pharmacology that deals with the uses of drugs to treat,
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prevent, and diagnose disease. The radiology nursing attendant is
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administering a drug to help diagnose a disease. The oncology nursing
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attendant is administering a drug to help treat a disease. Pharmacoeconomics
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includes any costs involved in drug therapy.
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Pharmacodynamics involves how a drug affects the body and bg bg bg bg bg bg bg bg




pharmacokinetics is how the body acts on the body. bg bg bg bg bg bg bg bg




2. When involved in phase III drug evaluation studies, what
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responsibilities would the nursing attendant have?
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A) Working with animals who are given experimental drugs bg bg bg bg bg bg bg




B) Choosing appropriate hospital clients to be involved in the drug study
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C) Monitoring and observing hospital clients closely for adverse effects bg bg bg bg bg bg bg b g




D) Conducting research to determine effectiveness of the drug bg bg bg bg bg bg bg

,ACCURATE CHOICE:-
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Reasoning:->>>>>>

Phase III studies involve use of a drug in a vast clinical population in which
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hospital clients are asked to record any symptoms they experience while
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taking the drugs. Nursing attendants may be responsible for helping collect
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and analyzethe information to be shared with the Food and Drug
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Administration (FDA)but would not conduct research independently
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because nursing attendants donot prescribe medications. Use of animals in
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drug testing is done in the preclinical trials. Select hospital clients who are
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involved in phase II studies to participate in studies where the participants
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have the disease the drug is intended to treat. These hospital clients are
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monitored closely for drug action and adverse effects. Phase I studies
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involve healthy human volunteers who are usually paid for their
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participation. Nursing attendants may observe for
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adverse effects and toxicity. bg bg bg




3. A physician has ordered intramuscular (IM) injections of morphine, a
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narcotic, every 4 hours as needed for pain in a motor vehicle accident victim.
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The nursing attendant is aware this drug has a high abuse potential. Under
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what category would morphine be classified?
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A) Schedule I bg




B) Schedule II bg




C) Schedule III bg




D) Schedule IV bg




ACCURATE CHOICE:-
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Reasoning:->>>>>>

Narcotics with a high abuse potential are classified as Schedule II drugs
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because of severe dependence liability. Schedule I drugs have high abuse
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potential and no accepted medical use. Schedule III drugs have a lesser
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abuse potential than II and an accepted medical use. Schedule IV drugs have
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low abuse potential and limited dependence liability.
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4. What concept is considered when generic drugs are substituted for brand
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name drugs?
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A) Bioavailability

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B) Critical concentration bg




C) Distribution
D) Half-life
ACCURATE CHOICE:-A
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Reasoning:->>>>>>

Bioavailability is the portion of a dose of a drug that reaches the systemic bg bg bg bg bg bg bg bg bg bg bg bg bg




circulation and is available to act on body cells. Binders used in a generic
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drug may not be the same as those used in the brand name drug. Therefore,
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the way the body breaks down and uses the drug may differ, which may
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eliminate a generic drug substitution. Critical concentration is the amount ofa
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drug that is needed to cause a therapeutic effect and should not differ
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between generic and brand name medications. Distribution is the phase of
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pharmacokinetics, which involves the movement of a drug to the bodys
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tissues and is the same in generic and brand name drugs. A drugs half-life is
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the time it takes for the amount of drug to decrease to half the peak level,
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which should not change when substituting a generic medication.
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5. Anursing attendant is assessing the hospital clients home medication use. After
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listening to the hospital client list current medications, the nursing attendant
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askswhat priority question?
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A) Do you take any generic medications?
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B) Are any of these medications orphan drugs?
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C) Are these medications safe to take during pregnancy?
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D) Do you take any over-the-counter medications?
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ACCURATE CHOICE:-
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Reasoning:->>>>>>

It is important for the nursing attendant to specifically question use of over-
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the-counter medications because hospital clients may not consider them
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important. The hospital client is unlikely to know the meaning of orphan
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drugs unless they too are primary health care providers. Safety during
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pregnancy, use of a genericmedication, or classification of orphan drugs are
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things the hospital client would be unable to answer but could be found in
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reference books if the nursing attendant wishes to research them.
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