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HESI Entrance Exam Questions & Answers 2026/2027 Latest Comprehensive Review (Rationales)

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Prepare for the HESI Entrance Exam with this 2026/2027 comprehensive review, featuring 839 questions and rationales. Master key topics including Basic Chemistry, Anatomy, Homeostasis & Disease, and Cellular Biology to strengthen your fundamental science and verbal ability for nursing school admission. This resource offers detailed explanations to support your in-depth study and exam readiness.

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HESI ENTRANCE EXAM QUESTIONS & ANSWERS 2026-2027 | LATEST CO… EXAM

P R O F E S S I O N A L P R A C T I C E M AT E R I A L S




HESI Entrance Exam
Questions & Answers
2026-2027 | Latest
Comprehensive Review
(Rationales)

Verified Answers Exam Ready With Rationales
839 QUESTIONS




DOCUMENT OVERVIEW
This comprehensive review document provides 839 HESI Entrance Exam questions and their correct
answers, each accompanied by detailed rationales and visuals, covering fundamental science and
verbal ability. It is suitable for in-depth study, rapid review, and direct preparation for certification
exams by offering complete question-answer-explanation sets. This resource serves as a complete
study guide for aspiring nursing students.




CONTENTS
• Basic Chemistry & Atomic Structure • Body Elements & Molecules
• pH and Homeostasis • Anatomy: Body Organization & Planes
• Anatomical Terminology • Planes of the Body
• Homeostasis & Disease • Cellular Biology & Processes
• Cellular Components • Body Cavities & Membranes
Page 1

,• Endocrine System • Endocrine System: Hormones & Glands
• Systemic Diseases • Cellular Respiration & Metabolism
• Transport Across Membranes • Cell Division
• Water Properties & pH • Water Properties
• Digestive System: Anatomy & Physiology • Digestive System: Secretions & Enzymes
• Digestive System: Organs & Processes • Urinary System & Excretion
• Urinary System: Function & Regulation • Urinary System: Anatomy & Waste
• Male Reproductive System • Reproductive System: Male
• Female Reproductive System & Pregnancy • Reproductive System: Female
• Metric & Imperial Conversions • Vocabulary & Word Usage
• Tissue Types • Integumentary System
• Skeletal System: Bones & Joints • Skeletal System: Axial
• Skeletal System: Appendicular • Muscular System
• Muscular System: Function • Nervous System: Structure & Function
• Nervous System: Neurons & Divisions • Cardiovascular System: Blood
• Cardiovascular System: Heart & Circulation • Respiratory System
• Roman Numerals



E XA M Q U EST I O N S


Q1 QUESTION 1 OF 839
What are the most abundant elements of the human body?
CORRECT ANSWER

Carbon, Hydrogen, Oxygen, Nitrogen




Page 2

, RATIONALE
Carbon, hydrogen, oxygen, and nitrogen are the most abundant elements because they form the backbone
of organic molecules like carbohydrates, lipids, proteins, and nucleic acids, which constitute the bulk of
cellular structure and function. This reflects the fundamental principles of organic chemistry and
biochemistry that govern biological composition.



Q2 QUESTION 2 OF 839
90% of the human body is composed of just four elements which are:
CORRECT ANSWER

Carbon, Hydrogen, Oxygen, Nitrogen

RATIONALE
These four elements form the backbone of organic molecules like proteins, carbohydrates, lipids, and
nucleic acids, which constitute the vast majority of cellular mass and biological processes. This principle
highlights the fundamental building blocks of life and their biochemical significance.



Q3 QUESTION 3 OF 839
Subatomic particles are:
CORRECT ANSWER

Protons (positive), Neutrons (neutral) and Electrons (negative)

RATIONALE
Subatomic particles are the fundamental components of atoms, defined by their electric charge: protons are
positively charged, neutrons are neutral, and electrons carry a negative charge. This charge distribution
dictates atomic structure and chemical behavior.



Q4 QUESTION 4 OF 839
The number of protons and neutrons is called:
CORRECT ANSWER

Mass Number




Page 3

, RATIONALE
The mass number represents the total count of protons and neutrons within an atom's nucleus, defining its
atomic mass. This principle is central to understanding isotopes and atomic composition.



Q5 QUESTION 5 OF 839
What is a molecule?
CORRECT ANSWER

Atoms bonded together to form a chemical unit

RATIONALE
A molecule is the smallest particle of a substance that retains all chemical and physical properties of the
substance, formed when two or more atoms are chemically bonded together. This represents the
fundamental unit of a chemical compound.



Q6 QUESTION 6 OF 839
What are ions?
CORRECT ANSWER

Particle that is electrically charged because it has gained or lost one or more eletrons

RATIONALE
Ions are atoms or molecules that possess a net electrical charge due to the unequal number of protons and
electrons, specifically arising from the gain or loss of electrons. This gain or loss creates a charge imbalance,
defining the particle as an ion.



Q7 QUESTION 7 OF 839
hydrophilic means
CORRECT ANSWER

water-living




Page 4

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