BMSC 230 - Module 3-Questions and
Answers.
Biological function of gluconeogenesis - Answer To assist in maintaining adequate blood
glucose levels
Where gluconeogenesis occurs in animals - Answer Primarily liver, but also kidneys
Basic formula for gluconeogenesis - Answer 2 pyruvate + 4 ATP + 2 GTP + 2 NADH + 2 H +
6H2O = Glucose + 4 ADP + 2 GDP + 6 Pi + 2 NAD+
CHECK NOTES FOR A GLUCONEOGENESIS FILL IN SHEET AFTER THESE FLASHCARDS pls - Answer
.
Role of lactate in gluconeogenesis - Answer Lactate to be converted to pyruvate, in order to
start gluconeogenesis
Role of glycerol in gluconeogenesis - Answer Fats can be broken down into glycerol and fatty
acids, the glycerol is converted into dihydroxyacetone phosphate in the liver
Unique Steps of gluconeogenesis - Answer 1. Pyruvate -> oxoloacetate
2. Fructose-6-P -> fructose-1,6-biP
3. G6P -> glucose
How is oxoloacetate transported out of the mitochondria? - Answer 1. Oxoloacetate is
converted into malate in the mitochondria, producing NAD+ from an NADH
2. The malate is transported out of the mitochondria
3. The malate is converted back into oxoloacetate, producing an NADH
_____ high-transfer-potential phosphoryl groups are spent synthesizing pyruvate into glucose -
Answer 6
The major point of regulation in both glycolysis and gluconeogenesis - Answer The exchange
back and forth between fructose-1,6-biphosphate and fructose-6-phosphate
Effects of AMP in the liver balance between the two processes - Answer AMP represents low
energy, so it activates PFK while inhbiting fructose-1,6-biphosphate, which results in more
glycolysis
Answers.
Biological function of gluconeogenesis - Answer To assist in maintaining adequate blood
glucose levels
Where gluconeogenesis occurs in animals - Answer Primarily liver, but also kidneys
Basic formula for gluconeogenesis - Answer 2 pyruvate + 4 ATP + 2 GTP + 2 NADH + 2 H +
6H2O = Glucose + 4 ADP + 2 GDP + 6 Pi + 2 NAD+
CHECK NOTES FOR A GLUCONEOGENESIS FILL IN SHEET AFTER THESE FLASHCARDS pls - Answer
.
Role of lactate in gluconeogenesis - Answer Lactate to be converted to pyruvate, in order to
start gluconeogenesis
Role of glycerol in gluconeogenesis - Answer Fats can be broken down into glycerol and fatty
acids, the glycerol is converted into dihydroxyacetone phosphate in the liver
Unique Steps of gluconeogenesis - Answer 1. Pyruvate -> oxoloacetate
2. Fructose-6-P -> fructose-1,6-biP
3. G6P -> glucose
How is oxoloacetate transported out of the mitochondria? - Answer 1. Oxoloacetate is
converted into malate in the mitochondria, producing NAD+ from an NADH
2. The malate is transported out of the mitochondria
3. The malate is converted back into oxoloacetate, producing an NADH
_____ high-transfer-potential phosphoryl groups are spent synthesizing pyruvate into glucose -
Answer 6
The major point of regulation in both glycolysis and gluconeogenesis - Answer The exchange
back and forth between fructose-1,6-biphosphate and fructose-6-phosphate
Effects of AMP in the liver balance between the two processes - Answer AMP represents low
energy, so it activates PFK while inhbiting fructose-1,6-biphosphate, which results in more
glycolysis
