BMSC 230 -METABOLISM- MODULES 8-
13 Test Questions and Correct Answers.
how are fatty acids degraded - Answer B-oxidation
What is B-oxidation? - Answer a repetitive process where long-chain fatty acids are degraded
to acetyl CoA, depending on the length of the fatty acid.
in b-oxidation the acetyl CoA produced can directly enter which cycle - Answer citric acid cycle
Where does B-oxidation occur? - Answer mitochondrial matrix
during each cycle of b-oxidation ________ and _______ are produced - Answer NADH, FADH2
During each cycle of β-oxidation, NADH and FADH2 are produced and they can donate their
electrons to the _____________ to generate ______ - Answer electron transport chain, ATP
Fatty acids have a long _______ chain with a ___________ group on the end - Answer
hydrocarbon, carboxylic acid
The length of fatty acids varies, with commonly occurring ones ranging from _____ carbons in
length - Answer 12-20
The hydrocarbon chains are __________ in nature - Answer non-polar
The non-polar nature of hydrocarbons can induce a kink in hydrocarbon chain, which affects
their physical properties such as ______________________ of the fatty acid. - Answer
lowering the melting point
Most double bonds in fatty acids are in the ____ -configuration, which means that the
substituents on each side of the double bond are on the ______ side. - Answer cis, same
Carbons 2 & 3 are referred to as ??? - Answer a and B carbons
The carbon atoms in fatty acids are usually numbered beginning with the _________ carbon
and it is assigned in position ______ - Answer carboxyl terminal, 1
, The position of the double bond is denoted in the systematic name of the fatty acid with a Δ
sign accompanied by a number indicating the position of the first carbon that is part of the
double bond. For example, the fatty acid shown below in Figure 8-2a, which is commonly called
oleate, has a systematic name 18:1(Δ9) cis-9-octadecenoic acid. 18 indicates the number of
carbons in the fatty acid; 18:1 refers to an 18 carbon long fatty acid with one double bond; the
Δ9 indicates the position of the double bond (between carbons 9 and 10); and the cis
configuration is included in the name to indicate that relative configuration of the substituents
on the two carbons participating in the double bond. Panel b in Figure 8-2 shows an omega-3
fatty acid which is 20 carbons long and has 5 double bonds. A different nomenclature system
numbers carbons from the methyl carbon end, which is called the omega (ω) carbon. Thus,
omega-3 - Answer
How many rounds of fatty acid synthesis are required to form palmitate? - Answer 7
True or False?
Pentose phosphate pathway, and the transport of acetyl CoA in the form of citrate to the cytosol
from the mitochondria are the two sources of NADPH required for fatty acid synthesis. - Answer
True
Which is the correct repetitive reaction sequence for fatty acid synthesis? - Answer
Condensation, reduction, dehydration, reduction.
Which of the following statements about acetyl CoA carboxylase are true?
A) It has higher activity when it forms long filaments.
B) It is phosphorylated by protein kinase A.
C) Insulin stimulates its activity.
D) When it is phosphorylated it has lower activity.
E) It catalyzes the first committed step in fatty acid synthesis.
F) The product of the reaction it catalyzes is malonyl ACP. - Answer A) C) D) E)
Fatty acids can be used for a variety of important biological functions. Which of the below is
NOT one of these?Can be used to supply carbons for ketone body synthesis.
A) Can be used to supply carbons for ketone body synthesis.
B)Can be used to supply carbons for glucose synthesis.
C) Are components of membranes.
D) Are precursors for signalling molecules. - Answer B) Can be used to supply carbons for
glucose synthesis.
How does acetyl CoA get from the mitochondria to the cytosol so it can be used in fatty acid
synthesis?
A) It is directly transported by a specialized shuttle system.
13 Test Questions and Correct Answers.
how are fatty acids degraded - Answer B-oxidation
What is B-oxidation? - Answer a repetitive process where long-chain fatty acids are degraded
to acetyl CoA, depending on the length of the fatty acid.
in b-oxidation the acetyl CoA produced can directly enter which cycle - Answer citric acid cycle
Where does B-oxidation occur? - Answer mitochondrial matrix
during each cycle of b-oxidation ________ and _______ are produced - Answer NADH, FADH2
During each cycle of β-oxidation, NADH and FADH2 are produced and they can donate their
electrons to the _____________ to generate ______ - Answer electron transport chain, ATP
Fatty acids have a long _______ chain with a ___________ group on the end - Answer
hydrocarbon, carboxylic acid
The length of fatty acids varies, with commonly occurring ones ranging from _____ carbons in
length - Answer 12-20
The hydrocarbon chains are __________ in nature - Answer non-polar
The non-polar nature of hydrocarbons can induce a kink in hydrocarbon chain, which affects
their physical properties such as ______________________ of the fatty acid. - Answer
lowering the melting point
Most double bonds in fatty acids are in the ____ -configuration, which means that the
substituents on each side of the double bond are on the ______ side. - Answer cis, same
Carbons 2 & 3 are referred to as ??? - Answer a and B carbons
The carbon atoms in fatty acids are usually numbered beginning with the _________ carbon
and it is assigned in position ______ - Answer carboxyl terminal, 1
, The position of the double bond is denoted in the systematic name of the fatty acid with a Δ
sign accompanied by a number indicating the position of the first carbon that is part of the
double bond. For example, the fatty acid shown below in Figure 8-2a, which is commonly called
oleate, has a systematic name 18:1(Δ9) cis-9-octadecenoic acid. 18 indicates the number of
carbons in the fatty acid; 18:1 refers to an 18 carbon long fatty acid with one double bond; the
Δ9 indicates the position of the double bond (between carbons 9 and 10); and the cis
configuration is included in the name to indicate that relative configuration of the substituents
on the two carbons participating in the double bond. Panel b in Figure 8-2 shows an omega-3
fatty acid which is 20 carbons long and has 5 double bonds. A different nomenclature system
numbers carbons from the methyl carbon end, which is called the omega (ω) carbon. Thus,
omega-3 - Answer
How many rounds of fatty acid synthesis are required to form palmitate? - Answer 7
True or False?
Pentose phosphate pathway, and the transport of acetyl CoA in the form of citrate to the cytosol
from the mitochondria are the two sources of NADPH required for fatty acid synthesis. - Answer
True
Which is the correct repetitive reaction sequence for fatty acid synthesis? - Answer
Condensation, reduction, dehydration, reduction.
Which of the following statements about acetyl CoA carboxylase are true?
A) It has higher activity when it forms long filaments.
B) It is phosphorylated by protein kinase A.
C) Insulin stimulates its activity.
D) When it is phosphorylated it has lower activity.
E) It catalyzes the first committed step in fatty acid synthesis.
F) The product of the reaction it catalyzes is malonyl ACP. - Answer A) C) D) E)
Fatty acids can be used for a variety of important biological functions. Which of the below is
NOT one of these?Can be used to supply carbons for ketone body synthesis.
A) Can be used to supply carbons for ketone body synthesis.
B)Can be used to supply carbons for glucose synthesis.
C) Are components of membranes.
D) Are precursors for signalling molecules. - Answer B) Can be used to supply carbons for
glucose synthesis.
How does acetyl CoA get from the mitochondria to the cytosol so it can be used in fatty acid
synthesis?
A) It is directly transported by a specialized shuttle system.
