Hematology | Questions with 100% Verified Answers | Latest
Update 2026/2027
Question: A nurse is caring for a client who has an upper gastrointestinal bleed and a hematocrit of 24%. Prior
to initiating a transfusion of packed red blood cells (RBCs), which of the following actions should the nurse
take? (Select all that apply.)
A. Assess and document the client's vital signs
B. Restart the IV with a 22-gauge needle
C. Verify with another nurse the blood type and Rh of the
packed RBCs
D. Hang a bag of lactated Ringer's IV solution
E. Change IV tubing to a set that has a filter
Answer: A. Assess and document the client's vital signs
C. Verify with another nurse the blood type and Rh of the packed RBCs
E. Change IV tubing to a set that has a filter
The nurse should assess and document the client's vital signs prior to initiating a blood transfusion to obtain a
baseline for comparison. Monitoring the client's vital signs helps the nurse identify adverse reactions to the
packed RBCs and determine whether the client is tolerating the volume of the prescribed blood product. The
nurse should verify the blood type and Rh of the packed RBCs with another RN and compare these data with
the client's information for compatibility. This action decreases the risk of an ABO incompatibility reaction. The
nurse should administer packed RBCs through IV tubing that has a filter to prevent the administration of
aggregates and possible contaminants.
Question: A nurse is providing discharge teaching to a client who had a sickle cell crisis. Which of the following
statements indicates that the client understands the instructions?
A. "I should try to drink at least 2 liters of fluid per day."
B. "I can still fly out to visit my sister in Colorado for a while."
C. "Physical activity is good for me, but I need to avoid
overexertion."
D. "I can still go skiing during the cold winter months."
Answer: C. "Physical activity is good for me, but I need to avoid overexertion."
To help prevent a recurrence of sickle cell crisis, the client should avoid overexertion from especially strenuous
activities.
Question: A nurse is planning care for a client during a sickle cell crisis. Which of the following interventions
should the nurse include in the client's plan of care?
A. Maintain the client's knees and hips in a flexed position
B. Apply cold compresses to painful joints
C. Withhold opioids until the crisis is resolved
D. Encourage increased fluid intake
Answer: D. Encourage increased fluid intake
The nurse should encourage increased fluid intake to promote hydration because dehydration increases the
viscosity of the blood, which can aggravate sickling and client discomfort.
, Question: A nurse is providing discharge teaching for a client who had a bone marrow transplant and has
thrombocytopenia. Which of the following statements indicates that the client understands the precautions he
must take at home?
A. "I'll stick with soft foods for now."
B. "My family will be bringing me fresh flowers today."
C. "I'll use a new disposable razor each day."
D. "I'll blow my nose more often to avoid nosebleeds."
Answer: A. "I'll stick with soft foods for now."
Thrombocytopenia (a low platelet count) is common after a bone marrow transplant. To prevent bleeding until
the client's platelet count improves, the client should avoid hard foods that could cause mouth trauma.
Question: A nurse is preparing an in-service presentation about the basics of hematology. Which of the
following factors provides a stimulus for the production of RBCs?
A. Venous stasis
B. Thrombocytopenia
C. Inflammation
D. Tissue hypoxia
Answer: D. Tissue hypoxia
In response to tissue hypoxia, the kidneys release erythropoietin, which stimulates the production of
erythrocytes (RBCs) in the bone marrow.
Question: A nurse is assessing a client who is receiving a unit of whole blood. Which of the following findings
should the nurse identify as a manifestation of a hemolytic transfusion reaction?
A. Bradycardia
B. Paresthesia
C. Hypertension
D. Low back pain
Answer: D. Low back pain
Low back pain is a manifestation of a hemolytic transfusion reaction. Other manifestations include a headache,
chest pain, tachypnea, tachycardia, and dark urine.
Question: A nurse is assessing the hematologic system of an older adult client. The nurse should report which
of the following findings to the provider as a possible indication of a hematologic disorder?
A. Pallor
B. Jaundice
C. Absence of hair on the legs
D. Poor nailbed capillary refill
Answer: C. Absence of hair on the legs
A progressive loss of hair is common with aging. However, thinning or absence of hair on the extremities
indicates poor arterial circulation to that area. The nurse should look for further indications of arterial
insufficiency and report these findings to the provider.
Question: A client who has thrombocytopenia asks the nurse why platelets are so important. Which of the
following responses should the nurse make?
A. "Platelets help the body fight infection."
B. "Platelets help break down clots in the body."
C. "Platelets plug breaks in blood vessels."
D. "Platelets produce the molecules that carry oxygen."
Answer: C. "Platelets plug breaks in blood vessels."
Platelets help maintain hemostasis and coagulation by plugging disruptions in the integrity of blood vessels.
When an injury occurs to a blood vessel, platelets collect at the edge of the break and adhere to each other to
plug the injured area and limit blood loss.
Update 2026/2027
Question: A nurse is caring for a client who has an upper gastrointestinal bleed and a hematocrit of 24%. Prior
to initiating a transfusion of packed red blood cells (RBCs), which of the following actions should the nurse
take? (Select all that apply.)
A. Assess and document the client's vital signs
B. Restart the IV with a 22-gauge needle
C. Verify with another nurse the blood type and Rh of the
packed RBCs
D. Hang a bag of lactated Ringer's IV solution
E. Change IV tubing to a set that has a filter
Answer: A. Assess and document the client's vital signs
C. Verify with another nurse the blood type and Rh of the packed RBCs
E. Change IV tubing to a set that has a filter
The nurse should assess and document the client's vital signs prior to initiating a blood transfusion to obtain a
baseline for comparison. Monitoring the client's vital signs helps the nurse identify adverse reactions to the
packed RBCs and determine whether the client is tolerating the volume of the prescribed blood product. The
nurse should verify the blood type and Rh of the packed RBCs with another RN and compare these data with
the client's information for compatibility. This action decreases the risk of an ABO incompatibility reaction. The
nurse should administer packed RBCs through IV tubing that has a filter to prevent the administration of
aggregates and possible contaminants.
Question: A nurse is providing discharge teaching to a client who had a sickle cell crisis. Which of the following
statements indicates that the client understands the instructions?
A. "I should try to drink at least 2 liters of fluid per day."
B. "I can still fly out to visit my sister in Colorado for a while."
C. "Physical activity is good for me, but I need to avoid
overexertion."
D. "I can still go skiing during the cold winter months."
Answer: C. "Physical activity is good for me, but I need to avoid overexertion."
To help prevent a recurrence of sickle cell crisis, the client should avoid overexertion from especially strenuous
activities.
Question: A nurse is planning care for a client during a sickle cell crisis. Which of the following interventions
should the nurse include in the client's plan of care?
A. Maintain the client's knees and hips in a flexed position
B. Apply cold compresses to painful joints
C. Withhold opioids until the crisis is resolved
D. Encourage increased fluid intake
Answer: D. Encourage increased fluid intake
The nurse should encourage increased fluid intake to promote hydration because dehydration increases the
viscosity of the blood, which can aggravate sickling and client discomfort.
, Question: A nurse is providing discharge teaching for a client who had a bone marrow transplant and has
thrombocytopenia. Which of the following statements indicates that the client understands the precautions he
must take at home?
A. "I'll stick with soft foods for now."
B. "My family will be bringing me fresh flowers today."
C. "I'll use a new disposable razor each day."
D. "I'll blow my nose more often to avoid nosebleeds."
Answer: A. "I'll stick with soft foods for now."
Thrombocytopenia (a low platelet count) is common after a bone marrow transplant. To prevent bleeding until
the client's platelet count improves, the client should avoid hard foods that could cause mouth trauma.
Question: A nurse is preparing an in-service presentation about the basics of hematology. Which of the
following factors provides a stimulus for the production of RBCs?
A. Venous stasis
B. Thrombocytopenia
C. Inflammation
D. Tissue hypoxia
Answer: D. Tissue hypoxia
In response to tissue hypoxia, the kidneys release erythropoietin, which stimulates the production of
erythrocytes (RBCs) in the bone marrow.
Question: A nurse is assessing a client who is receiving a unit of whole blood. Which of the following findings
should the nurse identify as a manifestation of a hemolytic transfusion reaction?
A. Bradycardia
B. Paresthesia
C. Hypertension
D. Low back pain
Answer: D. Low back pain
Low back pain is a manifestation of a hemolytic transfusion reaction. Other manifestations include a headache,
chest pain, tachypnea, tachycardia, and dark urine.
Question: A nurse is assessing the hematologic system of an older adult client. The nurse should report which
of the following findings to the provider as a possible indication of a hematologic disorder?
A. Pallor
B. Jaundice
C. Absence of hair on the legs
D. Poor nailbed capillary refill
Answer: C. Absence of hair on the legs
A progressive loss of hair is common with aging. However, thinning or absence of hair on the extremities
indicates poor arterial circulation to that area. The nurse should look for further indications of arterial
insufficiency and report these findings to the provider.
Question: A client who has thrombocytopenia asks the nurse why platelets are so important. Which of the
following responses should the nurse make?
A. "Platelets help the body fight infection."
B. "Platelets help break down clots in the body."
C. "Platelets plug breaks in blood vessels."
D. "Platelets produce the molecules that carry oxygen."
Answer: C. "Platelets plug breaks in blood vessels."
Platelets help maintain hemostasis and coagulation by plugging disruptions in the integrity of blood vessels.
When an injury occurs to a blood vessel, platelets collect at the edge of the break and adhere to each other to
plug the injured area and limit blood loss.
