Katzung's Basic and Clinical Pharmacology 16th Edition Test Bank (Chapters 1-66) – 2025 Edition – Instant Download!!

TEST BANK FOR BASIC AND CLINICAL
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PHARMACOLOGY16TH EDITION KATZUNG’S TESTBANK
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/ALL CHS 1-
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66/COMPLETE GUIDE 2024-2025 tr tr

,CH 1. Introduction: The Nature of Drugs & Drug Development & Regulation
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1. A nurse working in radiology administers iodine to a hospital client who
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is having a computed tomography (CT) scan. The nursing attendant
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working on the oncology unit administers chemotherapy to hospital
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clients who have cancer. At the Public Health Department, a nursing
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attendant administers a measles-mumps-r ubella (MMR) vaccine to a 14-
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month-old child as a routine immunization. Which branch of
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pharmacology best describes the actions of all three
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nursing attendants? tr



A) Pharmacoeconomics

B) Pharmacotherapeutics
C) Pharmacodynamics

D) Pharmacokinetics
ACCURATE CHOICE:- tr B
Reasoning :->>>>>> tr




Pharmacology is the study of the biologic effects of chemicals. Nursing tr tr tr tr tr tr tr tr tr tr


attendants are involved with clinical pharmacology or
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pharmacotherapeutics, which is a branch of pharmacology that deals with
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the uses of drugs to treat,prevent, and diagnose disease. The radiology
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nursing attendant is administering a drug to help diagnose a disease. The
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oncology nursing attendant is administering a drug to help treat a disease.
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Pharmacoeconomics includes any costs involved in drug therapy.
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Pharmacodynamics involves how a drug affects the body and tr tr tr tr tr tr tr tr


pharmacokinetics is how the body acts on the body. tr tr tr tr tr tr tr tr




2. When involved in phase III drug evaluation studies,
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whatr esponsibilities would the nursing attendant have?
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A) Working with animals who are given experimental drugs
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B) Choosing appropriate hospital clients to be involved in the drug study
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C) Monitoring and observing hospital clients closely for adverse effects
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D) Conducting research to determine effectiveness of the drug tr tr tr tr tr tr tr

,ACCURATE CHOICE:- tr C

Reasoning:->>>>>>

Phase III studies involve use of a drug in a vast clinical population in
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whichhospital clients are asked to record any symptoms they experience
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while taking the drugs. Nursing attendants may be responsible for helping
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collect and analyzet he information to be shared with the Food and Drug
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Administration (FDA)but would not conduct research independently
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because nursing attendants donot prescribe medications. Use of animals
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in drug testing is done in the preclinical trials. Select hospital clients who
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are involved in phase II studies to participate in studies where the
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participants have the disease the drug is intended to treat. These hospital
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clients are monitored closely for drug action and adverse effects. Phase I
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studies involve healthy human volunteers who are usually paid for their
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participation. Nursing attendants may observe for
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adverse effects and toxicity. tr tr tr




3. A physician has ordered intramuscular (IM) injections of morphine, a
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narcotic, every 4 hours as needed for pain in a motor vehicle accident
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victim. The nursing attendant is aware this drug has a high abuse potential.
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Under what category would morphine be classified?
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A) Schedule I tr




B) Schedule II tr




C) Schedule III tr




D) Schedule IV tr




ACCURATE CHOICE:- tr B
Reasoning:->>>>>>

Narcotics with a high abuse potential are classified as Schedule II drugs
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because of severe dependence liability. Schedule I drugs have high abuse
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potential and no accepted medical use. Schedule III drugs have a lesser
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abuse potential than II and an accepted medical use. Schedule IV drugs
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havel ow abuse potential and limited dependence liability.
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4. What concept is considered when generic drugs are substituted for
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brand name drugs?
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A) Bioavailability

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B) Critical concentration tr




C) Distribution
D) Half-life

ACCURATE CHOICE:-A
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Reasoning:->>>>>>

Bioavailability is the portion of a dose of a drug that reaches the systemic tr tr tr tr tr tr tr tr tr tr tr tr tr


circulation and is available to act on body cells. Binders used in a generic
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drug may not be the same as those used in the brand name drug.
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Therefore, the way the body breaks down and uses the drug may differ,
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which may eliminate a generic drug substitution. Critical concentration is
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the amount ofa drug that is needed to cause a therapeutic effect and
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should not differ between generic and brand name medications.
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Distribution is the phase of pharmacokinetics, which involves the
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movement of a drug to the bodys tissues and is the same in generic and
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brand name drugs. A drugs half-life ist he time it takes for the amount of
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drug to decrease to half the peak level, which should not change when
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substituting a generic medication.
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5. A nursing attendant is assessing the hospital clients home medication use. After
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listening to the hospital client list current medications, the nursing
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attendant askswhat priority question?
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A) Do you take any generic medications?
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B) Are any of these medications orphan drugs?
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C) Are these medications safe to take during pregnancy?
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D) Do you take any over-the-counter medications?
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ACCURATE CHOICE:-tr D

Reasoning:->>>>>>

It is important for the nursing attendant to specifically question use of
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over- the-counter medications because hospital clients may not consider
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them important. The hospital client is unlikely to know the meaning of
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orphan drugs unless they too are primary health care providers. Safety
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during pregnancy, use of a genericmedication, or classification of orphan
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drugs are things the hospital client would be unable to answer but could
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be found in reference books if the nursing attendant wishes to research
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them.
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