AMERICAN BOARD OF INTERNAL MEDICINE · ABIM
GUARANTEED
IBD, Diarrhea &
PASS.
Malabsorption
Review
110 Practice Questions with Rationales
EXAM FOCUS:
Gastroenterology & Nutrition
— Board Review
Edition 1 · August 2026
Prepare · Practice · Pass
Excellence in Internal Medicine Education
EXAM DETAILED HIGH YIELD CONFIDENCE
ABIM — Gastroenterology Page 1
,ABIM — GASTROENTEROLOGY TABLE OF CONTENTS
Table of Contents
1. Instructions for Use 3
2. Practice Questions (Q1-110) 3
ABIM — Gastroenterology Page 2
,ABIM — GASTROENTEROLOGY INSTRUCTIONS & PRACTICE QUESTIONS
How to Use This Guide
Read each stem, choose your answer, then check the rationale directly below it. The correct
option is marked, and each wrong option is explained so you understand why it's wrong — not
just that it is. This guide contains 110 questions covering ABIM board review content in
gastroenterology, IBD, diarrhea, and malabsorption.
IBD, Diarrhea, Malabsorption & Nutrition — Practice Questions
1 A patient with Crohn's disease presents with Cr of 2.0, not dehydrated, with a high
eosinophil count. What is the most likely diagnosis?
A Mesalamine-induced interstitial nephritis
B Crohn's-related renal disease
C Acute tubular necrosis
D Glomerulonephritis
Why A is correct: Mesalamine can cause interstitial nephritis. Renal function should be
monitored when on mesalamine.
B — Crohn's does not directly cause this pattern.
C — ATN is associated with dehydration or ischemia.
D — Glomerulonephritis is not typical.
, 2 The most common side effect of infliximab when used in Crohn's disease is:
A Arthralgias
B Infusion reactions
C Infections
D Malignancy
Why A is correct: Arthralgias are the most common side effect of infliximab in Crohn's
disease.
B — Infusion reactions are less common.
C — Infections are a serious risk but less common.
D — Malignancy is a rare risk.
3 A patient with ulcerative colitis has shallow, continuous lesions on colonoscopy with
rectal involvement. What is the most likely diagnosis?
A Ulcerative colitis
B Crohn's disease
C Ischemic colitis
D Infectious colitis
Why A is correct: Ulcerative colitis is characterized by shallow, continuous lesions starting
in the rectum and extending proximally.
B — Crohn's has skip lesions and transmural inflammation.
C — Ischemic colitis has different findings.
D — Infectious colitis is acute and resolves with treatment.
GUARANTEED
IBD, Diarrhea &
PASS.
Malabsorption
Review
110 Practice Questions with Rationales
EXAM FOCUS:
Gastroenterology & Nutrition
— Board Review
Edition 1 · August 2026
Prepare · Practice · Pass
Excellence in Internal Medicine Education
EXAM DETAILED HIGH YIELD CONFIDENCE
ABIM — Gastroenterology Page 1
,ABIM — GASTROENTEROLOGY TABLE OF CONTENTS
Table of Contents
1. Instructions for Use 3
2. Practice Questions (Q1-110) 3
ABIM — Gastroenterology Page 2
,ABIM — GASTROENTEROLOGY INSTRUCTIONS & PRACTICE QUESTIONS
How to Use This Guide
Read each stem, choose your answer, then check the rationale directly below it. The correct
option is marked, and each wrong option is explained so you understand why it's wrong — not
just that it is. This guide contains 110 questions covering ABIM board review content in
gastroenterology, IBD, diarrhea, and malabsorption.
IBD, Diarrhea, Malabsorption & Nutrition — Practice Questions
1 A patient with Crohn's disease presents with Cr of 2.0, not dehydrated, with a high
eosinophil count. What is the most likely diagnosis?
A Mesalamine-induced interstitial nephritis
B Crohn's-related renal disease
C Acute tubular necrosis
D Glomerulonephritis
Why A is correct: Mesalamine can cause interstitial nephritis. Renal function should be
monitored when on mesalamine.
B — Crohn's does not directly cause this pattern.
C — ATN is associated with dehydration or ischemia.
D — Glomerulonephritis is not typical.
, 2 The most common side effect of infliximab when used in Crohn's disease is:
A Arthralgias
B Infusion reactions
C Infections
D Malignancy
Why A is correct: Arthralgias are the most common side effect of infliximab in Crohn's
disease.
B — Infusion reactions are less common.
C — Infections are a serious risk but less common.
D — Malignancy is a rare risk.
3 A patient with ulcerative colitis has shallow, continuous lesions on colonoscopy with
rectal involvement. What is the most likely diagnosis?
A Ulcerative colitis
B Crohn's disease
C Ischemic colitis
D Infectious colitis
Why A is correct: Ulcerative colitis is characterized by shallow, continuous lesions starting
in the rectum and extending proximally.
B — Crohn's has skip lesions and transmural inflammation.
C — Ischemic colitis has different findings.
D — Infectious colitis is acute and resolves with treatment.
