OpenStax Pharmacology for Nurses |
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231.) A client admitted to the hospital gives the nurse a bottle of clomipramine
(Anafranil). The nurse notes that the medication has not been taken by the client in 2 months.
What behaviors observed in the client would validate noncompliance with this medication?
1. Complaints of hunger
2. Complaints of insomnia
3. A pulse rate less than 60 beats per minute
4. Frequent handwashing with hot, soapy water
4. Frequent handwashing with hot, soapy water
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Rationale:
Clomipramine is commonly used in the treatment of obsessive-compulsive
disorder. Handwashing is a common obsessive-compulsive behavior. Weight gain is a
common side effect of this medication. Tachycardia and sedation are side effects. Insomnia
may occur but is seldom a side effect.
232.) A client in the mental health unit is administered haloperidol (Haldol). The nurse would
check which of the following to determine medication effectiveness?
1. The client's vital signs
2. The client's nutritional intake
3. The physical safety of other unit clients
4. The client's orientation and delusional status
4. The client's orientation and delusional status
Rationale:
Haloperidol is used to treat clients exhibiting psychotic features. Therefore, to determine
medication effectiveness, the nurse would check the client's orientation and delusional
status. Vital signs are routine and not specific to this situation. The physical safety of other
clients is not a direct assessment of this client. Monitoring nutritional intake is not related to
this situation.
233.) Diphenhydramine hydrochloride (Benadryl) is used in the treatment of allergic rhinitis for
a hospitalized client with a chronic psychotic disorder. The client asks the nurse why the
medication is being discontinued before hospital discharge. The nurse responds, knowing
that:
1. Allergic symptoms are short in duration.
2. This medication promotes long-term extrapyramidal symptoms.
3. Addictive properties are enhanced in the presence of psychotropic medications.
4. Poor compliance causes this medication to fail to reach its therapeutic blood level.
3. Addictive properties are enhanced in the presence of psychotropic medications.
Rationale:
The addictive properties of diphenhydramine hydrochloride are enhanced when used with
psychotropic medications. Allergic symptoms may not be short term and will occur if allergens
are present in the environment. Poor compliance may be a problem with psychotic clients but
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is not the subject of the question. Diphenhydramine hydrochloride may be used for
extrapyramidal symptoms and mild medication-induced movement disorders.
234.) A hospitalized client is started on phenelzine sulfate (Nardil) for the treatment
of depression. At lunchtime, a tray is delivered to the client. Which food item on the tray will
the nurse remove?
1. Yogurt
2. Crackers
3. Tossed salad
4. Oatmeal cookies
1. Yogurt
Rationale:
Phenelzine sulfate is a monoamine oxidase inhibitor (MAOI). The client should avoid taking in
foods that are high in tyramine. These foods could trigger a potentially fatal hypertensive
crisis. Foods to avoid include yogurt, aged cheeses, smoked or processed meats, red wines,
and fruits such as avocados, raisins, or figs.
235.) A tricyclic antidepressant is administered to a client daily. The nurse plans to monitor for
the common side effects of the medication and includes which of the following in the plan of
care?
1. Offer hard candy or gum periodically.
2. Offer a nutritious snack between meals.
3. Monitor the blood pressure every 2 hours.
4. Review the white blood cell (WBC) count results daily.
1. Offer hard candy or gum periodically.
Rationale:
Dry mouth is a common side effect of tricyclic antidepressants. Frequent mouth rinsing with
water, sucking on hard candy, and chewing gum will alleviate this common side effect. It is
not necessary to monitor the blood pressure every 2 hours. In addition, it is not necessary to
check the WBC daily. Weight gain is a common side effect and frequent snacks will aggravate
this problem.
236.) A client is being treated for depression with amitriptyline hydrochloride. During the initial
phases of treatment, the most important nursing intervention is:
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1. Prescribing the client a tyramine-free diet
2. Checking the client for anticholinergic effects
3. Monitoring blood levels frequently because there is a narrow range between therapeutic
and toxic blood levels of this medication
4. Getting baseline postural blood pressures before administering the medication and each
time the medication is administered
4. Getting baseline postural blood pressures before administering the medication and each
time the medication is administered
Rationale:
Amitriptyline hydrochloride is a tricyclic antidepressant often used to treat depression. It
causes orthostatic changes and can produce hypotension and tachycardia. This can be
frightening to the client and dangerous because it can result in dizziness and client falls. The
client must be instructed to move slowly from a lying to a sitting to a standing position to
avoid injury if these effects are experienced. The client may also experience sedation, dry
mouth, constipation, blurred vision, and other anticholinergic effects, but these are transient
and will diminish with time.
237.) A client who is on lithium carbonate (Lithobid) will be discharged at the end of the week.
In formulating a discharge teaching plan, the nurse will instruct the client that it is most
important to:
1. Avoid soy sauce, wine, and aged cheese.
2. Have the lithium level checked every week.
3. Take medication only as prescribed because it can become addicting.
4. Check with the psychiatrist before using any over-the-counter (OTC) medications or
prescription medications.
4. Check with the psychiatrist before using any over-the-counter (OTC) medications or
prescription medications.
Rationale:
Lithium is the medication of choice to treat manic-depressive illness. Many OTC medications
interact with lithium, and the client is instructed to avoid OTC medications while taking
lithium. Lithium is not addicting, and, although serum lithium levels need to be monitored, it is
not necessary to check these levels every week. A tyramine-free diet is associated with
monoamine oxidase inhibitors.
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