BSN 315 Varcarolis Psychopharmacology – Questions
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Terms in this set (70)
,Key Concepts ↑ dopamine - schizophrenia
↓ norepinephrine and/or serotonin - depression and
anxiety
↓ GABA - anxiety
Antipsychotic drugs: ↓ dopamine
Antidepressant drugs: ↑ norepinephrine and/or
serotonin
Antianxiety drugs: ↑ GABA or ↑ 5-HT and/or
norepinephrine
ANTIDEPRESSANT: ↑ serotonin
ANTIANXIETY: ↑ GABA
SEDATIVE HYPNOTIC: ↑ histamine
MOOD STABILIZER: ↑↓ norepinephrine
ANTIPSYCHOTIC: ↓ dopamine
ANTICHOLINESTERASE: ↑↓ acetylcholine
Monoamine neurotransmitters - implicated in a variety of neuropsychiatric disorders
(among with acetylcholine)
Biogenic amines:
Catecholamines:
- norepinephrine,
- epinephrine,
- dopamine
Indolamines:
- serotonin
MAO / monoamine oxidase - monoamine transmitters destructive enzyme
,dopamine DA - involved in cognition, complex movements,
motivation, and regulation of emotional responses.
- stimulates body's natural "feel good" reward pathways,
producing pleasant euphoric sensation under certain
conditions.
low: parkinsons, depression
high: schizophrenia, mania
- Fine muscle movement
- Integration of emotions and thoughts
- Decision making
- Stimulates hypothalamus to release hormones (sex,
thyroid, adrenal)
- controls brain's reward and pleasure centers,
- stimulates the heart,
- increases blood flow to vital organs
DRUGS
- drugs that stimulate dopamine activity can induce
psychotic symptoms,
- drugs that block dopamine receptors (e.g.,
haloperidol) have antipsychotic activity
dopamine hypothesis of schizophrenia cocaine (amphetamines) allow more DA to stay active in
synapse for longer time
, norepinephrine NE / α1- and α2- - increases alertness and arousal, and speeds reaction
receptors time.
low: depression, ADHD, low arousal (e.g., sedation), HTN
high: anxiety states, hyperarousal.
- Mood
- Attention and arousal
- Stimulates sympathetic branch of autonomic nervous
system for ''fight or flight'' in response to stress
DRUGS
α1- and α2-receptors blockers
- Prazosin (anti-HTN): treating of nightmares in
posttraumatic stress disorder
- Many FGA (conventional) antipsychotic drugs
SE
- vasodilation
- drop in blood pressure,
- orthostatic hypotension.
- failure to ejaculate (vas deferens)
With Appropriate Solutions
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Match Blocks Charms NEW
Terms in this set (70)
,Key Concepts ↑ dopamine - schizophrenia
↓ norepinephrine and/or serotonin - depression and
anxiety
↓ GABA - anxiety
Antipsychotic drugs: ↓ dopamine
Antidepressant drugs: ↑ norepinephrine and/or
serotonin
Antianxiety drugs: ↑ GABA or ↑ 5-HT and/or
norepinephrine
ANTIDEPRESSANT: ↑ serotonin
ANTIANXIETY: ↑ GABA
SEDATIVE HYPNOTIC: ↑ histamine
MOOD STABILIZER: ↑↓ norepinephrine
ANTIPSYCHOTIC: ↓ dopamine
ANTICHOLINESTERASE: ↑↓ acetylcholine
Monoamine neurotransmitters - implicated in a variety of neuropsychiatric disorders
(among with acetylcholine)
Biogenic amines:
Catecholamines:
- norepinephrine,
- epinephrine,
- dopamine
Indolamines:
- serotonin
MAO / monoamine oxidase - monoamine transmitters destructive enzyme
,dopamine DA - involved in cognition, complex movements,
motivation, and regulation of emotional responses.
- stimulates body's natural "feel good" reward pathways,
producing pleasant euphoric sensation under certain
conditions.
low: parkinsons, depression
high: schizophrenia, mania
- Fine muscle movement
- Integration of emotions and thoughts
- Decision making
- Stimulates hypothalamus to release hormones (sex,
thyroid, adrenal)
- controls brain's reward and pleasure centers,
- stimulates the heart,
- increases blood flow to vital organs
DRUGS
- drugs that stimulate dopamine activity can induce
psychotic symptoms,
- drugs that block dopamine receptors (e.g.,
haloperidol) have antipsychotic activity
dopamine hypothesis of schizophrenia cocaine (amphetamines) allow more DA to stay active in
synapse for longer time
, norepinephrine NE / α1- and α2- - increases alertness and arousal, and speeds reaction
receptors time.
low: depression, ADHD, low arousal (e.g., sedation), HTN
high: anxiety states, hyperarousal.
- Mood
- Attention and arousal
- Stimulates sympathetic branch of autonomic nervous
system for ''fight or flight'' in response to stress
DRUGS
α1- and α2-receptors blockers
- Prazosin (anti-HTN): treating of nightmares in
posttraumatic stress disorder
- Many FGA (conventional) antipsychotic drugs
SE
- vasodilation
- drop in blood pressure,
- orthostatic hypotension.
- failure to ejaculate (vas deferens)
