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AOCNP Essential in Advanced Practice Cancer Treatments Latest recent and frequently tested exam with comprehensive questions and verified accurate solution (detailed & elaborated) GRADED A+.

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AOCNP Essential in Advanced Practice Cancer Treatments Latest recent and frequently tested exam with comprehensive questions and verified accurate solution (detailed & elaborated) GRADED A+.

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AOCNP Essential in Advanced Practice Cancer
Treatments Latest recent and frequently tested
exam with comprehensive questions and verified
accurate solution (detailed & elaborated)
GRADED A+

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,________________is when the disease is expected to be completely removed so that it will not return -
correct ans:Curative Intent



______________is not intended to removal all cancer, but rather to minimize symptoms of cancer. The
goal is to improve quality of life - correct ans:Palliative Treatment



_____________________treatments are administered to slow growth of cancer when cure is not
possible - correct ans:Control



___________is the first treatment that is given for the disease and is sometimes a part of a standard set
of treatments - correct ans:Induction therapy



________________is closely watching the disease without active treatment - correct ans:Active
surveillance



_________________is given after the primary treatment to lower the risk that the disease will come
back - correct ans:Adjuvant therapy



_________________is given to relieve the symptoms caused by a cancer - correct ans:Palliative

- an example of palliative tx is radiation therapy for a bone metastasis that is causing pain



__________is a treatment that is given following induction or initial therapy. It can be used to kill any
additional malignant cells - correct ans:Consolidated therapy

- example is consolidative radiation to a bulky mediastinal node for a patient with non-Hodgkin
Lymphoma who has completed chemotherapy



_______________________is treatment that continues after the initial therapy and is given to help
prevent the malignancy from recurring - correct ans:Maintenance therapy

- example is hormonal therapy such as tamoxifen that is given for breast cancer to reduce the risk of
malignancy from recurring. Maintenance therapy many also be used in metastatic or advanced disease
to help to control the disease, but not cure it

,____________moves basic reaserch finding into the clinic and clinical research finding into everyday
care. In turn, results from clinical and population based studies can guide basic research - correct
ans:Translational research



__________________________ - (descriptive)history studies involving prospective research. Participants
are followed forward in time on the natural course of cancer - correct ans:Observational Research



________________ - (interventional) controlled studies or clinical trials designed to evaluate
prospectively the safety and effectiveness of drugs, devices, or behavioral interventions - correct ans:



The goals of clinical trials is to - correct ans:assess new or investigational drugs, procedures, or device for
safety and efficacy



Types of clinical trials - correct ans:Look below



Evaluates the effectiveness of ways to reduce the risk of developing cancer - correct ans:Prevention Trial



Strives to develop better tests to identify and diagnose a particular disease - correct ans:Diagnostic trial



Assess way to detect health problems earlier - correct ans:Screening trial



Measures ways to improve comfort and quality of life - correct ans:Quality of life trial



Tests treatments, devices, or combinations to treat disease - correct ans:Treatment Trial



Phase 0 - correct ans:Relatively new; earliest steps in human trial



Phase 1 - correct ans:Evaluates safety and dosage



Phase 2 - correct ans:Evaluates of effectiveness

, - evaluate the effectiveness or activity of the drug regimen using the dosage determined to be safe in
Phase 1 trials



Phase 3 - correct ans:Confirmation of effectiveness

- compare the standard of treatment to the new treatment



Phase 4 - correct ans:Involves post marketing studies. Includes trials that are done after the drug is FDA
approved to identify



Participation in clinical trials remain low in all population but especially in: - correct ans:-racial and
ethnic minorities

-older adults

-low income individuals

-people living in rural areas



The NCI ____________________is a tool that clinicians often use to standardize the grading of a
particular adverse event - correct ans:Common Terminology Criteria for Adverse Events (CTCAE)



ANTINEOPLASTICS - correct ans:ANTINEOPLASTICS



Cell cycle nonspecific drugs, which are active throughout cell cycle - correct ans:Alkylating agents -
cyclophosmaide

Anthracycline antibiotics - doxorubicin

Nitrosoureas - carmustine

Miscellaneous - dacarbazine, mitomycin-c



Alkylating agents and how they work - correct ans:-alkylating agents are highly reactive chemical
compounds that attack DNA, generally producing lethal linkage between strands



Alkylating agents include:

Cyclophosphamide and Ifosfamide

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