RICKETTSIA AND SIMILAR ORGANISMS EXAM WITH COMPLETE
SOLUTIONS 100% VERIFIED!!!! ALREADY GRADED A+
Rickettsia - (answer)pleomorphic
gram negative rod
have an outer membrane
inner membrane
(gram positives don't have an outer membrane)
T/F rickettsia are obligate intracellular pathogens (can't grow outside of cells) - (answer)true!
ricketssia don't stay within which components of the cell - (answer)vacuoles or
phagosomes
- they escape out into the cytosol
- out in the cytosol
what do rickettsia do to the actin within the cell - (answer)hijack the actin and use it to propel
themselves
rickettsial life cycle - (answer)1. phagocytosis is induced: infect an endothelial cell
2. bacteria escapes the phagosome: temporarily in membrane bound vacuole
3. filopodium focal lysis
- use actin tails to swim around
- once they replicate inside the cell
- they may lyse the cell
Actin based motility is used by which intracellular pathogens? - (answer)1. listeria monocytogenes
2. shigella flexneri
, RICKETTSIA AND SIMILAR ORGANISMS EXAM WITH COMPLETE
SOLUTIONS 100% VERIFIED!!!! ALREADY GRADED A+
3. rickettsia species
what is responsible for most of the pathogenesis of rickettsia? - (answer)damage to the capillary
endothelium, rickettsia will colonize there and cause damage
- if you damage capillary bed
- leaking into tissues
- loss of vascularity
- microthrombi formed
- loss of perfusion
spotted fever group - (answer)rickettsia rickettsii
rocky mountain spotted fever
what are two more common rickettsia subtypes seen in the US? - (answer)rickettsia rickettsii: Rocky
Mountain Spotted Fever
rickettsia prowazekii- South America, North America, Asia, Africa: cause of epidemic typhus
what are the three rickettsia subtypes that cause typhus? - (answer)rickettsia prowazekii
rickettsia typhi
orientia tsutsugamushi
what does typhus mean - (answer)cloudy
in epidemic typhus you have involvement of CNS, changes in ability to think, clouds your thoughts
Rocky Mountain spotted fever is also known as - (answer)rickettsia rickettsii
tick born illness
occurs throughout US with NE, SE, mid atlantic distribution
SOLUTIONS 100% VERIFIED!!!! ALREADY GRADED A+
Rickettsia - (answer)pleomorphic
gram negative rod
have an outer membrane
inner membrane
(gram positives don't have an outer membrane)
T/F rickettsia are obligate intracellular pathogens (can't grow outside of cells) - (answer)true!
ricketssia don't stay within which components of the cell - (answer)vacuoles or
phagosomes
- they escape out into the cytosol
- out in the cytosol
what do rickettsia do to the actin within the cell - (answer)hijack the actin and use it to propel
themselves
rickettsial life cycle - (answer)1. phagocytosis is induced: infect an endothelial cell
2. bacteria escapes the phagosome: temporarily in membrane bound vacuole
3. filopodium focal lysis
- use actin tails to swim around
- once they replicate inside the cell
- they may lyse the cell
Actin based motility is used by which intracellular pathogens? - (answer)1. listeria monocytogenes
2. shigella flexneri
, RICKETTSIA AND SIMILAR ORGANISMS EXAM WITH COMPLETE
SOLUTIONS 100% VERIFIED!!!! ALREADY GRADED A+
3. rickettsia species
what is responsible for most of the pathogenesis of rickettsia? - (answer)damage to the capillary
endothelium, rickettsia will colonize there and cause damage
- if you damage capillary bed
- leaking into tissues
- loss of vascularity
- microthrombi formed
- loss of perfusion
spotted fever group - (answer)rickettsia rickettsii
rocky mountain spotted fever
what are two more common rickettsia subtypes seen in the US? - (answer)rickettsia rickettsii: Rocky
Mountain Spotted Fever
rickettsia prowazekii- South America, North America, Asia, Africa: cause of epidemic typhus
what are the three rickettsia subtypes that cause typhus? - (answer)rickettsia prowazekii
rickettsia typhi
orientia tsutsugamushi
what does typhus mean - (answer)cloudy
in epidemic typhus you have involvement of CNS, changes in ability to think, clouds your thoughts
Rocky Mountain spotted fever is also known as - (answer)rickettsia rickettsii
tick born illness
occurs throughout US with NE, SE, mid atlantic distribution
