HESI RN INFECTION CONTROL ACCURATE
COMPREHENSIVE PRACTICE EXAM WITH ALL
POSSIBLE APPROVED WELL ELABORATED
PRACTICE QUESTIONS AND 100% CORRECT
VERIFIED ANSWERS WITH DETAILED RATIONALES
PLUS EXPERT ANSWER KEY (100% CORRECT
VERIFIED SOLUTIONS) 2026-2027 CURRENTLY
UPDATED VERSION Q&A GUARANTEED PASS A+
INSTANT DOWNLOAD PDF
1. A nurse is caring for a patient with active
pulmonary tuberculosis. Which type of transmission-
based precaution should be implemented?
A. Contact precautions
B. Droplet precautions
C. Airborne precautions
D. Standard precautions only
,Correct Answer: C. Airborne precautions
Rationale: Mycobacterium tuberculosis is
transmitted via airborne droplet nuclei (≤5
microns). Airborne precautions require a negative-
pressure room, N95 respirator, and limiting patient
transport. Contact and droplet precautions are
incorrect because TB is not spread by direct contact
or large droplets.
2. The nurse prepares to administer a vaccine to a
patient. Which action is most important for infection
control?
A. Wearing gloves
B. Cleaning the injection site with alcohol
C. Performing hand hygiene before and after
D. Using a new needle for each vial entry
Correct Answer: C. Performing hand hygiene
before and after
Rationale: Hand hygiene is the single most
effective measure to prevent healthcare-
associated infections. While a new needle and site
,cleaning are important, hand hygiene is the
primary infection control action. Gloves are not
required for routine IM injections unless contact
with blood is anticipated.
3. A patient with Clostridioides difficile infection has
diarrhea. Which isolation precaution is required?
A. Airborne
B. Droplet
C. Contact
D. Standard
Correct Answer: C. Contact
Rationale: C. difficile is spread by the fecal-oral
route and via contaminated surfaces. Contact
precautions (gown, gloves) are mandatory.
Alcohol-based hand sanitizer is ineffective; soap
and water must be used. Droplet and airborne
precautions do not apply.
4. The nurse observes a colleague removing
personal protective equipment (PPE) after caring for
, a patient on contact precautions. Which action
indicates a breach in protocol?
A. Removing gloves first
B. Removing gown after gloves
C. Removing mask after leaving the room
D. Performing hand hygiene immediately after glove
removal
Correct Answer: B. Removing gown after gloves
Rationale: The correct sequence is to remove
gloves first (most contaminated), then the gown
(second most contaminated), then mask, then eye
protection. Removing the gown after gloves risks
contaminating the hands. Hand hygiene should
follow glove removal.
5. Which patient condition places the patient at
highest risk for a healthcare-associated infection
(HAI)?
A. A 25-year-old with a mild urinary tract infection
B. A 60-year-old with a central venous catheter
C. A 40-year-old with a fractured femur
COMPREHENSIVE PRACTICE EXAM WITH ALL
POSSIBLE APPROVED WELL ELABORATED
PRACTICE QUESTIONS AND 100% CORRECT
VERIFIED ANSWERS WITH DETAILED RATIONALES
PLUS EXPERT ANSWER KEY (100% CORRECT
VERIFIED SOLUTIONS) 2026-2027 CURRENTLY
UPDATED VERSION Q&A GUARANTEED PASS A+
INSTANT DOWNLOAD PDF
1. A nurse is caring for a patient with active
pulmonary tuberculosis. Which type of transmission-
based precaution should be implemented?
A. Contact precautions
B. Droplet precautions
C. Airborne precautions
D. Standard precautions only
,Correct Answer: C. Airborne precautions
Rationale: Mycobacterium tuberculosis is
transmitted via airborne droplet nuclei (≤5
microns). Airborne precautions require a negative-
pressure room, N95 respirator, and limiting patient
transport. Contact and droplet precautions are
incorrect because TB is not spread by direct contact
or large droplets.
2. The nurse prepares to administer a vaccine to a
patient. Which action is most important for infection
control?
A. Wearing gloves
B. Cleaning the injection site with alcohol
C. Performing hand hygiene before and after
D. Using a new needle for each vial entry
Correct Answer: C. Performing hand hygiene
before and after
Rationale: Hand hygiene is the single most
effective measure to prevent healthcare-
associated infections. While a new needle and site
,cleaning are important, hand hygiene is the
primary infection control action. Gloves are not
required for routine IM injections unless contact
with blood is anticipated.
3. A patient with Clostridioides difficile infection has
diarrhea. Which isolation precaution is required?
A. Airborne
B. Droplet
C. Contact
D. Standard
Correct Answer: C. Contact
Rationale: C. difficile is spread by the fecal-oral
route and via contaminated surfaces. Contact
precautions (gown, gloves) are mandatory.
Alcohol-based hand sanitizer is ineffective; soap
and water must be used. Droplet and airborne
precautions do not apply.
4. The nurse observes a colleague removing
personal protective equipment (PPE) after caring for
, a patient on contact precautions. Which action
indicates a breach in protocol?
A. Removing gloves first
B. Removing gown after gloves
C. Removing mask after leaving the room
D. Performing hand hygiene immediately after glove
removal
Correct Answer: B. Removing gown after gloves
Rationale: The correct sequence is to remove
gloves first (most contaminated), then the gown
(second most contaminated), then mask, then eye
protection. Removing the gown after gloves risks
contaminating the hands. Hand hygiene should
follow glove removal.
5. Which patient condition places the patient at
highest risk for a healthcare-associated infection
(HAI)?
A. A 25-year-old with a mild urinary tract infection
B. A 60-year-old with a central venous catheter
C. A 40-year-old with a fractured femur
