HESI RN ONCOLOGY NURSING ACCURATE
COMPREHENSIVE PRACTICE EXAM WITH ALL
POSSIBLE APPROVED WELL ELABORATED
PRACTICE QUESTIONS AND 100% CORRECT
VERIFIED ANSWERS WITH DETAILED RATIONALES
PLUS EXPERT ANSWER KEY (100% CORRECT
VERIFIED SOLUTIONS) 2026-2027 CURRENTLY
UPDATED VERSION Q&A GUARANTEED PASS A+
INSTANT DOWNLOAD PDF
1. The nurse is caring for a client with a platelet
count of 25,000/mm³. Which intervention is the
highest priority?
A. Administering a suppository for constipation
B. Providing a soft-bristled toothbrush for oral
care
C. Encouraging ambulation three times daily
D. Inserting a peripheral intravenous catheter
, B
Thrombocytopenia increases bleeding risk. A
soft-bristled toothbrush reduces gum trauma
and bleeding. Suppositories, IV insertions, and
unnecessary movement can provoke bleeding.
2. A client receiving chemotherapy reports
numbness and tingling in the fingers and toes.
Which chemotherapeutic agent is most likely
responsible?
A. Cyclophosphamide
B. Vincristine
C. Methotrexate
D. Doxorubicin
B
Vincristine is a vinca alkaloid known to cause
peripheral neuropathy, presenting as
paresthesias in the extremities.
3. A client with breast cancer is prescribed
tamoxifen. The nurse should teach the client to
report which symptom immediately?
A. Hot flashes
, B. Leg swelling and pain
C. Vaginal dryness
D. Nausea
B
Tamoxifen increases the risk of
thromboembolic events. Unilateral leg swelling
and pain may indicate deep vein thrombosis,
requiring prompt evaluation.
4. The nurse is caring for a client with tumor lysis
syndrome. Which laboratory value requires
immediate notification of the healthcare
provider?
A. Calcium 9.0 mg/dL
B. Potassium 6.2 mEq/L
C. Phosphate 3.0 mg/dL
D. Sodium 140 mEq/L
B
Tumor lysis syndrome releases intracellular
potassium, causing hyperkalemia. A potassium
of 6.2 mEq/L can lead to life-threatening
dysrhythmias.
, 5. A client receiving radiation therapy to the neck
reports difficulty swallowing and a sore throat.
Which dietary recommendation is most
appropriate?
A. Hot tomato soup with crackers
B. Soft, bland foods and thick liquids
C. Dry toast and citrus fruits
D. Spicy foods to stimulate appetite
B
Radiation to the neck causes mucositis and
esophagitis. Soft, bland foods and thick liquids
minimize mucosal irritation and ease
swallowing.
6. The nurse is teaching a client about preventing
infection during chemotherapy-induced
neutropenia. Which statement by the client
indicates a need for further teaching?
A. “I will avoid fresh flowers in my room.”
B. “I will wash my hands frequently.”
C. “I will eat a salad with raw vegetables daily
for nutrition.”
D. “I will avoid crowds and people who are
COMPREHENSIVE PRACTICE EXAM WITH ALL
POSSIBLE APPROVED WELL ELABORATED
PRACTICE QUESTIONS AND 100% CORRECT
VERIFIED ANSWERS WITH DETAILED RATIONALES
PLUS EXPERT ANSWER KEY (100% CORRECT
VERIFIED SOLUTIONS) 2026-2027 CURRENTLY
UPDATED VERSION Q&A GUARANTEED PASS A+
INSTANT DOWNLOAD PDF
1. The nurse is caring for a client with a platelet
count of 25,000/mm³. Which intervention is the
highest priority?
A. Administering a suppository for constipation
B. Providing a soft-bristled toothbrush for oral
care
C. Encouraging ambulation three times daily
D. Inserting a peripheral intravenous catheter
, B
Thrombocytopenia increases bleeding risk. A
soft-bristled toothbrush reduces gum trauma
and bleeding. Suppositories, IV insertions, and
unnecessary movement can provoke bleeding.
2. A client receiving chemotherapy reports
numbness and tingling in the fingers and toes.
Which chemotherapeutic agent is most likely
responsible?
A. Cyclophosphamide
B. Vincristine
C. Methotrexate
D. Doxorubicin
B
Vincristine is a vinca alkaloid known to cause
peripheral neuropathy, presenting as
paresthesias in the extremities.
3. A client with breast cancer is prescribed
tamoxifen. The nurse should teach the client to
report which symptom immediately?
A. Hot flashes
, B. Leg swelling and pain
C. Vaginal dryness
D. Nausea
B
Tamoxifen increases the risk of
thromboembolic events. Unilateral leg swelling
and pain may indicate deep vein thrombosis,
requiring prompt evaluation.
4. The nurse is caring for a client with tumor lysis
syndrome. Which laboratory value requires
immediate notification of the healthcare
provider?
A. Calcium 9.0 mg/dL
B. Potassium 6.2 mEq/L
C. Phosphate 3.0 mg/dL
D. Sodium 140 mEq/L
B
Tumor lysis syndrome releases intracellular
potassium, causing hyperkalemia. A potassium
of 6.2 mEq/L can lead to life-threatening
dysrhythmias.
, 5. A client receiving radiation therapy to the neck
reports difficulty swallowing and a sore throat.
Which dietary recommendation is most
appropriate?
A. Hot tomato soup with crackers
B. Soft, bland foods and thick liquids
C. Dry toast and citrus fruits
D. Spicy foods to stimulate appetite
B
Radiation to the neck causes mucositis and
esophagitis. Soft, bland foods and thick liquids
minimize mucosal irritation and ease
swallowing.
6. The nurse is teaching a client about preventing
infection during chemotherapy-induced
neutropenia. Which statement by the client
indicates a need for further teaching?
A. “I will avoid fresh flowers in my room.”
B. “I will wash my hands frequently.”
C. “I will eat a salad with raw vegetables daily
for nutrition.”
D. “I will avoid crowds and people who are
