MCB 150 FINAL STUDY GUIDE 2026
COMPLETE SOLUTIONS VERIFIED
PASS
◉ Tubulin.
Answer: globular protein that makes up microtubules
a dimer, composed of two 55 kDa polypeptides (a tubulin and B tubulin)
◉ Microtubule structure.
Answer: 13 linear "protofilaments" surrounding hollow core
assembled head-to-tail, has polarity
◉ Dynamic Instability.
Answer: Alternating cycles of growth and shrinkage
first shown by Mitchison and Kirchner in 1984
◉ Colchicine and Colcemid.
Answer: drugs that block microtubule assembly by binding tubulin
◉ Vincristine and vinblastine.
Answer: drugs that selectively inhibit the microtubule assembly by
binding tubulin in rapidly dividing cells
, ◉ Taxol.
Answer: stabilizes microtubules rather than block formation
◉ MOC.
Answer: Microtubule Organizing Centers, Centrosome, located adjacent
to the nucleus in interphase cells
◉ Centrosome.
Answer: MT Organizing center, in animal cells consists of a pair of
centrioles surrounded by pericentriolar material
◉ Centrioles.
Answer: pair of structures made of microtubules in a "nine triplet"
arrangement with connecting proteins
◉ PCM.
Answer: Pericentriolar Material, amorphous (without shape) collection
of proteins from which the MTs emanate
◉ Gamma Tubulin.
Answer: Source for new MTs, Platform for new MT dimers
◉ Dynein.
Answer: Motor protein that moves towards the minus end
COMPLETE SOLUTIONS VERIFIED
PASS
◉ Tubulin.
Answer: globular protein that makes up microtubules
a dimer, composed of two 55 kDa polypeptides (a tubulin and B tubulin)
◉ Microtubule structure.
Answer: 13 linear "protofilaments" surrounding hollow core
assembled head-to-tail, has polarity
◉ Dynamic Instability.
Answer: Alternating cycles of growth and shrinkage
first shown by Mitchison and Kirchner in 1984
◉ Colchicine and Colcemid.
Answer: drugs that block microtubule assembly by binding tubulin
◉ Vincristine and vinblastine.
Answer: drugs that selectively inhibit the microtubule assembly by
binding tubulin in rapidly dividing cells
, ◉ Taxol.
Answer: stabilizes microtubules rather than block formation
◉ MOC.
Answer: Microtubule Organizing Centers, Centrosome, located adjacent
to the nucleus in interphase cells
◉ Centrosome.
Answer: MT Organizing center, in animal cells consists of a pair of
centrioles surrounded by pericentriolar material
◉ Centrioles.
Answer: pair of structures made of microtubules in a "nine triplet"
arrangement with connecting proteins
◉ PCM.
Answer: Pericentriolar Material, amorphous (without shape) collection
of proteins from which the MTs emanate
◉ Gamma Tubulin.
Answer: Source for new MTs, Platform for new MT dimers
◉ Dynein.
Answer: Motor protein that moves towards the minus end
