WGU D027 PATHOPHARMACOLOGICAL
ADVANCED FOUNDATIONS CERTIFICATION
PREPARATION GUIDE
◉ Autosomal Recessive.
Answer: Both parents are carriers, 25% change of child having, 50%
chance child is a carrier.
◉ Cystic Fibrosis.
Answer: affects pancreas causing secretions in lungs
◉ 21st Trisomy.
Answer: Down Syndrome
◉ Klinefelter Syndrome (XXY).
Answer: male has extra X, female like qualities
◉ Turner Syndrome.
Answer: Missing X in females
◉ Alpha Thalassemia.
,Answer: inherited blood disorder; mild to severe anemia
◉ Beta Thallasemia.
Answer: low hemoglobin; contraindicated medication ferrous sulfate
◉ Prevalence Risk.
Answer: proportion of the population affected at a certain time
◉ Incidence rate.
Answer: number of new cases divided by population
◉ Innate immunity.
Answer: inflammation; increased vascular permeability
◉ B&T lymphocytes.
Answer: immune response
◉ primary malignant tumor.
Answer: lack of organization of cells
◉ glucocorticoids.
, Answer: used in combination with other agent to treat lymphoid
tissue (leukemia). glucocorticoids are directly toxic to lymphoid
tissues.
◉ Selective estrogen receptor modulators (SERM).
Answer: for hormone receptor positive and advanced breast cancer.
(Tamoxifin reduces risk and recurrence risk)
◉ Heart failure.
Answer: impairment of the ventricle to fill with or eject blood; heart
cannot meet metabolic need of the body.
◉ CHF.
Answer: heart cannot keep up with metabolic needs; volume
overload in pulmonary area
◉ Left Ventricular Dysfunction.
Answer: reduced ejection fraction; ventricle having issue ejecting
blood.
◉ normal ejection fraction.
Answer: 55 - 60 % (blood pumped out with each heartbeat)
ADVANCED FOUNDATIONS CERTIFICATION
PREPARATION GUIDE
◉ Autosomal Recessive.
Answer: Both parents are carriers, 25% change of child having, 50%
chance child is a carrier.
◉ Cystic Fibrosis.
Answer: affects pancreas causing secretions in lungs
◉ 21st Trisomy.
Answer: Down Syndrome
◉ Klinefelter Syndrome (XXY).
Answer: male has extra X, female like qualities
◉ Turner Syndrome.
Answer: Missing X in females
◉ Alpha Thalassemia.
,Answer: inherited blood disorder; mild to severe anemia
◉ Beta Thallasemia.
Answer: low hemoglobin; contraindicated medication ferrous sulfate
◉ Prevalence Risk.
Answer: proportion of the population affected at a certain time
◉ Incidence rate.
Answer: number of new cases divided by population
◉ Innate immunity.
Answer: inflammation; increased vascular permeability
◉ B&T lymphocytes.
Answer: immune response
◉ primary malignant tumor.
Answer: lack of organization of cells
◉ glucocorticoids.
, Answer: used in combination with other agent to treat lymphoid
tissue (leukemia). glucocorticoids are directly toxic to lymphoid
tissues.
◉ Selective estrogen receptor modulators (SERM).
Answer: for hormone receptor positive and advanced breast cancer.
(Tamoxifin reduces risk and recurrence risk)
◉ Heart failure.
Answer: impairment of the ventricle to fill with or eject blood; heart
cannot meet metabolic need of the body.
◉ CHF.
Answer: heart cannot keep up with metabolic needs; volume
overload in pulmonary area
◉ Left Ventricular Dysfunction.
Answer: reduced ejection fraction; ventricle having issue ejecting
blood.
◉ normal ejection fraction.
Answer: 55 - 60 % (blood pumped out with each heartbeat)
