in Nursing 2026 | EBP
Study Guide, PICO,
Research Methods,
Practice Questions &
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Rationales
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, Define: Evidence-based practice Systematic approach to rational decision making that facilitates achievement of best
practices
Six steps to EBP 1. Ask a clinical question
2. Collect the most relevant and best evidence
3. Critically appraise the evidence you gather
4. Integrate all evidence with one's clinical expertise and patient preferences and
values in making a practice decision or change
5. Evaluate
6. Share outcomes of EBP changes with others
Ask a clinical question • A problem or area of interest that could be performed more efficiently, consumes
healthcare dollars, or does not make sense
• A knowledge focused trigger
• Clinical trends
• Utilization of PICOT format to state your clinical question
Why should I use PICOT format to state my clinical • The questions you ask will eventually lead you to the evidence for an answer
question? • You want to be able to read the BEST four-to-six articles that specifically address
your practice question
• The more focused a question you ask, the easier it becomes to search for
evidence in the scientific literature
PICOT question P = Patient population of interest
I = Intervention of interest
C = Comparison of interest
O = Outcome
T = Time
Collect the best evidence- what kind and includes • Search for evidence!
• Evidence includes but is not limited to: agency policy and procedure manuals,
quality improvement data, existing clinical practice guidelines, agency experts, staff
educators, risk managers, infection control nurses, and peer reviewed articles
(specifically within the most recent 5 years from the present date)
Critically appraise the evidence you gather • The most difficult step in the EBP process
• Involves evaluation, determining if information is valuable and can be easily
applied, and if there is enough evidence for making a nursing practice change
• Thorough review of elements included in evidence-based articles
Integrate the evidence • How will you incorporate the evidence into practice?
• Integrate evidence with use of teaching tools, clinical practice guidelines, policies
and procedures, and new assessment documentation tools
• Consider staff support and available resources
• Conduct a pilot study and attempt to answer your PICOT question
Evaluate and share outcomes • Did it work? Is it effective?
• Communicate the results to various groups of nurses or other care providers
(facility nursing practice council or research committee)
PICO four-step process P - population of interest
I - intervention
C - comparison
O - outcome
Utilization of the research process • Identification of a researchable problem
• Review of the literature
• Formulation of the research question or hypothesis
• Design of the study
• Implementation of the study
• Drawing conclusions based on findings
• Discussion of clinical implications
• Dissemination of findings