HESI PN PHARMACOLOGY ACCURATE PRACTICE
EXAM WITH ALL POSSIBLE APPROVED WELL
ELABORATED PRACTICE QUESTIONS AND 100%
CORRECT VERIFIED ANSWERS WITH DETAILED
RATIONALES PLUS EXPERT ANSWER KEY (100%
CORRECT VERIFIED SOLUTIONS) 2026-2027
CURRENTLY UPDATED VERSION Q&A
GUARANTEED PASS A+ INSTANT DOWNLOAD PDF
1. A client with heart failure is prescribed digoxin.
Which finding indicates a therapeutic response to
the medication?
A. Increased heart rate
B. Decreased peripheral edema
C. Elevated blood pressure
D. Increased jugular venous distention
Correct Answer: B
,Rationale: Digoxin increases the force of myocardial
contraction and slows the heart rate. A therapeutic
response is evidenced by improved cardiac output,
which leads to decreased peripheral edema,
reduced shortness of breath, and increased urine
output. Tachycardia, hypertension, and increased
jugular venous distention are signs of worsening
heart failure or digoxin toxicity.
2. A client is prescribed warfarin. Which laboratory
value is most important to monitor?
A. Serum creatinine
B. International Normalized Ratio (INR)
C. Platelet count
D. Blood urea nitrogen (BUN)
Correct Answer: B
Rationale: Warfarin is an anticoagulant that
prolongs clotting time. The INR is the primary
laboratory value used to monitor warfarin therapy
and ensure the dose is therapeutic (typically 2-3 for
most indications) while minimizing bleeding risk.
Creatinine, BUN, and platelet count are not specific
to warfarin monitoring.
,3. A client is prescribed furosemide. Which
electrolyte imbalance is a common adverse effect of
this medication?
A. Hyperkalemia
B. Hyponatremia
C. Hypokalemia
D. Hypercalcemia
Correct Answer: C
Rationale: Furosemide is a loop diuretic that inhibits
sodium and chloride reabsorption in the ascending
loop of Henle. It causes increased excretion of
potassium, leading to hypokalemia. Hyperkalemia,
hypercalcemia, and hyponatremia are not typical
adverse effects of furosemide; in fact, furosemide
can be used to treat hyperkalemia and
hypercalcemia.
4. A client is prescribed metformin for type 2
diabetes. Which adverse effect should the nurse
educate the client about?
A. Hypoglycemia
B. Weight gain
C. Lactic acidosis
, D. Bradycardia
Correct Answer: C
Rationale: Metformin carries a risk of lactic acidosis,
a rare but serious adverse effect. It is more likely in
clients with renal impairment, hepatic disease, or
conditions that cause hypoxia. Metformin does not
typically cause hypoglycemia when used alone, and
it is associated with weight neutrality or weight loss,
not weight gain. Bradycardia is not associated with
metformin.
5. A client prescribed enoxaparin asks the nurse,
"Why am I getting this shot in my stomach?" Which
response is most appropriate?
A. "The medication is absorbed fastest in the
abdomen."
B. "Subcutaneous injection in the abdomen provides
consistent absorption."
C. "This is the only site that prevents bleeding
complications."
D. "The injection must be given intramuscularly in
the abdomen."
Correct Answer: B
EXAM WITH ALL POSSIBLE APPROVED WELL
ELABORATED PRACTICE QUESTIONS AND 100%
CORRECT VERIFIED ANSWERS WITH DETAILED
RATIONALES PLUS EXPERT ANSWER KEY (100%
CORRECT VERIFIED SOLUTIONS) 2026-2027
CURRENTLY UPDATED VERSION Q&A
GUARANTEED PASS A+ INSTANT DOWNLOAD PDF
1. A client with heart failure is prescribed digoxin.
Which finding indicates a therapeutic response to
the medication?
A. Increased heart rate
B. Decreased peripheral edema
C. Elevated blood pressure
D. Increased jugular venous distention
Correct Answer: B
,Rationale: Digoxin increases the force of myocardial
contraction and slows the heart rate. A therapeutic
response is evidenced by improved cardiac output,
which leads to decreased peripheral edema,
reduced shortness of breath, and increased urine
output. Tachycardia, hypertension, and increased
jugular venous distention are signs of worsening
heart failure or digoxin toxicity.
2. A client is prescribed warfarin. Which laboratory
value is most important to monitor?
A. Serum creatinine
B. International Normalized Ratio (INR)
C. Platelet count
D. Blood urea nitrogen (BUN)
Correct Answer: B
Rationale: Warfarin is an anticoagulant that
prolongs clotting time. The INR is the primary
laboratory value used to monitor warfarin therapy
and ensure the dose is therapeutic (typically 2-3 for
most indications) while minimizing bleeding risk.
Creatinine, BUN, and platelet count are not specific
to warfarin monitoring.
,3. A client is prescribed furosemide. Which
electrolyte imbalance is a common adverse effect of
this medication?
A. Hyperkalemia
B. Hyponatremia
C. Hypokalemia
D. Hypercalcemia
Correct Answer: C
Rationale: Furosemide is a loop diuretic that inhibits
sodium and chloride reabsorption in the ascending
loop of Henle. It causes increased excretion of
potassium, leading to hypokalemia. Hyperkalemia,
hypercalcemia, and hyponatremia are not typical
adverse effects of furosemide; in fact, furosemide
can be used to treat hyperkalemia and
hypercalcemia.
4. A client is prescribed metformin for type 2
diabetes. Which adverse effect should the nurse
educate the client about?
A. Hypoglycemia
B. Weight gain
C. Lactic acidosis
, D. Bradycardia
Correct Answer: C
Rationale: Metformin carries a risk of lactic acidosis,
a rare but serious adverse effect. It is more likely in
clients with renal impairment, hepatic disease, or
conditions that cause hypoxia. Metformin does not
typically cause hypoglycemia when used alone, and
it is associated with weight neutrality or weight loss,
not weight gain. Bradycardia is not associated with
metformin.
5. A client prescribed enoxaparin asks the nurse,
"Why am I getting this shot in my stomach?" Which
response is most appropriate?
A. "The medication is absorbed fastest in the
abdomen."
B. "Subcutaneous injection in the abdomen provides
consistent absorption."
C. "This is the only site that prevents bleeding
complications."
D. "The injection must be given intramuscularly in
the abdomen."
Correct Answer: B
