NURS 615 EXAM 1 UPDATED ACTUAL
QUESTIONS AND VERIFIED ANSWERS
●● What is a Black Box Warning:
Answer: is considered a contraindication to administer that drug.
●● What is the drugs half-life?
Answer: Half-life specifically means the amount of time it takes for an
administered drug to be halfway cleared from the system.
●● Peak of action:
Answer: the time between drug administration and maximum
concentration of drug in the blood stream. Best therapeutic effect.
●● Duration of action:
Answer: the time between onset of action and metabolism of drug below
the minimum needed for an effect. The length of time you have the drug
in your system.
●● According to the WHO what is the first step in the prescribing
process?
Answer: The first step is to define the patient's problem
,●● The second step is to
Answer: specify the therapeutic objective
●● The third step is to
Answer: choose which drug or treatment is needed.
●● Step 4 of the WHO approach:
Answer: Start the treatment
●● Step 5 of the WHO approach:
Answer: Educate the patient
●● Step 6 of the WHO approach:
Answer: Monitor the treatment
●● Phase 1 of drug development:
Answer: The drug is tested on healthy volunteers
●● Phase 2 of drug development:
Answer: trials with people who have the disease for which the drug is
thought to be effective
, ●● Phase 3 of drug development:
Answer: Large numbers of patients in medical research centers receive
the drug in phase 3. This larger sampling provides information about
infrequent or rare adverse effects. The FFA will approve a new drug
application if phase 3 studies are satisfactory.
●● Phase 4 of drug development:
Answer: This phase is voluntary and involves postmarket surveillance of
the drug's therapeutic effects at the completion of phase 3. The
pharmaceutical company receives reports from doctors and other health
care professionals about the therapeutic results and adverse effects of the
drug. Some medications, for example, have been found to be toxic and
have been removed from the market after their initial release.
●● Explain first pass metabolism
Answer: much of the drug is lost in the absorption process. The liver
metabolizes many drugs, thus reduces the bioavailabilty of the drug.
●● What is the fasted route of absorption:
Answer: The fastest route of absorption is inhalation, and not as
mistakenly considered the IV administration.
●● Why does the GI tract take longer to absorb?
Answer: The GI tract is lined with epithelial cells; drugs must permeate
through these cells in order to be absorbed into the circulatory system.
QUESTIONS AND VERIFIED ANSWERS
●● What is a Black Box Warning:
Answer: is considered a contraindication to administer that drug.
●● What is the drugs half-life?
Answer: Half-life specifically means the amount of time it takes for an
administered drug to be halfway cleared from the system.
●● Peak of action:
Answer: the time between drug administration and maximum
concentration of drug in the blood stream. Best therapeutic effect.
●● Duration of action:
Answer: the time between onset of action and metabolism of drug below
the minimum needed for an effect. The length of time you have the drug
in your system.
●● According to the WHO what is the first step in the prescribing
process?
Answer: The first step is to define the patient's problem
,●● The second step is to
Answer: specify the therapeutic objective
●● The third step is to
Answer: choose which drug or treatment is needed.
●● Step 4 of the WHO approach:
Answer: Start the treatment
●● Step 5 of the WHO approach:
Answer: Educate the patient
●● Step 6 of the WHO approach:
Answer: Monitor the treatment
●● Phase 1 of drug development:
Answer: The drug is tested on healthy volunteers
●● Phase 2 of drug development:
Answer: trials with people who have the disease for which the drug is
thought to be effective
, ●● Phase 3 of drug development:
Answer: Large numbers of patients in medical research centers receive
the drug in phase 3. This larger sampling provides information about
infrequent or rare adverse effects. The FFA will approve a new drug
application if phase 3 studies are satisfactory.
●● Phase 4 of drug development:
Answer: This phase is voluntary and involves postmarket surveillance of
the drug's therapeutic effects at the completion of phase 3. The
pharmaceutical company receives reports from doctors and other health
care professionals about the therapeutic results and adverse effects of the
drug. Some medications, for example, have been found to be toxic and
have been removed from the market after their initial release.
●● Explain first pass metabolism
Answer: much of the drug is lost in the absorption process. The liver
metabolizes many drugs, thus reduces the bioavailabilty of the drug.
●● What is the fasted route of absorption:
Answer: The fastest route of absorption is inhalation, and not as
mistakenly considered the IV administration.
●● Why does the GI tract take longer to absorb?
Answer: The GI tract is lined with epithelial cells; drugs must permeate
through these cells in order to be absorbed into the circulatory system.
