NURS 546 EXAM 2 PRACTICE EVALUATION
2026 QUESTION BANK FULL SOLUTION SET
◉ aripiprazole (Abilify)
cariprazine (Vraylar)
lurasidone (Latuda)
quetiapine (Seroquel)
asenapine (Saphris)
risperidone (Risperdol)
olanzapine (Zyprexa)
ziprazadone (Geodon)
ACTION
-DA, NE, and 5-HT receptor antagonists
INDICATION
-acute bipolar depression
-acute manic or mixed episodes
-bipolar maintenance/adjunct
ADVERSE EFFECTS
-weight gain
-sedation
-GI effects
,PEARLS:
-Indications vary with each medication. Check for monotherapy vs.
adjunct indication.
-Monitor for extrapyramidal effects.
-XR form may improve adherence.
-Monthly injection may improve adherence.
-Select SGAs first to decrease risk of side effects and long-term
adverse effects..
Answer: Second generation antipsychotics for BD
◉ INDICATION
-Seizures
-Pain associated with true tigeminal neuralgia
-Acute mania/mixed mania
ACTION
-glutamate voltage gated sodium and calcium channel blocker (Glu-
CB)
STARTING DOSE
-200 mg BID (tablet), or 100mg QID (suspension)
,ADVERSE EFFECTS
-GI effects
-sedation
-hyponatremia
-neutopenia
-rash (Stevens-Johnson Syndrome)
TESTS
-Before starting get blood count, liver, kidney, and thyroid function
tests.
-During treatment get blood count every 2-4 weeks for 2 months,
then every 3-6 months. And liver, kidney, and tyroid function tests
every 6-12 months
PEARLS:
-Monitor plasma levels.
-Consider genotyping clients with Asian ancestry; the HLA-B 1502
allele increases risk of Steven-Johnson Syndrome.
-Drug interactions: CYP450 3A4 inhibitors, such as nefazodone,
fluvoxamine, and fluoxetine, can increase plasma levels of
carbamazepine..
Answer: carbemazepine (Tegretol)
, ◉ INDICATION
-Depression
Mechanism of Action
-SSRI (selective serotonin reuptake inhibitor); Boosts
neurotransmitter serotonin.
TESTS
-None for healthy individuals
Starting Dose
-20mg/day
Adverse Effects
-Diarrhea, constipation, nausea, sexual dysfuction, activation,
insomnia, agitation, tremors, headache, dizziness, sweating,
bruising, SIADH.
Rare: bleeding, hyponatremia.
PEARLS
-mild antihistamine properties that may contribute to sedation and
fatigue.
Answer: Citalopram (Celexa)
2026 QUESTION BANK FULL SOLUTION SET
◉ aripiprazole (Abilify)
cariprazine (Vraylar)
lurasidone (Latuda)
quetiapine (Seroquel)
asenapine (Saphris)
risperidone (Risperdol)
olanzapine (Zyprexa)
ziprazadone (Geodon)
ACTION
-DA, NE, and 5-HT receptor antagonists
INDICATION
-acute bipolar depression
-acute manic or mixed episodes
-bipolar maintenance/adjunct
ADVERSE EFFECTS
-weight gain
-sedation
-GI effects
,PEARLS:
-Indications vary with each medication. Check for monotherapy vs.
adjunct indication.
-Monitor for extrapyramidal effects.
-XR form may improve adherence.
-Monthly injection may improve adherence.
-Select SGAs first to decrease risk of side effects and long-term
adverse effects..
Answer: Second generation antipsychotics for BD
◉ INDICATION
-Seizures
-Pain associated with true tigeminal neuralgia
-Acute mania/mixed mania
ACTION
-glutamate voltage gated sodium and calcium channel blocker (Glu-
CB)
STARTING DOSE
-200 mg BID (tablet), or 100mg QID (suspension)
,ADVERSE EFFECTS
-GI effects
-sedation
-hyponatremia
-neutopenia
-rash (Stevens-Johnson Syndrome)
TESTS
-Before starting get blood count, liver, kidney, and thyroid function
tests.
-During treatment get blood count every 2-4 weeks for 2 months,
then every 3-6 months. And liver, kidney, and tyroid function tests
every 6-12 months
PEARLS:
-Monitor plasma levels.
-Consider genotyping clients with Asian ancestry; the HLA-B 1502
allele increases risk of Steven-Johnson Syndrome.
-Drug interactions: CYP450 3A4 inhibitors, such as nefazodone,
fluvoxamine, and fluoxetine, can increase plasma levels of
carbamazepine..
Answer: carbemazepine (Tegretol)
, ◉ INDICATION
-Depression
Mechanism of Action
-SSRI (selective serotonin reuptake inhibitor); Boosts
neurotransmitter serotonin.
TESTS
-None for healthy individuals
Starting Dose
-20mg/day
Adverse Effects
-Diarrhea, constipation, nausea, sexual dysfuction, activation,
insomnia, agitation, tremors, headache, dizziness, sweating,
bruising, SIADH.
Rare: bleeding, hyponatremia.
PEARLS
-mild antihistamine properties that may contribute to sedation and
fatigue.
Answer: Citalopram (Celexa)
