NURS 6630 PSYCHOPHARMACOLOGY
MIDTERM 2026 ANTIDEPRESSANTS
ANTIPSYCHOTICS AND MOOD STABILIZERS
CORE CONCEPTS PACKAGE
◉ MAOIs are especially effective in.
Answer: Atypical depression (mood responds to positive events and
symptoms include increased appetite, weight gain, sleepiness, and
fatigue)
◉ Non-selective MAOIs inhibit enzymes.
Answer: MAO-A and MAO-B
◉ Selective MAOIs only inhibit the enzyme:.
Answer: MAO-B
◉ Three non-selective MAOIs:.
Answer: isocarboxazid, phenelzine, tranylcypromine
◉ Non-selective MAOIs increase the levels of these
neurotransmitters:.
,Answer: Serotonin, Norepinephrine, Dopamine
◉ These three non-selective MAOIs bind irreversibly to MAO
enzymes to permanently block their function:.
Answer: isocarboxazid, phenelzine, tranylcypromine
◉ Two selective MAOIs:.
Answer: selegeline, rasagiline
◉ Selective MAOIs increase the level of this neurotransmitter:.
Answer: Dopamine
◉ These selective MAOIs are more commonly prescribed to treat
Parkinson's Disease (a neurodegenerative disorder that effects the
dopaminergic neurons in the substantia nigra region of the brain):.
Answer: selegeline, rasagiline
◉ Adverse effects of MAOIs include:.
Answer: Serotonin syndrome and hypertensive crisis
◉ Before starting another antidepressant MAOIs should be stopped
for at least:.
, Answer: Two weeks (to allow for the body to replace MAO enzymes
so that serotonin syndrome does not occur)
◉ Five main symptoms of hypertensive crisis:.
Answer: hyperthermia, hypertension, tachycardia, arrhythmias,
agitation
◉ Hypertensive crisis commonly occurs when people taking MAOIs
consume foods or drinks high in:.
Answer: tyramine (cheese, wine, beer, cured/smoked meats)
◉ Foods and drinks rich in tyramine:.
Answer: cheese, wine, beer, cured/smoked meats
◉ When uninhibited, these two enzymes are responsible for
breaking down tyramine:.
Answer: MAO-A and MAO-B
◉ When tyramine is not broken down, it increases the release of this
neurotransmitter, which causes hypertensive crisis:.
Answer: Norepinephrine
MIDTERM 2026 ANTIDEPRESSANTS
ANTIPSYCHOTICS AND MOOD STABILIZERS
CORE CONCEPTS PACKAGE
◉ MAOIs are especially effective in.
Answer: Atypical depression (mood responds to positive events and
symptoms include increased appetite, weight gain, sleepiness, and
fatigue)
◉ Non-selective MAOIs inhibit enzymes.
Answer: MAO-A and MAO-B
◉ Selective MAOIs only inhibit the enzyme:.
Answer: MAO-B
◉ Three non-selective MAOIs:.
Answer: isocarboxazid, phenelzine, tranylcypromine
◉ Non-selective MAOIs increase the levels of these
neurotransmitters:.
,Answer: Serotonin, Norepinephrine, Dopamine
◉ These three non-selective MAOIs bind irreversibly to MAO
enzymes to permanently block their function:.
Answer: isocarboxazid, phenelzine, tranylcypromine
◉ Two selective MAOIs:.
Answer: selegeline, rasagiline
◉ Selective MAOIs increase the level of this neurotransmitter:.
Answer: Dopamine
◉ These selective MAOIs are more commonly prescribed to treat
Parkinson's Disease (a neurodegenerative disorder that effects the
dopaminergic neurons in the substantia nigra region of the brain):.
Answer: selegeline, rasagiline
◉ Adverse effects of MAOIs include:.
Answer: Serotonin syndrome and hypertensive crisis
◉ Before starting another antidepressant MAOIs should be stopped
for at least:.
, Answer: Two weeks (to allow for the body to replace MAO enzymes
so that serotonin syndrome does not occur)
◉ Five main symptoms of hypertensive crisis:.
Answer: hyperthermia, hypertension, tachycardia, arrhythmias,
agitation
◉ Hypertensive crisis commonly occurs when people taking MAOIs
consume foods or drinks high in:.
Answer: tyramine (cheese, wine, beer, cured/smoked meats)
◉ Foods and drinks rich in tyramine:.
Answer: cheese, wine, beer, cured/smoked meats
◉ When uninhibited, these two enzymes are responsible for
breaking down tyramine:.
Answer: MAO-A and MAO-B
◉ When tyramine is not broken down, it increases the release of this
neurotransmitter, which causes hypertensive crisis:.
Answer: Norepinephrine
