NUR 635 ADVANCED PHARMACOLOGY
MIDTERM CERTIFICATION EVALUATION
TEST PAPER 2026 COMPREHENSIVE
QUESTIONS AND SOLUTIONS WITH
RATIONALES GRADED A+
⩥ Angina: bc pts dev tolerance to long-acting nitroglycerine w/i 1 day.
How to prevent?
Answer: Pts must have 8hrs with no nitroglycerine every days. Hint: At
night, remove nitro patch bc no risk of exertional angina
⩥ Underlying cause of angina.
Answer: coronary disease, athlerosclerosis
⩥ Why do we give aspirin in pts w/atherosclerosis?.
Answer: Aspirin is an antiplatelet.. Prevents the existing plaques from
getting bigger. Prevents plaque rupture. Cardio protective, prevents
stroke, MI, CVA
⩥ What is prescribed for angina pts w/DM?.
Answer: ACE inhibitors to protect the kidneys and nerves
,⩥ SE of high doses of aspirin?.
Answer: Tinnitus: ringing ears
⩥ Pt education regarding Plavix(clopidogrel bisulfate)?.
Answer: Anti-platelet med. S/sx bleeding: blood in stool or vomit,
excessive bruising, abd pain uterine bld, back pain, petichae. Interactions
with EVERYTHING: OTC, herbals, supplements
⩥ Pts on coumadin? What are we watching for?.
Answer: INR to check therapeutic levels. Half life is long. Check 12hrs
after taking.
⩥ What can be caused if pt started on heparin?.
Answer: day4, ordering blood work to check platelet count to observe
for THROMBOCYTOPENIA
⩥ coumadin and childbearing aged females.
Answer: Interactions with oral contraceptives- must have a back up
method during time you're taking coumadin
⩥ Pregnancy considerations and coumadin.
Answer: Need to monitor anti-Xa levels
, ⩥ biggest food group interaction with coumadin.
Answer: Grapefruit, green leafy veggies. Why? high in vitamin K which
counteracts warfarin
⩥ Short duration: rapid acting insulin indication, MOA, usage.
Answer: Given w/meals
Provide bs control between meals at night
Can use in conjunction w/intermediate or long-acting agent
lispro, aspart, gluulocene
⩥ Short duration: short acting insulin indication, MOA, usage.
Answer: Before meals to control postprandial hyperglycemia
Infused SQ via pump
humulin/regular
⩥ intermediate(humalin/novalin) duration insulin indication, MOA,
usage.
Answer: BS control between meals and during the night
Only one suitable for mixing w/short actings
basal coverage
⩥ Long duration: Insulin glargine U100.
MIDTERM CERTIFICATION EVALUATION
TEST PAPER 2026 COMPREHENSIVE
QUESTIONS AND SOLUTIONS WITH
RATIONALES GRADED A+
⩥ Angina: bc pts dev tolerance to long-acting nitroglycerine w/i 1 day.
How to prevent?
Answer: Pts must have 8hrs with no nitroglycerine every days. Hint: At
night, remove nitro patch bc no risk of exertional angina
⩥ Underlying cause of angina.
Answer: coronary disease, athlerosclerosis
⩥ Why do we give aspirin in pts w/atherosclerosis?.
Answer: Aspirin is an antiplatelet.. Prevents the existing plaques from
getting bigger. Prevents plaque rupture. Cardio protective, prevents
stroke, MI, CVA
⩥ What is prescribed for angina pts w/DM?.
Answer: ACE inhibitors to protect the kidneys and nerves
,⩥ SE of high doses of aspirin?.
Answer: Tinnitus: ringing ears
⩥ Pt education regarding Plavix(clopidogrel bisulfate)?.
Answer: Anti-platelet med. S/sx bleeding: blood in stool or vomit,
excessive bruising, abd pain uterine bld, back pain, petichae. Interactions
with EVERYTHING: OTC, herbals, supplements
⩥ Pts on coumadin? What are we watching for?.
Answer: INR to check therapeutic levels. Half life is long. Check 12hrs
after taking.
⩥ What can be caused if pt started on heparin?.
Answer: day4, ordering blood work to check platelet count to observe
for THROMBOCYTOPENIA
⩥ coumadin and childbearing aged females.
Answer: Interactions with oral contraceptives- must have a back up
method during time you're taking coumadin
⩥ Pregnancy considerations and coumadin.
Answer: Need to monitor anti-Xa levels
, ⩥ biggest food group interaction with coumadin.
Answer: Grapefruit, green leafy veggies. Why? high in vitamin K which
counteracts warfarin
⩥ Short duration: rapid acting insulin indication, MOA, usage.
Answer: Given w/meals
Provide bs control between meals at night
Can use in conjunction w/intermediate or long-acting agent
lispro, aspart, gluulocene
⩥ Short duration: short acting insulin indication, MOA, usage.
Answer: Before meals to control postprandial hyperglycemia
Infused SQ via pump
humulin/regular
⩥ intermediate(humalin/novalin) duration insulin indication, MOA,
usage.
Answer: BS control between meals and during the night
Only one suitable for mixing w/short actings
basal coverage
⩥ Long duration: Insulin glargine U100.
