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NUR 635 ADVANCED PHARMACOLOGY
MIDTERM ACTUAL EXAMINATION TEST
2026 COMPLETE QUESTIONS AND
CORRECT ANSWERS WITH RATIONALES
GRADED A+

⩥ The term NOT associated with the pharmacokinetics of a drug is.
Answer: Pharmacodynamics


Rationale: Pharmacokinetics can be simply described as the study of
'what the body does to the drugs' and includes: the rate and extend to
which drugs are absorbed and distributed to body tissue; the rate and
pathways by which drugs are eliminated from the body by metabolism
and excretion; and the relationship between time and plasma drug
concentration. It includes the processes of absorption, distribution,
metabolism, and excretion. Pharmacodynamics is the effect that a drug
has on the body. Terms associated with pharmacodynamics include
receptors (i.e. affinity), drug potency (i.e. amount of drug required to
produce a therapeutic response), and drug response cure (i.e. effective
dose, toxic dose, therapeutic index).


⩥ The elimination phase of pharmacokinetics is the time it takes for the
plasma concentration of a drug to decrease by.
Answer: 50%

, Rationale: The elimination phase or elimination half-life is the time
required for a drug to reach half (50%) of its state in the serum.


⩥ The pharmacokinetics of a drug may be affected by.
Answer: Compliance by the patient.


Rationale: Factors that affect the pharmacokinetics (what the body does
to the drug) of a drug include: compliance by the patient; dosing and
medication error; absorption; tissue and body fluid; mass and volume;
drug interaction; elimination and drug metabolism. Pharmacokinetics
will be variable if the drug does not reach the body or doesn't stay in the
body long enough. Pharmacodynamics (what the drug does to the body)
is affected by drug receptors, genetic factors, drug interaction, and
tolerance.


⩥ In the pharmacokinetics of a drug, the rate of metabolism:.
Answer: varies widely among patients.


Rationale: Metabolism is the process by which drugs are chemically
changed from a lipid-soluble from suitable for absorption and
distribution to a more water-soluble form that is suitable for excretion.
The rate of drug metabolism varies widely among patients, influenced
by genetic and environmental factors. This is the major reason for
differences in the plasma concentration of some drugs after a standard
dose, leading to wide variation in drug response.

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