1|Page
FHEA Exam Newest 2026/2027 Verified Questions And Anwers
||Just Out!!!
Which pharmacogenomic marker helps to predict weight gain,
particularly related to the use of second generation
antipsychotics and other complex serotonergics?
A. SLC6A4
B. DRD2
C. 5HT2C
D. COMT - ANSWER-C. 5HT2C
All of the following medications may be therapeutic for Panic
Disorder, except:
A. serotonergics (SSRIs)
B. benzodiazepines (BZDs)
C. psychostimulants
D. tricyclics (TCAs) - ANSWER-C. psychostimulants
Which medication may be the most helpful in reducing
flashbacks and nightmares associated with post-traumatic
stress disorder (PTSD)?
,2|Page
A. serotonergics (fluoxetine)
B. benzodiazepines (valium)
C. alpha-1 blockers (prazosin)
D. tricyclics (amitriptyline) - ANSWER-C. alpha-1 blockers
(prazosin)
Which of the following is not an accepted mechanism in the
development of depression?
A. epigenetics
B. pathological energy flow
C. glutamate excitotoxicity
D. resilience - ANSWER-D. resilience
The STAR*D trial demonstrated that:
A. the best approach for depression is to always begin with a
serotonin reuptake inhibitor
B. the chemical imbalance theory of depression is the best
explanation for the disorder
,3|Page
C. greater than 60% of patients will achieve remission from
depression within two adequate drug trials
D. the chance for remission decreases with each successive
antidepressant trial - ANSWER-D. the chance for remission
decreases with each successive antidepressant trial
Using information about a person's genetic makeup to choose
drugs and drug doses that are likely to work best for a particular
patient is called:
A. rational pharmacotherapy
B. pharmacodynamics
C. symptom-based medication selection
D. pharmacogenomics - ANSWER-D. pharmacogenomics
Which pharmacokinetic metabolizer phenotype breaks down
medications normally (has normal amounts of medication at
normal doses)?
A. Ultrarapid metabolizer
B. Extensive metabolizer
C. Intermediate metabolizer
, 4|Page
D. Poor metabolizer - ANSWER-C. Intermediate metabolizer
Which is one of the best-studied genes in all of psychiatry,
accounting for nearly 70% of the poor responses to selective
serotonin reuptake inhibitor (SSRI) medications?
A. HLA-A*3101
B. SLC6A4
C. CYP2D6
D. MTHFR - ANSWER-B. SLC6A4
Several clinical trials have examined the efficacy of
pharmacogenomically-informed treatment versus Treatment as
Usual. Which trial was the first Phase 3 study, including double-
blinding and placebo controls?
A. Pine Rest Study
B. Guided Study
C. Hamm Study
D. LaCrosse Study - ANSWER-B. Guided Study
FHEA Exam Newest 2026/2027 Verified Questions And Anwers
||Just Out!!!
Which pharmacogenomic marker helps to predict weight gain,
particularly related to the use of second generation
antipsychotics and other complex serotonergics?
A. SLC6A4
B. DRD2
C. 5HT2C
D. COMT - ANSWER-C. 5HT2C
All of the following medications may be therapeutic for Panic
Disorder, except:
A. serotonergics (SSRIs)
B. benzodiazepines (BZDs)
C. psychostimulants
D. tricyclics (TCAs) - ANSWER-C. psychostimulants
Which medication may be the most helpful in reducing
flashbacks and nightmares associated with post-traumatic
stress disorder (PTSD)?
,2|Page
A. serotonergics (fluoxetine)
B. benzodiazepines (valium)
C. alpha-1 blockers (prazosin)
D. tricyclics (amitriptyline) - ANSWER-C. alpha-1 blockers
(prazosin)
Which of the following is not an accepted mechanism in the
development of depression?
A. epigenetics
B. pathological energy flow
C. glutamate excitotoxicity
D. resilience - ANSWER-D. resilience
The STAR*D trial demonstrated that:
A. the best approach for depression is to always begin with a
serotonin reuptake inhibitor
B. the chemical imbalance theory of depression is the best
explanation for the disorder
,3|Page
C. greater than 60% of patients will achieve remission from
depression within two adequate drug trials
D. the chance for remission decreases with each successive
antidepressant trial - ANSWER-D. the chance for remission
decreases with each successive antidepressant trial
Using information about a person's genetic makeup to choose
drugs and drug doses that are likely to work best for a particular
patient is called:
A. rational pharmacotherapy
B. pharmacodynamics
C. symptom-based medication selection
D. pharmacogenomics - ANSWER-D. pharmacogenomics
Which pharmacokinetic metabolizer phenotype breaks down
medications normally (has normal amounts of medication at
normal doses)?
A. Ultrarapid metabolizer
B. Extensive metabolizer
C. Intermediate metabolizer
, 4|Page
D. Poor metabolizer - ANSWER-C. Intermediate metabolizer
Which is one of the best-studied genes in all of psychiatry,
accounting for nearly 70% of the poor responses to selective
serotonin reuptake inhibitor (SSRI) medications?
A. HLA-A*3101
B. SLC6A4
C. CYP2D6
D. MTHFR - ANSWER-B. SLC6A4
Several clinical trials have examined the efficacy of
pharmacogenomically-informed treatment versus Treatment as
Usual. Which trial was the first Phase 3 study, including double-
blinding and placebo controls?
A. Pine Rest Study
B. Guided Study
C. Hamm Study
D. LaCrosse Study - ANSWER-B. Guided Study
