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CSMLS Practice Exam 2026/2027 | Medical Laboratory Science Questions and Answers Study Guide

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This CSMLS study guide covers hematology, clinical chemistry, microbiology, transfusion medicine, coagulation, laboratory operations, professionalism, and quality management concepts. The material includes practice questions and answer explanations on iron studies, leukemia identification, microbiology culture interpretation, osmolality calculations, anticoagulants, blood banking procedures, and laboratory best practices. It is designed to support preparation for the Canadian Society for Medical Laboratory Science certification examination and reinforce core laboratory competencies.

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CSMLS Practice Exam 2026/2027 questions and
answers with complete solutions verified
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Terms in this set (191)



Which of the following conditions
correlates with results b)
IDA given below?


Iron:
Decreased
TIBC:
Increased
Ferritin:
Decreased
%Saturation: Decreased


a) Hemochromatosis
b) IDA
c) Chronic infection
d) Anemia of chronic disease

,Which of the following leukemias correlates
BEST given a) Chronic
myelomonocytic the following results?


WBC: 62.5 X 10⁹/L
Neutrophils: 39%
Lymphocytes: 2%
Monocytes: 48%
Eosinophils: 2%
Basophils: 0%
Metamyelocytes: 6%
Myelocytes: 2%
Blasts: 1%


a) Chronic myelomonocytic
b) Acute monoblastic
c) Acute myeloid
d) Chronic myelogenous

Which of the following conditions best
correlates with c) Food
poisonining the culture results below?


Aerobic blood agar colonial
morphology: large, beta-
hemolytic colonies Gram
stain: Gram positive spore

,forming bacilli


a) Brucellosis
b) Meningitis
c) Food poisoning
d) Atypical pneumonia




What is the molal freezing point of a
sample with an b) -
0.88°C osmolality of 475 mOsm/Kg?


a) -0.088°C
b) -0.88°C
c) 0.088°C
d) 0.88°C

, Which of the following
anticoagulants inhibits the c)
heparin conversion of prothrombin to
thrombin?


a) oxalate
b) citrate
c) heparin
d) EDTA

Which of the following results correlate with
primary b) BCR/ABL1
positive and 5% blasts identifications of chronic
myelogenous leukemia?


a) Philadelphia chromosome positive and 80% blasts
b) BCR/ABL1 positive and 5% blasts
c) Philadelphia chromosome negative and 5% blasts
d) BCR/ABL1 positive and 80% blasts

Which of the following actions should be taken when
a b) Participate on an
interprofessional team technologist is frustrated at
having to consistently explain
their profession to other healthcare professionals?


a) Refuse to offer an explanation
b) Participate on an interprofessional team

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