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RN Pharmacology A Exam | Practice Questions, Study Guide & Nursing Exam Prep 2026/2027

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RN Pharmacology A Exam | Practice Questions, Study Guide & Nursing Exam Prep 2026/2027

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RN Pharmacology A Questions with
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Which of the following medications is known to cause orange-colored urine? -
ANSWER-phenazopyridine (Pyridium)

You are ordered to give digoxin. Your patient's vital signs are as follows: Blood
Pressure 130/75, Temp 97.9 oral, HR 52, O2 Sat 100% room air. What should
you do next? - ANSWER-Hold digoxin and call the provider

Normal Saline (NS) is the solution of choice over D5W when preparing to
administer a blood transfusion because: - ANSWER-Normal Saline is an isotonic
solution and prevents cell hemolysis

Patient is to receive 5mg/kg of medication. Patient weighs 80kg. How much
would you administer? - ANSWER-400mg

Your patient taking digoxin (Lanoxin) has an AM Potassium level of 3.0. This
level may: - ANSWER-Increase risk of digoxin toxicity

The patient is diagnosed with multiple myeloma. The physician has ordered
cyclophosphamide (Cytoxan). Which instruction should be given to the patient? -
ANSWER-Increase daily water intake

Which of the following medications will crystalize when mixed with D5NS? -
ANSWER-phenytoin (Dilantin)

Which of the following medications should be questioned by the nurse, if ordered
by the provider to treat a patient's complaint of nausea and vomiting? -
ANSWER-famotidine (Pepcid)

,Your patient has an epidural infusing hydromorphone with bupivacaine at 6ml/hr
continuously. The patient's blood pressure at the beginning of your shift was
92/58 with a heart rate of 68. You noticed the patient's blood pressures have
been around 130/70. What should you do FIRST? - ANSWER-Check infusion
rate to confirm 6ml/hr, then notify anesthesia provider

The dosage of which drug must be tapered off slowly to prevent acute adrenal
insufficiency? - ANSWER-prednisone (Deltasone)

When teaching a new nurse on how to administer IV push furosemide (Lasix),
you emphasize that it should be given over two minutes to avoid: -
ANSWER-tinnitus

A nurse is caring for a patient with hyperparathyroidism and notes that the
patient's serum calcium level is 13mg/dl. Which medication should the nurse
prepare to administer as prescribed to the patient? - ANSWER-calcintonin
(Miacalcin)

A patient has a prescription to take Guaifenesin (Mucinex) every 4 hours, as
needed. The nurse determines that the patient understands the MOST effective
use of the medication if the patient states that he or she will: - ANSWER-take the
medication with a full glass of water

Acetylsalicylic acid (Aspirin) has which of the following pharmacological effects? -
ANSWER-Anti-inflammatory, anti-pyretic, decrease platelet aggregation

Your patient is to receive 2 G vancomycin over 2 hours. The medication comes in
from the pharmacy as 2 G Vancomycin in 250ml normal saline. At what rate will
the IV medication run? - ANSWER-125ml/hr

Sildenafil (Viagra) is prescribed to treat a patient with erectile dysfunction. A
nurse reviews the patient's medical record and would question the prescription if
which of the following is noted in the history? - ANSWER-Use of nitroglycerin

While delivering the lunch tray of a patient who is taking warfarin (Coumadin), the
nurse notices diversity of food items. Which of the following foods would be a
concern? - ANSWER-Spinach

, Your patient is receiving vancomycin (Vancocin) 500mg IV every 12 hours. As a
nurse, you understand that the PRIMARY rationale for monitoring serum levels of
vancomycin is that: - ANSWER-It can cause nephrotoxicity

Convert 1.2 milligrams to micrograms - ANSWER-1200 mcg

When caring for a patient with a central line who is receiving TPN, what is the
MOST important action on the part of the nurse to prevent CLABSI? -
ANSWER-wrong answer: Change IV tubing and perform CVC dressing on
patient every 36 hours

You are caring for a patient with diabetes. Humalog insulin is ordered via sliding
scale AC and HS. When is the best time to administer Humalog insulin? -
ANSWER-15 minutes before meal arrives

A provider orders one liter of NS to be infused over four hours. At what rate
would you set the IV pump? - ANSWER-250ml/hr

Which medication is used to treat iron toxicity? - ANSWER-deferoxamine
(Digibind)

Your patient presents with CHF and has a Potassium level of 5.8. Which diuretic
do you anticipate being ordered by the provider? - ANSWER-bumetanide
(Bumex)

Your patient is on a Morphine PCA after a recent exploratory surgery. While
doing your rounds, you notice that your patient is slumped over, unresponsive,
with delayed and slow respirations. You suspect narcotic overdose. Which
reversal medication would you administer? - ANSWER-naloxone (Narcan)

A patient's capillary blood glucose reading is 33mg/dl. Which of the following
medications will the nurse administer if the patient is unable to tolerate PO? -
ANSWER-Dextrose 50% IV push

When a patient has pernicious anemia, the nurse would expect to give them: -
ANSWER-Vitamin B12

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