180 Verified Questions & 100% Verified Answers | Guaranteed First
Attempt Pass! PROCTORED EXAM STUDY GUIDE Latest 2025/2026
Update (exam Questions with correct answers and Rationales)
,
,SECTION I: Pharmacokinetics & Pharmacodynamics
(Questions 1-25)
, Question 1
A nurse is preparing to administer a medication to a patient with a history of liver
disease. The nurse understands that this patient may have impaired:
A) Absorption
B) Distribution
C) Metabolism
D) Excretion
Correct Answer: C
Rationale: The liver is the primary site of drug metabolism. Liver disease can impair
drug metabolism, leading to drug accumulation and toxicity. Doses may need to be
adjusted. Absorption is primarily affected by GI function, distribution by protein binding,
and excretion by renal function.
Question 2
A patient with renal impairment is receiving a medication that is primarily excreted by the
kidneys. The nurse should monitor for:
A) Decreased drug effect
B) Increased drug effect and toxicity
C) No change in drug effect
D) Allergic reaction
Correct Answer: B
Rationale: When renal function is impaired, drugs that are primarily excreted by the
kidneys can accumulate, leading to increased drug effects and toxicity. Doses may need
to be adjusted based on creatinine clearance.