, 2|Page
Test Bank for Applied Pathophysiology A
Conceptual Approach 4th Edition by Judi
Nath – Complete Chapter 1-20 Question
Bank with Rationales
Table of Contents
1. Introduction to Pathophysiology
2. Altered Cells and Tissues
3. Inflammation and Tissue Repair
4. Altered Immunity
5. Infection
6. Genetic and Developmental Disorders
7. Altered Cellular Proliferation and Differentiation
8. Altered Fluid and Electrolyte Balance
9. Altered Acid–Base Balance
10. Altered Neural Function
11. Altered Mood, Attention, and Behavior
12. Altered Somatic and Special Sensory Function
13. Altered Hormonal and Metabolic Regulation
14. Altered Reproductive Function
15. Altered Ventilation and Diffusion
16. Altered Perfusion
17. Altered Nutrition
18. Altered Elimination
19. Degenerative Changes in Aging
20. Integrated Pathophysiology
, 3|Page
Chapter 1: Introduction to Pathophysiology
1. Which term is defined as the study of the mechanisms of human body functioning?
a. Pathology
b. Physiology
c. Anatomy
d. Pathophysiology
ANS: B
Physiology is the study of the mechanisms of human body functioning.
Pathology is the study of changes in cells and tissues as a result of injury or
disease. Anatomy is the study of body structures. Pathophysiology is the study
of mechanisms of disease.
2. A nurse is studying how a patient's disease develops over time. Which aspect of
pathophysiology is being examined?
a. Etiology
b. Pathogenesis
c. Clinical manifestations
d. Prognosis
ANS: B
Pathogenesis refers to the sequence of events in the development of a disease.
, 4|Page
Etiology is the cause of disease, clinical manifestations are the signs and
symptoms, and prognosis is the predicted outcome.
3. Which of the following is an example of a congenital condition?
a. Influenza infection
b. Fractured femur from a fall
c. Cystic fibrosis
d. Streptococcal pharyngitis
ANS: C
Cystic fibrosis is a genetic disorder present at birth (congenital). Influenza and
streptococcal pharyngitis are infectious diseases, and a fractured femur from a
fall is an acquired injury.
4. A patient presents with fever, headache, and fatigue. These findings are best
described as:
a. Signs
b. Symptoms
c. Syndrome
d. Sequelae
ANS: B
Symptoms are subjective complaints reported by the patient (headache,
fatigue). Signs are objective findings that can be measured (fever). A syndrome
is a collection of signs and symptoms, and sequelae are complications that
follow a disease.
5. Which of the following best defines the term "etiology"?
a. The study of disease mechanisms
b. The cause of a disease
c. The predicted outcome of a disease
d. The structural changes in cells
ANS: B
Etiology is defined as the cause or origin of a disease. Pathophysiology is the