IMSEP PRELIMS Questions with 100%
Verified Correct Answers
Immunology
- Is the branch of biomedical science concerned with the study of the immune system, its
structure, functions, and disorders.
- It encompasses the mechanisms by which the body recognizes and defends against foreign
substances(antigens) , pathogens, and abnormal cells
Serology
The branch of science dealing with the measurement and characterization of antibodies,
antigens and other immunological substances in the body fluids or serum .
serum
latin: sero
Thucydides
- concept of immunity | greece, 5th century BC
- he wrote individuals who recovered
from the plague became "immune" or "exempt."
Variolation
- a practice that exposes an individual to a material, lesions or scabs
- early method to protect people against small pox
Chinese (1500's)
inhalation of powdered smallpox lesions / scabs
,1. inoculation through skin (cutaneous variolation)
2. inhalation (respiratory variolation)
two methods of variolation
Lady Mary Wortley Montagu
- pioneer of variolation practices
- championed variolation's benefits, introducing to England after observing its success in
the Ottoman Empire
Charles Maitland
was given leave to perform what came to be known as the Royal Experiment, in which he
Variolated six condemned prisoners who later survived.
Edward Jenner
- observed that milkmaids (udders) who contracted cowpox appeared immune to smallpox.
1796
Edward Jenner inoculated James Phipps with cowpox material, then exposed him to smallpox
- the boy did not develop the disease, proving the protective effect.
Edward Jenner
- foundation for modern vaccines
- vaccine (from latin vacca, meaning cow)
vaccination
is the process of deliberately exposing the body to a harmless form of a pathogen (or parts of
it) to stimulate the immune system and build protection against future infection.
,Germ Theory
revolutionized immunology by establishing that microorganisms
cause infectious diseases. Pasteur demonstrated that specific pathogens are responsible for
specific diseases, laying the foundation for modern immunology and vaccinology.
Rabies Vaccine (1885)
Pasteur developed the first successful rabies vaccine, tested
on humans after animal trials.
Anthrax Vaccine (1881)
Pasteur publicly demonstrated anthrax vaccine efficacy in
livestock, proving vaccination's practical value.
Pasteurization
Proved microorganisms cause fermentation and spoilage,
advancing germ theory.
Edward Jenner, 1798
discovery - smallpox vaccination
Louise Pasteur, 1880-1881
Live, attenuated chicken cholera and anthrax vaccines
Elie Metchnikoff, 1883–1905
Cellular theory of immunity through phagocytosis
Louis Pasteur, 1885
, - Therapeutic vaccination
- First report of live "attenuated" vaccine for rabies
Emil von Behring, Shibasaburo Kitasato, 1890
Humoral theory of immunity proposed
Robert Koch, 1891
Demonstration of cutaneous (delayed-type) hypersensitivity
Jules Bordet, 1894
Complement
Robert Kaus, 1897
Precipitation
Paul Ehrlich, 1900
Antibody formation theory
Charles Richet, 1902
Immediate-hypersensitivity
Paul Portier, 1902
Anaphylaxis
Maurice Arthus, 1903
Arthus reaction of intermediate hypersensitivity
Wright and Douglas, 1903
- Opsonization
Verified Correct Answers
Immunology
- Is the branch of biomedical science concerned with the study of the immune system, its
structure, functions, and disorders.
- It encompasses the mechanisms by which the body recognizes and defends against foreign
substances(antigens) , pathogens, and abnormal cells
Serology
The branch of science dealing with the measurement and characterization of antibodies,
antigens and other immunological substances in the body fluids or serum .
serum
latin: sero
Thucydides
- concept of immunity | greece, 5th century BC
- he wrote individuals who recovered
from the plague became "immune" or "exempt."
Variolation
- a practice that exposes an individual to a material, lesions or scabs
- early method to protect people against small pox
Chinese (1500's)
inhalation of powdered smallpox lesions / scabs
,1. inoculation through skin (cutaneous variolation)
2. inhalation (respiratory variolation)
two methods of variolation
Lady Mary Wortley Montagu
- pioneer of variolation practices
- championed variolation's benefits, introducing to England after observing its success in
the Ottoman Empire
Charles Maitland
was given leave to perform what came to be known as the Royal Experiment, in which he
Variolated six condemned prisoners who later survived.
Edward Jenner
- observed that milkmaids (udders) who contracted cowpox appeared immune to smallpox.
1796
Edward Jenner inoculated James Phipps with cowpox material, then exposed him to smallpox
- the boy did not develop the disease, proving the protective effect.
Edward Jenner
- foundation for modern vaccines
- vaccine (from latin vacca, meaning cow)
vaccination
is the process of deliberately exposing the body to a harmless form of a pathogen (or parts of
it) to stimulate the immune system and build protection against future infection.
,Germ Theory
revolutionized immunology by establishing that microorganisms
cause infectious diseases. Pasteur demonstrated that specific pathogens are responsible for
specific diseases, laying the foundation for modern immunology and vaccinology.
Rabies Vaccine (1885)
Pasteur developed the first successful rabies vaccine, tested
on humans after animal trials.
Anthrax Vaccine (1881)
Pasteur publicly demonstrated anthrax vaccine efficacy in
livestock, proving vaccination's practical value.
Pasteurization
Proved microorganisms cause fermentation and spoilage,
advancing germ theory.
Edward Jenner, 1798
discovery - smallpox vaccination
Louise Pasteur, 1880-1881
Live, attenuated chicken cholera and anthrax vaccines
Elie Metchnikoff, 1883–1905
Cellular theory of immunity through phagocytosis
Louis Pasteur, 1885
, - Therapeutic vaccination
- First report of live "attenuated" vaccine for rabies
Emil von Behring, Shibasaburo Kitasato, 1890
Humoral theory of immunity proposed
Robert Koch, 1891
Demonstration of cutaneous (delayed-type) hypersensitivity
Jules Bordet, 1894
Complement
Robert Kaus, 1897
Precipitation
Paul Ehrlich, 1900
Antibody formation theory
Charles Richet, 1902
Immediate-hypersensitivity
Paul Portier, 1902
Anaphylaxis
Maurice Arthus, 1903
Arthus reaction of intermediate hypersensitivity
Wright and Douglas, 1903
- Opsonization
