Proctored Exam Preparation Study Guide Featuring
a Full Set of 200 Next-Generation NCLEX-Style
Practice Questions with Detailed Rationales and
Explanations Covering Cardiovascular, Endocrine,
Respiratory, Psychiatric, Antibiotic, GI, and Clinical
Judgment Topics for Nursing Students.
SECTION I: GENERAL PHARMACOLOGY & SAFETY
(Questions 1-20)
1. Which medication classification inhibits bacterial
cell wall synthesis?
• A. Macrolides
• B. Cephalosporins
• C. Tetracyclines
• D. Aminoglycosides
, • ☑VERIFIED ANSWERS: B. Cephalosporins
• Rationale: Cephalosporins interfere with
bacterial cell wall synthesis, leading to cell lysis.
2. A nurse is preparing to administer an IM
injection to an adult. Which needle gauge and
length is most appropriate for a deep IM injection
into the ventrogluteal muscle?
• A. 25-gauge, 5/8-inch
• B. 20-gauge, 1.5-inch
• C. 18-gauge, 2-inch
• D. 27-gauge, 1/2-inch
• ☑VERIFIED ANSWERS: B. 20-gauge, 1.5-inch
• Rationale: A 20- to 22-gauge, 1.5-inch needle is
standard for deep IM injections in the
ventrogluteal site to ensure deposition into the
muscle belly.
, 3. A nurse receives a verbal order: "Give morphine
4 mg IV push now." What should the nurse do
first?
• A. Administer the medication immediately.
• B. Read back the complete order to the provider
for confirmation.
• C. Document the order in the EHR.
• D. Ask a second nurse to witness the order
entry.
• ☑VERIFIED ANSWERS: B. Read back the
complete order to the provider for
confirmation.
• Rationale: For verbal/telephone orders, the
nurse must perform a read-back of the full
prescription to prevent errors.
4. A client with end-stage renal disease is
prescribed a medication primarily excreted by the
kidneys. The nurse should recognize this client is at
highest risk for which outcome?