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PAEA Pediatrics EOR Topics
2026|Certified Questions And
Answers
a drug reaction caused by immune antibody-antigen complex deposition is a type
___ hypersensitivity rxn - correct-answer - type III
a delayed (cell mediated) drug reaction like erythema multiforme is a type ___
hypersensitivity rxn - correct-answer - type IV
what is the most common type of cutaneous drug eruption? tx? - correct-answer
- exanthematous/morbiliform rash- generalized distribution of "bright-red"
macules & papules that coalesce to form plaques- usually begins 2-14 days after
medication initiation (abx, NSAIDs, allopurinol, thiazide diuretics)
tx: oral antihistamines
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what is the 2nd Mc type of cutaneous drug eruption that occurs w/i minutes to
hrs after drug administration? tx? - correct-answer - urticarial or angioedema
(type I)- triggers include abx, NSAIDs, opiates, radiocontrast media
tx: systemic corticosteroids, antihistamines
what is the 3rd MC cutaneous drug eruption that is characterized by target
lesions? tx? - correct-answer - erythema multiforme (type IV)- triggered by
sulfonamines, PCNs, phenobarbital, dilantin
tx: symptomatic therapy
in regards to urticaria, local pinpoint pressure that results in the skin to wheal in
that area is called? local rubbing causing urticaria is called? - correct-answer -
dermatographism
Darier's sign
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how is urticaria treated? - correct-answer - removal of offending agent,
antihistamines (H1 blockers), corticosteroids, or H2 blockers as adjuvant therapy
(cimetidine, ranitidine, famoidine)
erythema multiforme is MC associated with - correct-answer - *HSV*,
mycoplasma, s. pneumo, sulfa drugs, beta-lactams, phenytoin, phenobarbital,
malignancies, autoimmune
red purpuric papules and macules with a hypopigmented rim around the center
and a erythematous halo around that span the palms and soles of the feet? same
lesions but involving 1 or more mucous membranes (oral, genital, or ocular
mucosa) and <10% BSA with no epidermal detachment. - correct-answer -
erythema multiforme minor; major
what is the treatment for erythema multiforme? - correct-answer - symptomatic-
d/c offending drug, antihistamines, analgesics,
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steroid/lidocaine/diphenhydramine mouthwash for oral lesions, and systemic
steroids if severe
Steven-Johnson Syndrome and TEN are usually due to what offending agents? -
correct-answer - MC d/t drug eruptions from *sulfa*, *anticonvulsants*, NSAIDs,
allopurinol, abx, infxns like mycoplasma, HIV, HSV, malignancy, or idiopathtic
SJS is defined as sloughing of ____% BSA where are TEN is defined as sloughing of
____% BSA - correct-answer - SJS <10%
TEN >30%
Dx? fever, URI, widespread blisters, erythematous/pruritic papules with 1 or more
mucous membranes involved with epidermal detachment (+ Nikolsky sign), <10%
BSA; tx? - correct-answer - dx: SJS (if >30% = TEN)
tx: treat like severe burn- admit to burn unit, pain control, withdrawal of
offending meds, fluid & electrolyte replacement, wound care
PAEA Pediatrics EOR Topics
2026|Certified Questions And
Answers
a drug reaction caused by immune antibody-antigen complex deposition is a type
___ hypersensitivity rxn - correct-answer - type III
a delayed (cell mediated) drug reaction like erythema multiforme is a type ___
hypersensitivity rxn - correct-answer - type IV
what is the most common type of cutaneous drug eruption? tx? - correct-answer
- exanthematous/morbiliform rash- generalized distribution of "bright-red"
macules & papules that coalesce to form plaques- usually begins 2-14 days after
medication initiation (abx, NSAIDs, allopurinol, thiazide diuretics)
tx: oral antihistamines
,2|Page
what is the 2nd Mc type of cutaneous drug eruption that occurs w/i minutes to
hrs after drug administration? tx? - correct-answer - urticarial or angioedema
(type I)- triggers include abx, NSAIDs, opiates, radiocontrast media
tx: systemic corticosteroids, antihistamines
what is the 3rd MC cutaneous drug eruption that is characterized by target
lesions? tx? - correct-answer - erythema multiforme (type IV)- triggered by
sulfonamines, PCNs, phenobarbital, dilantin
tx: symptomatic therapy
in regards to urticaria, local pinpoint pressure that results in the skin to wheal in
that area is called? local rubbing causing urticaria is called? - correct-answer -
dermatographism
Darier's sign
,3|Page
how is urticaria treated? - correct-answer - removal of offending agent,
antihistamines (H1 blockers), corticosteroids, or H2 blockers as adjuvant therapy
(cimetidine, ranitidine, famoidine)
erythema multiforme is MC associated with - correct-answer - *HSV*,
mycoplasma, s. pneumo, sulfa drugs, beta-lactams, phenytoin, phenobarbital,
malignancies, autoimmune
red purpuric papules and macules with a hypopigmented rim around the center
and a erythematous halo around that span the palms and soles of the feet? same
lesions but involving 1 or more mucous membranes (oral, genital, or ocular
mucosa) and <10% BSA with no epidermal detachment. - correct-answer -
erythema multiforme minor; major
what is the treatment for erythema multiforme? - correct-answer - symptomatic-
d/c offending drug, antihistamines, analgesics,
, 4|Page
steroid/lidocaine/diphenhydramine mouthwash for oral lesions, and systemic
steroids if severe
Steven-Johnson Syndrome and TEN are usually due to what offending agents? -
correct-answer - MC d/t drug eruptions from *sulfa*, *anticonvulsants*, NSAIDs,
allopurinol, abx, infxns like mycoplasma, HIV, HSV, malignancy, or idiopathtic
SJS is defined as sloughing of ____% BSA where are TEN is defined as sloughing of
____% BSA - correct-answer - SJS <10%
TEN >30%
Dx? fever, URI, widespread blisters, erythematous/pruritic papules with 1 or more
mucous membranes involved with epidermal detachment (+ Nikolsky sign), <10%
BSA; tx? - correct-answer - dx: SJS (if >30% = TEN)
tx: treat like severe burn- admit to burn unit, pain control, withdrawal of
offending meds, fluid & electrolyte replacement, wound care
