ADVANCED PATHOPHYSIOLOGY MIDTERM 6501 WALDEN UNIVERSITY LATEST 2026/2027 ACTUAL EXAM QUESTIONS WITH CORRECT ANSWERS 100% VERIFIED GRADED A+

ADVANCED PATHOPHYSIOLOGY
MIDTERM NUR 6501 WALDEN
UNIVERSITY / COMPLETE ACTUAL
EXAM / 150+ QUESTIONS AND
CORRECT DETAILED ANSWERS /
2025/2026
Am4-year-
oldmchildmappearsmlistlessmformthemlastmweek.mHemcomplainsmofmpainmwhenmhemismpickedmupmbymhi
smmother,mandmhemismirritablemwhenmtouchingmhismarmsmormlegs.mSeveralmlargemecchymoticmlesions
mhavemappearedmonmhismrightmthighmandmleftmshoulder.mAmcompletembloodmcountmrevealsmamHgB=1


0.2,mHct=30.5%,mMCV=96fL,mplateletmcountmofm45,000/ML,mandmWBCmcountmofm13,990/ML.mExa
minationmofmthemperipheralmbloodmsmearmrevealsmnumerousmblasts.mThemblastsmlackmperoxidase-
positivemgranulesmbutmdomcontainmperiodicmacid-Schiffm(PAS)-
positivemaggregatesmandmstainmpositivelymformTdT.mFlowmcytometrymshowsmthemphenotypemofmblas
tsmtombemCD19+,mCD3-,mandmsIg-.mWhatmismthemmostmlikelymdiagnosis?



A.mAcutemlymphoblasticmleukemiam(ALL)

B.mChronicmlymphocyticmleukemiam(CLL)

C.mAcutemmyelogenousmleukemiam(AML)

D.mChronicmmyelogenousmleukemiam(CML)m-mCORRECTmANSWERmAcutemlymphblasticmleukemia



Am3-year-
oldmchildmofmItalianmancestrympresentsmwithmfailuremtomthrive.mPhysicalmexaminationmindicatesmhe
patosplenomegaly.mHismhemoglobinmconcentrationmism6mg/dL,mandmthemperipheralmbloodmsmearmr
evealsmseverelymhypochromicmmicrocyticmredmcells.mTotalmserummironmlevelmismnormal.mThemreticul
ocytemcountmism10%.mHemoglobinmelectrophoresismshowsmverymlittlemhemoglobinmA.mAmradiograp
hmofmthemskullmshowsmmaxillofacialmdeformities.mWhatmismthemprinciplemcausemofmanemiamandmoth
ermabnormalitiesminmthismpatient?



A.mReducedmsynthesismofmhemoglobinmF

,B.mReducedmredmbloodmcellmsurvivalmfrommimbalanceminmthemproductionmofmalphamandmbetamglobi
nmchains

C.mRelativemdeficiencymofmvitaminmB12

D.mIncreasedmfragilitymofmthemerythrocytemmembranem-
mCORRECTmANSWERmReducedmsynthesismofmhemoglobinmF




Am68-year-
oldmpreviouslymhealthymfemalemhasmbeenmfeelingmincreasinglymtiredmandmweakmformseveralmmonth
s.mShemstatesmthatmshemhasmhadmblack,mtarrymstoolsmformseveralmweeks.mShemismfoundmtombemanemi
cmwithmamhemoglobinmconcentrationmofm9.3g/dL.mThemperipheralmbloodmsmearmrevealsmmicrocytic
mandmhypochromicmbloodmcells.mWhichmofmthemfollowingmconditionsmshouldmbemsuspectedmasmthem


mostmlikelymofmhermconditionmasmindicatedmbymthemperipheralmbloodmsmear?



A.mAplasticmanemia

B.mBetamthalassemia

C.mGastrointestinalmbloodmloss

D.mPerniciousmanemiam-mCORRECTmANSWERmGastrointestinalmbloodmloss



Am76-year-
oldmfemalemnoticesmthatmsmall,mpinpointmtomblotchymareasmofmsuperficialmhemorrhagemhavemappe
aredmonmhermgumsmandmonmthemskinmofmhermarmsmandmlegsmovermseveralmweeks.mShemismfoundmtom
havemamnormalmprothrombinmtime(PT)mandmpartialmthromboplastinmtimem(PTT).mHermCBCmshowsm
hemoglobinmconcentrationmofm12.7mg/dL,mhematocritmofm37.2%.mMCVmofm80mfL/redmcell,mplateletm
countmofm276,000/microliter,mandmWBCmofm5600/microliter.mHermtemplatembleedingmtimemism3mmi
nutes.mHermfibrinogenmlevelmismnormal,mandmtheremaremnomfibrinmsplitmproductsmdetectable.mWhic
hmofmthemfollowingmconditionsmbestmexplainmthesemfindings?



A.mChronicmrenalmfailure

B.mMacronodularmcirrhosis

C.mVitaminmB12mdeficiency

,D.mVitaminmCmdeficiencym-mCORRECTmANSWERmVitaminmCmdeficiency



AmyoungmadultmpatientmhasmjustmbeenmdiagnosedmwithmVonmWillebrandmdisease.mWhichmofmthemfo
llowingmstatementsmshouldmyoummakemtomadvisemthempatientmofmpotentialmconsequencesmofmthism
disease?



A.mYoummaymneedmanmallogeneicmbonemmarrowmtransplant

B.mYoummaymhavemexcessivembleedingmfollowingmtoothmextraction

C.mAmsplenectomymmaymbemnecessarymtomcontrolmthemdisease

D.mExpectmincreasingmdifficultiesmwithmjointmmobilitym-
mCORRECTmANSWERmYoummaymhavemexcessivembleedingmfollowingmtoothmextraction




Lowmdosemaspirinmismcommonlymusedmtomreducemthemriskmofmarterialmthrombosisminmpatientsmwho
mhavemsufferedmammyocardialminfarction.mWhichmonemofmthemfollowingmstepsminmhomeostasismismin


hibitedmbymaspirin?



A.mSynthesismofmvonmWillebrandmfactor

B.mAggregationmofmplatelets

C.mActivationmofmfactormXa

D.mSynthesismofmantithrombinmIIIm-mCORRECTmANSWERmAggregationmofmplatelets



Am24-year-
oldmpresentsmtomthemofficemwithmfatigue.mOnmphysicalmexam,mthemNPmnoticesmthatmshemispalemwith
mthemfollowingmvitalmsigns:mHRm112,mBPm98/64,mrespm20,mO2msatsm99%.mHermCBCmshows:mWBC6,00


0,mHemoglobinm9.6,mHematocritm30.2,mMCVmismdecreasedmatm76.mWhatmismthemmostlymlikelymcause
ofmthismpatient'smanemia?



A.mIronmdeficiencymanemiamcausedmbymmenstruation

B.mBetamThalassemiamofmgeneticmorigin

, C.mPerniciousmanemiamcausedmbymdietarymdeficiency

D.mFolatemdeficiencymcausedmbymalcoholismm-
mCORRECTmANSWERmIronmdeficiencymanemiamcausedmbymmenstruation




Am65-year-
oldmfemalempresentsmtomyourmofficemcomplainingmofmfatigue.mShemhasmamlongmofmrheumatoidmarth
ritis.mAmCBCmrevealsmthemfollowing:mHgb=11.6mg/dL,mHct=34.8%,mMCV=87mfL/redmcell,mplateletmco
untmofm268,000/microliter,mandmWBCmcountmofm6800/microliter.mThemserummhaptoglobinmlevelmism
normal,mandmthemserummironmconcentrationmism20mmicrograms/dL.mThemtotalmironmbindingmcapaci
tymism195mmicrograms/dL,mandmthempercentmsaturationmism10.2.mThemserummferritinmconcentration
mism317mng/mL.mNomfibrinmsplitmproductsmaremdetected.mThemreticulocytemconcentrationmism1.1%.m


Whatmismthemmostmlikelymdiagnosis?



A.mBeta-mthalassemiammajor

B.mAnemiamofmchronicmdiseasem

C.mAcutembloodmlossmanemia

D.mIronmdeficiencymanemiam-mCORRECTmANSWERmAnemiamofmchronicmdisease



Am14-year-
oldmmalempresentsmwithmhighmfevermformtenmdays.mPhysicalmexaminationmrevealsmscatteredmpetech
ialmhemorrhagesmbutmismnegativemformenlargementmofmthemlivermormspleenmormlymphmnodes.mBone
mmarrowmexaminationmdoesmnotmshowmanymabnormalmcells.mThemcompletembloodmcountm(CBC)mde


monstratesmamhemoglobinmconcentrationm(HgB)mofm13.2mg/dL,mhematocritm(Hct)mofm38.9%,mmean
mcellmvolumem(MCV)mofm93mfL,mplateletmcountmofm175,000/microliter,mandmwhitembloodmcellm(WBC)


mcountmofm1850/microliter,mwithmthemdifferentialmcountmshowingm1msegmentedmneutrophil,m98mly


mphocytes,mandm1mmonocytemperm100mWBCs.mWhatmismthemmostmlikelymcausemofmthesemfindings?



A.mOverwhelmingmbacterialminfection

B.mAcutemlymphocyticm(ormlymphoblastic)mleukemia

C.mAcutemmyeloidmleukemia

D.mAplasticmanemiam-mCORRECTmANSWERmOverwhelmingmbacterialminfection