2026/2027 | PRACTICE QUESTIONS &
VERIFIED ANSWERS | COMPLETE EPIC
ORDER TRANSMITTAL STUDY GUIDE
CLN500 ORDER TRANSMITTAL EXAM 2026/2027
PRACTICE QUESTIONS & VERIFIED ANSWERS | COMPLETE EPIC ORDER
TRANSMITTAL STUDY GUIDE
DOCUMENT OVERVIEW
• This comprehensive study guide contains 200 verified practice questions covering
all aspects of EPIC Order Transmittal processes, clinical workflows, and system best
practices for healthcare professionals.
• Use this material for exam preparation by reviewing each question, attempting
answers independently, then checking your responses against the provided
rationales to reinforce learning and identify knowledge gaps.
1. QUESTION: What is the primary purpose of the Order Transmittal system in
EPIC?
A) To archive patient medical records from previous years
B) To facilitate the creation, management, and communication of clinical orders
throughout the healthcare organization
C) To generate billing invoices for insurance companies
D) To store patient demographic information only
E) To manage human resources and payroll operations
CORRECT ANSWER: B
,Rationale: The Order Transmittal system in EPIC is specifically designed to facilitate
the creation, management, and communication of clinical orders (medications, labs,
imaging, procedures, etc.) throughout the healthcare organization. This system
ensures orders are properly routed to the appropriate departments (pharmacy,
laboratory, imaging) and tracked until completion. While archiving and
demographic storage are functions within EPIC, they are not the primary purpose
of the Order Transmittal system. Billing and HR functions fall outside the scope of
clinical order management.
2. QUESTION: Which of the following is the first critical step when initiating a
new order in EPIC?
A) Immediately send the order to the pharmacy or lab without verification
B) Verify patient identity and ensure the correct patient record is open
C) Skip the safety checks to expedite the process
D) Assume the previous order information is still accurate
E) Close the patient chart before creating the order
CORRECT ANSWER: B
Rationale: Patient verification is the foundational safety step in any clinical order.
Before creating any order, you must confirm you are working in the correct
patient's record by verifying patient identifiers (name, date of birth, medical record
number). This prevents medication errors and ensures orders are transmitted to
the right patient. Skipping verification steps, sending orders without checks, or
making assumptions about patient records compromise patient safety and violate
clinical protocols.
3. QUESTION: What does the Clinical Decision Support (CDS) feature in EPIC
Order Transmittal provide?
A) Only demographic data about patients
,B) Real-time alerts and guidance to prevent potential medication and order safety
issues
C) Financial information about hospital billing
D) Administrative employee schedules
E) Historical weather data
CORRECT ANSWER: B
Rationale: Clinical Decision Support (CDS) is a critical safety feature in EPIC that
provides real-time alerts and guidance when ordering medications or treatments.
CDS alerts clinicians to potential drug-drug interactions, allergies, contraindications,
dosing errors, and other clinical concerns. This feature helps prevent adverse
events and improves patient safety by catching potential problems before orders
are finalized and transmitted. The other options do not relate to clinical decision
support functions.
4. QUESTION: When modifying an existing order in EPIC, what is the
recommended practice?
A) Modify the original order and immediately send it without review
B) Create a new order and cancel the old one to maintain an audit trail of changes
C) Delete the original order entirely to avoid confusion
D) Ignore the old order and create multiple duplicate orders
E) Change the order in the pharmacy system directly
CORRECT ANSWER: B
Rationale: When modifying orders, creating a new order and canceling the original
maintains a complete audit trail in EPIC, which is essential for legal, safety, and
quality purposes. This approach allows providers to see what the original order
was, when it was changed, and why. Modifying without review, deleting records,
creating duplicates, or bypassing the EPIC system violates documentation
standards and compromises the integrity of the medical record.
, 5. QUESTION: Which patient information must always be verified before
transmitting an order?
A) Patient's favorite color and preferred music
B) Patient name, date of birth, medical record number, and current location
C) Only the patient's first name
D) The patient's insurance company exclusively
E) The patient's social media usernames
CORRECT ANSWER: B
Rationale: Patient name, date of birth (DOB), medical record number (MRN), and
current location are critical identifiers that must always be verified before
transmitting any order. These identifiers ensure the order reaches the correct
patient and prevent wrong-patient errors. The other options either contain
irrelevant information or use only partial identifiers that could lead to serious
clinical errors.
6. QUESTION: What should you do if you receive a CDS alert about a potential
drug-drug interaction while placing a medication order?
A) Ignore the alert and send the order anyway
B) Close the alert without reading it completely
C) Review the alert carefully, consult with the prescribing provider if needed, and
make an informed decision before proceeding
D) Assume the system is wrong and override it without documentation
E) Delete the alert from the system
CORRECT ANSWER: C
Rationale: When a CDS alert appears, especially for drug-drug interactions, the
appropriate response is to review the alert thoroughly. You should consult with the