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MCAT 2026–2027 – Medical College Admission Test – Complete Exam Study Guide with Questions and Correct Answers

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This MCAT 2026–2027 study guide contains exam questions with answers covering major MCAT science topics, including general chemistry, organic chemistry, biochemistry, physics, and cell and molecular biology. The material reviews atomic structure, acids and bases, electrochemistry, organic reactions, DNA and RNA, amino acids and proteins, enzyme kinetics, metabolism, mechanics, fluids, electricity, waves, membranes, organelles, cell signaling, and the cell cycle. Presented primarily in question-and-answer format, the 97-page document is designed for focused MCAT review and exam preparation. Keywords MCAT MCAT exam questions and answers MCAT study guide MCAT practice questions MCAT test prep MCAT exam preparation MCAT chemistry review MCAT organic chemistry MCAT biochemistry review MCAT physics review MCAT biology review MCAT cell biology MCAT molecular biology amino acids and proteins enzyme kinetics DNA replication and transcription cellular metabolism glycolysis and Krebs cycle acid base chemistry electrochemistry review organic chemistry reactions mechanics and fluids electricity and circuits cell signaling medical school admission test

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MCAT EXAM STUDY GUIDE
2026-2027 Exam Questions
with 100% Correct Answers |
Latest Update



What is the aufbau principle? - ANSWER ✔✔Electrons fill orbitals

starting from the lowest energy level to the highest energy level


What is Hund's rule? - ANSWER ✔✔Electrons fill degenerate orbitals

singly before pairing up, and all unpaired electrons have parallel spins


What is the Pauli exclusion principle? - ANSWER ✔✔No two

electrons in an atom can have the same four quantum numbers

,What are the four quantum numbers? - ANSWER ✔✔Principal (n),

angular momentum (l), magnetic (ml), and spin (ms)


What does the principal quantum number (n) represent? - ANSWER

✔✔Energy level and size of the orbital; n = 1, 2, 3, etc.


What does the angular momentum quantum number (l) represent? -

ANSWER ✔✔Shape of the orbital; l = 0 to (n-1); s=0, p=1, d=2, f=3


What is electronegativity? - ANSWER ✔✔The ability of an atom to

attract electrons in a chemical bond


Which element has the highest electronegativity? - ANSWER

✔✔Fluorine (F)


How does electronegativity trend across a period? - ANSWER

✔✔Increases from left to right


How does electronegativity trend down a group? - ANSWER

✔✔Decreases down a group


What is ionization energy? - ANSWER ✔✔The energy required to

remove an electron from a gaseous atom


How does ionization energy trend across a period? - ANSWER

✔✔Increases from left to right

,How does ionization energy trend down a group? - ANSWER

✔✔Decreases down a group


What is electron affinity? - ANSWER ✔✔The energy change when an

electron is added to a gaseous atom


What is atomic radius? - ANSWER ✔✔The distance from the nucleus

to the outermost electron shell


How does atomic radius trend across a period? - ANSWER

✔✔Decreases from left to right


How does atomic radius trend down a group? - ANSWER

✔✔Increases down a group


What is the formula for molarity (M)? - ANSWER ✔✔M = moles of

solute / liters of solution


What is the formula for molality (m)? - ANSWER ✔✔m = moles of

solute / kilograms of solvent


What is the formula for mole fraction? - ANSWER ✔✔Mole fraction =

moles of component / total moles


What is Avogadro's number? - ANSWER ✔✔6.022 × 10²³ particles

per mole

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, What is the ideal gas law? - ANSWER ✔✔PV = nRT


What is the value of R in the ideal gas law? - ANSWER ✔✔0.0821

L·atm/(mol·K) or 8.314 J/(mol·K)


What is Dalton's law of partial pressures? - ANSWER ✔✔The total

pressure of a gas mixture equals the sum of the partial pressures of

each gas


What is Graham's law of effusion? - ANSWER ✔✔Rate of effusion is

inversely proportional to the square root of molar mass


What is a Lewis acid? - ANSWER ✔✔An electron pair acceptor


What is a Lewis base? - ANSWER ✔✔An electron pair donor


What is a Brønsted-Lowry acid? - ANSWER ✔✔A proton (H⁺) donor


What is a Brønsted-Lowry base? - ANSWER ✔✔A proton (H⁺)

acceptor


What is the pH formula? - ANSWER ✔✔pH = -log[H⁺]


What is the pOH formula? - ANSWER ✔✔pOH = -log[OH⁻]


What is the relationship between pH and pOH? - ANSWER ✔✔pH +

pOH = 14 (at 25°C)

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