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1. Which of the following statements is NOT true: - Correct Answer:
Flumazenil is an antidote to benzodiazepines
Thiamine should be administered to prevent Wernicke syndrome in patients
with suspected alcoholism
Deferoxamine can be used in caffeine and theophylline poisoning.*
Naloxone offsets possible toxic effects of opioid analgesic overdose
2. What is the pharmacokinetic effect of Probencid on the Penicillin drug
class? - Correct Answer: Inhibiting tubular secretion*
3. What is the mechanism of action of the drug tetracycline? - Correct
Answer: Binds to 30S and is bacteriostatic
4. Which of the following principles is important for selecting appropriate
drugs to use in combination chemotherapy? - Correct Answer: Cross-
resistance between drugs should be minimal.
5. Serum creatinine alone is an adequate measure of renal function in the
elderly...T/F? - Correct Answer: False
,6. Obstacles to compliance/adherence in elderly patients include all of the
following except: - Correct Answer: None of the above
7. Ways of improving adherence in pediatric population includes: - Correct
Answer: All of the above
8. Gastric acid secretion is under the control of the following agents EXCEPT: -
Correct Answer: Serotonin
9. The main approach of peptic ulcer treatment is: - Correct Answer: All of
the above
10.Serious side effects of glucocorticoids include the following EXCEPT: -
Correct Answer: acute peptic ulcers
salicylism (vomiting, tinnitus, vertigo)*
11.In humans, the major glucocorticoid is aldosterone and the most
mineralocorticoid is cortisol. T/F? - Correct Answer: False
12.Concerning the release of insulin from beta cells of the pancreas, which of
the following statements is FALSE? - Correct Answer: ATP leads to the
closing of ATP-dependent calcium channels.
13.Which of the following insulins would be most appropriate if you wanted
the most immediate onset of activity? - Correct Answer: Regular insulin
,14.Which drug increases the hepatic metabolism of other drugs? - Correct
Answer: Rifampin
15.Which of the following adverse effects of combined oral contraceptive
therapy does NOT require discontinuation of therapy? - Correct Answer:
breakthrough bleeding
16.Which of the following is NOT a characteristic of myxedema? - Correct
Answer: intolerance to heat
17.A 26 yo woman with leukemia was undergoing chemotherapy with IV
antineoplastic drugs. During treatment, she developed a systematic
infection from an opportunistic pathogen. A white vaginal discharge was
observed from the catheter site. After appropriate specimens were
obtained for culture, empiric antibiotic therapy was started with gentamicin
and nafcillin intravenously. Th patient complained of a sore throat, and
white plaques has appeared in her pharynx. On day 4, the blood and urine
cultures grew Candida albicans.
18.The opportunistic fungal infection in this patient could have been prevented
by administration of ...? - Correct Answer: Fluconazole
19.Most common complication of insulin therapy is: - Correct Answer:
Hypoglycemia
, 20.Tetracycline can treat acne and skin infections. Photosensitivity is a major
complication of its use. Patients should be advised to: - Correct Answer:
avoid direct sunlight
21.All of the following may be used in the treatment of malaria EXCEPT: -
Correct Answer: chloroquine**
atovoquone-proguanil
doxycycline*
Quinine*
22.T4 is four times more potent than T3 - T/F? - Correct Answer: False
23.This medication is used as a monotherapy, is nontoxic, and rapidly
suppresses Hepatitis B Virus. - Correct Answer: Lamivudine
24.An 18-month-old boy presented in a semiconscious state with a blood
pressure of 60/40 and a heart rate of 50 beats per minute after ingesting a
number of his grandmother's metoprolol tablets. In this case, the most
appropriate antidote is - Correct Answer: Glucagon
25.A patient with high fever, chills, and malaise presents with a blood culture
that reveals the presence of gram-negative bacilli. The initial diagnosis is
bacteremia. The records of the patient reveal that she has had a respiratory
distress and rash after oral penicillin G about 5 months ago. The most
appropriate drug regimen for empiric treatment is - Correct Answer:
Aztreonam (Azactam)